Product Name :
β-Actin (4D3) monoclonal antibody Background :
Actin, a ubiquitous eukaryotic protein, is the major component of the cytoskeleton. At least six isoforms are known in mammals. Nonmuscle β- and γ-actin, also known as cytoplasmic actin, are predominantly expressed in nonmuscle cells, controlling cell structure and motility. α-cardiac and α-skeletal actin are expressed in striated cardiac and skeletal muscles, respectively; two smooth muscle actins, α- and γ-actin, are found primarily in vascular smooth muscle and enteric smooth muscle, respectively. These actin isoforms regulate the contractile potential of muscle cells. Product :
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
β-Actin (4D3) detects endogenous levels of β-actin protein. Immunogen :
Recombinant full length Human β-Actin. Conjugate :
Unconjugated Modification :
Unmodified
β-Actin (4D3) monoclonal antibody Background :
Actin, a ubiquitous eukaryotic protein, is the major component of the cytoskeleton. At least six isoforms are known in mammals. Nonmuscle β- and γ-actin, also known as cytoplasmic actin, are predominantly expressed in nonmuscle cells, controlling cell structure and motility. α-cardiac and α-skeletal actin are expressed in striated cardiac and skeletal muscles, respectively; two smooth muscle actins, α- and γ-actin, are found primarily in vascular smooth muscle and enteric smooth muscle, respectively. These actin isoforms regulate the contractile potential of muscle cells. Product :
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
β-Actin (4D3) detects endogenous levels of β-actin protein. Immunogen :
Recombinant full length Human β-Actin. Conjugate :
Unconjugated Modification :
Unmodified
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Western blot (WB) analysis of β-Actin (4D3) mAb at 1:5000-1:20000 dilution Lane1:The Lung tissue lysate of Mouse(20ug) Lane2:The Lung tissue lysate of Rat(20ug) Lane3:H9C2 whole cell lysate(20ug) Lane4:CT26 whole cell lysate(20ug) Lane5:L02 whole cell lysate(20ug) Lane6:HEK293T whole cell lysate(20ug)
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The anti-microbial peptide LL-37/CRAMP levels are associated with acute heart failure and can attenuate cardiac dysfunction in multiple preclinical models of heart failure
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Development of an in vitro cell-sheet cancer model for chemotherapeutic screening
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E3 ligase ZFP91 inhibits Hepatocellular Carcinoma Metabolism Reprogramming by regulating PKM splicing
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Resveratrol improves human umbilical cord-derived mesenchymal stem cells repair for cisplatin-induced acute kidney injury
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Arsenic trioxide ameliorates experimental autoimmune encephalomyelitis in C57BL/6 mice by inducing CD4+ T cell apoptosis
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Exercise downregulates HIPK2 and HIPK2 inhibition protects against myocardial infarction
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A selected small molecule prevents inflammatory osteolysis through restraining osteoclastogenesis by modulating PTEN activity
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Digoxin sensitizes gemcitabine-resistant pancreatic cancer cells to gemcitabine via inhibiting Nrf2 signaling pathway
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Systemic delivery of BACE1 siRNA through neuron-targeted nanocomplexes for treatment of Alzheimer's disease
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The Neuroprotective Effect of Short Chain Fatty Acids Against Sepsis-Associated Encephalopathy in Mice
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Taurine Reprograms Mammary-Gland Metabolism and Alleviates Inflammation Induced by Streptococcus uberis in Mice
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CISD2 inhibition overcomes resistance to sulfasalazine-induced ferroptotic cell death in head and neck cancer
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Arctigenin disrupts NLRP3 inflammasome assembly in colonic macrophages via downregulating fatty acid oxidation to prevent colitis-associated cancer
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Dapagliflozin improves left ventricular remodeling and aorta sympathetic tone in a pig model of heart failure with preserved ejection fraction
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Bone marrow derived mesenchymal stem cells pretreated with erythropoietin accelerate the repair of acute kidney injury
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METTL3/METTL14 transactivation and m6A-dependent TGF-β1 translation in activated Kupffer cells
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Blockade of IDO-Kynurenine-AhR Axis Ameliorated Colitis-Associated Colon Cancer via Inhibiting Immune Tolerance
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Proteasomal cysteine deubiquitinase inhibitor b-AP15 suppresses migration and induces apoptosis in diffuse large B cell lymphoma
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Porcine IGF-1R synonymous mutations in the intracellular domain affect cell proliferation and alter kinase activity
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Porcine IGF1 synonymous mutation alter gene expression and protein binding affinity with IGF1R
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Human Cancer Cells Sense Cytosolic Nucleic Acids Through the RIG-I–MAVS Pathway and cGAS–STING Pathway
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PKCα mediated by the PI3K/Akt-FOXA1 cascade facilitates cypermethrin-induced hyperthyroidism
PMCID: Pubmed No.:33250241
Comparative Transcriptome Analysis Reveals the Protective Mechanism of Glycyrrhinic Acid for Deoxynivalenol-Induced Inflammation and Apoptosis in IPEC-J2 Cells
PMCID: Pubmed No.:33163144
Theaflavin 3, 3-Digallate Delays Ovarian Aging by Improving Oocyte Quality and Regulating Granulosa Cell Function
PMCID: Pubmed No.:34925699
Impaired Autophagy Induced by oxLDL/β2GPI/anti-β2GPI Complex through PI3K/AKT/mTOR and eNOS Signaling Pathways Contributes to Endothelial Cell Dysfunction
PMCID: Pubmed No.:34221236
Human urinary kininogenase reduces the endothelial injury by inhibiting Pyk2/MCU pathway
PMCID: Pubmed No.:34543986
Discovery of novel 3-hydroxyandrosta-5,7-Diene-17-Carboxylic acid derivatives as anti-inflammatory bowel diseases (IBD) agents
PMCID: Pubmed No.:33933753
PIM1 kinase promotes cell proliferation, metastasis and tumor growth of lung adenocarcinoma by potentiating the c-MET signaling pathway
PMCID: Pubmed No.:30583073
Association between ARID2 and RAS-MAPK pathway in intellectual disability and short stature
PMCID: Pubmed No.:33051312
Dendritic cells-derived interferon-λ1 ameliorated inflammatory bone destruction through inhibiting osteoclastogenesis
PMCID: Pubmed No.:32488049
Recombinant milk fat globule-EGF factor-8 reduces apoptosis via integrin β3/FAK/PI3K/AKT signaling pathway in rats after traumatic brain injury
PMCID: Pubmed No.:30154436
Isoform specific FBXW7 mediates NOTCH1 Abruptex mutation C1133Y deregulation in oral squamous cell carcinoma
PMCID: Pubmed No.:32792479
Heat stress affects fetal brain and intestinal function associated with the alterations of placental barrier in late pregnant mouse
PMCID: Pubmed No.:34695613
Effect of chlorogenic acid on alleviating inflammation and apoptosis of IPEC-J2 cells induced by deoxyniyalenol
PMCID: Pubmed No.:32961488
Nrf2 Down-Regulation by Camptothecin Favors Inhibiting Invasion, Metastasis and Angiogenesis in Hepatocellular Carcinoma
PMCID: Pubmed No.:34178646
Neuroprotective effects of INT-777 against Aβ1–42-induced cognitive impairment, neuroinflammation, apoptosis, and synaptic dysfunction in mice
PMCID: Pubmed No.:29935310
Sirtuin 1 alleviates diabetic neuropathic pain by regulating synaptic plasticity of spinal dorsal horn neurons
PMCID: Pubmed No.:30649099
Bmi1 Overexpression in Mesenchymal Stem Cells Exerts Antiaging and Antiosteoporosis Effects by Inactivating p16/p19 Signaling and Inhibiting Oxidative Stress
PMCID: Pubmed No.:30895687
Upregulated osterix promotes invasion and bone metastasis and predicts for a poor prognosis in breast cancer
PMCID: Pubmed No.:30631043
Suppressing the Na + /H + exchanger 1: a new sight to treat depression
PMCID: Pubmed No.:31068571
Alpinetin exerts anti-colitis efficacy by activating AhR, regulating miR-302/DNMT-1/CREB signals, and therefore promoting Treg differentiation
PMCID: Pubmed No.:30166541
LYW-6, a novel cryptotanshinone derived STAT3 targeting inhibitor, suppresses colorectal cancer growth and metastasis
PMCID: Pubmed No.:31982491
Sinusoidal Electromagnetic Fields Increase Peak Bone Mass in Rats by Activating Wnt10b/β‐Catenin in Primary Cilia of Osteoblasts
PMCID: Pubmed No.:30779853
Effects of Molecular Hydrogen on Methamphetamine-Induced Neurotoxicity and Spatial Memory Impairment
PMCID: Pubmed No.:31396089
Timosaponin AIII Induces G2/M Arrest and Apoptosis in Breast Cancer by Activating the ATM/Chk2 and p38 MAPK Signaling Pathways
PMCID: Pubmed No.:33628174
Empagliflozin Alleviates Hepatic Steatosis by Activating the AMPK-TET2-Autophagy Pathway in vivo and in vitro
PMCID: Pubmed No.:33551821
Piperazine-Derived α1D/1A Antagonist 1- Benzyl-N- (3-(4- (2-Methoxyphenyl) Piperazine-1-yl) Propyl) -1H- Indole-2- Carboxamide Induces Apoptosis in Benign Prostatic Hyperplasia Independently of α1-Adrenoceptor Blocking
PMCID: Pubmed No.:33584271
Puerarin Prevents Acute Liver Injury via Inhibiting Inflammatory Responses and ZEB2 Expression
PMCID: Pubmed No.:34421621
Neuroprotective Effects of Shenqi Fuzheng Injection in a Transgenic SOD1-G93A Mouse Model of Amyotrophic Lateral Sclerosis
PMCID: Pubmed No.:34737697
Angelicin Alleviates Post-Trauma Osteoarthritis Progression by Regulating Macrophage Polarization via STAT3 Signaling Pathway
PMCID: Pubmed No.:34177582
PTEN Methylation Promotes Inflammation and Activation of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis
PMCID: Pubmed No.:34305608
Functions of resolvin D1-ALX/FPR2 receptor interaction in the hemoglobin-induced microglial inflammatory response and neuronal injury
PMCID: Pubmed No.:32795323
Actin polymerization state regulates osteogenic differentiation in human adipose-derived stem cells
PMCID: Pubmed No.:33858321
FasL-PDPK1 Pathway Promotes the Cytotoxicity of CD8 + T Cells During Ischemic Stroke
PMCID: Pubmed No.:32036560
Ambient PM2.5 caused cardiac dysfunction through FoxO1-targeted cardiac hypertrophy and macrophage-activated fibrosis in mice
PMCID: Pubmed No.:31978653
Electroacupuncture Pretreatment Prevents Cognitive Impairment Induced by Cerebral Ischemia–Reperfusion via Adenosine A1 Receptors in Rats
PMCID: Pubmed No.:34413765
TBX15/miR-152/KIF2C pathway regulates breast cancer doxorubicin resistance via promoting PKM2 ubiquitination
PMCID: Pubmed No.:34663310
Novel Regulatory Roles of Wnt1 in Infection-Associated Colorectal Cancer
PMCID: Pubmed No.:29626750
Cytoplasmic eIF6 promotes OSCC malignant behavior through AKT pathway
PMCID: Pubmed No.:34922580
linc00968 inhibits the tumorigenesis and metastasis of lung adenocarcinoma via serving as a ceRNA against miR-9-5p and increasing CPEB3
PMCID: Pubmed No.:33159015
linc00968 inhibits the tumorigenesis and metastasis of lung adenocarcinoma via serving as a ceRNA against miR-9-5p and increasing CPEB3
PMCID: Pubmed No.:33159015
Long-term every-other-day administration of DMAMCL has little effect on aging and age-associated physiological decline in mice
PMCID: Pubmed No.:31048563
Improving radio-chemotherapy efficacy of prostate cancer by co-deliverying docetaxel and dbait with biodegradable nanoparticles
PMCID: Pubmed No.:31858836
SIRT1 Decreases Emotional Pain Vulnerability with Associated CaMKIIα Deacetylation in Central Amygdala
PMCID: Pubmed No.:32005763
Nrf2 inhibition reverses resistance to GPX4 inhibitor-induced ferroptosis in head and neck cancer
PMCID: Pubmed No.:30339884
Dual Mechanisms of Novel CD73-Targeted Antibody and Antibody–Drug Conjugate in Inhibiting Lung Tumor Growth and Promoting Antitumor Immune-Effector Function
PMCID: Pubmed No.:32943546
Curcumin Sensitizes Prolactinoma Cells to Bromocriptine by Activating the ERK/EGR1 and Inhibiting the AKT/GSK-3β Signaling Pathway In Vitro and In Vivo
PMCID: Pubmed No.:34463926
Expression of a short antibody heavy chain peptide effectively antagonizes adenosine 2A receptor in vitro and in vivo
PMCID: Pubmed No.:32308059
Corydalis saxicola Bunting total alkaloids attenuate paclitaxel-induced peripheral neuropathy through PKCε/p38 MAPK/TRPV1 signaling pathway
PMCID: Pubmed No.:34281577
TGF-β1/IL-11/MEK/ERK signaling mediates senescence-associated pulmonary fibrosis in a stress-induced premature senescence model of Bmi-1 deficiency
PMCID: Pubmed No.:31959867
Alhagi honey polysaccharides attenuate intestinal injury and immune suppression in cyclophosphamide-induced mice
PMCID: Pubmed No.:34128029
JNK1 regulates RANKL-induced osteoclastogenesis via activation of a novel Bcl-2-Beclin1-autophagy pathway
PMCID: Pubmed No.:31295022
Diallyl disulfide alleviates inflammatory osteolysis by suppressing osteoclastogenesis via NF-κB–NFATc1 signal pathway
PMCID: Pubmed No.:30857415
Mogrol, an aglycone of mogrosides, attenuates ulcerative colitis by promoting AMPK activation
PMCID: Pubmed No.:33296813
Bryodulcosigenin a natural cucurbitane-type triterpenoid attenuates dextran sulfate sodium (DSS)-induced colitis in mice
PMCID: Pubmed No.:34798522
The protective effect of WKYMVm peptide on inflammatory osteolysis through regulating NF-κB and CD9/gp130/STAT3 signalling pathway
PMCID: Pubmed No.:31837208
Curcumin improves memory deficits by inhibiting HMGB1-RAGE/TLR4-NF-κB signalling pathway in APPswe/PS1dE9 transgenic mice hippocampus
PMCID: Pubmed No.:34405526
Dihydromyricetin resists inflammation-induced muscle atrophy via ryanodine receptor-CaMKK-AMPK signal pathway
PMCID: Pubmed No.:34676967
Novel Sesquiterpene Glycoside from Loquat Leaf Alleviates Type 2 Diabetes Mellitus Combined with Nonalcoholic Fatty Liver Disease by Improving Insulin Resistance, Oxidative Stress, Inflammation, and Gut Microbiota Composition
PMCID: Pubmed No.:34783554
trans 10, cis 12, but Not cis 9, trans 11 Conjugated Linoleic Acid Isomer Enhances Exercise Endurance by Increasing Oxidative Skeletal Muscle Fiber Type via Toll-like Receptor 4 Signaling in Mice
PMCID: Pubmed No.:34928153
trans 10, cis 12, but Not cis 9, trans 11 Conjugated Linoleic Acid Isomer Enhances Exercise Endurance by Increasing Oxidative Skeletal Muscle Fiber Type via Toll-like Receptor 4 Signaling in Mice
PMCID: Pubmed No.:34928153
Pulsed Electromagnetic Fields Ameliorate Skeletal Deterioration in Bone Mass, Microarchitecture, and Strength by Enhancing Canonical Wnt Signaling-Mediated Bone Formation in Rats with Spinal Cord Injury
PMCID: Pubmed No.:33108939
Butyrate Suppresses Glucose Metabolism of Colorectal Cancer Cells via GPR109a-AKT Signaling Pathway and Enhances Chemotherapy
PMCID: Pubmed No.:33855046
Resveratrol Improves Mitochondrial Biogenesis Function and Activates PGC-1α Pathway in a Preclinical Model of Early Brain Injury Following Subarachnoid Hemorrhage
PMCID: Pubmed No.:33968980
Imperatorin inhibits mitogen-activated protein kinase and nuclear factor kappa-B signaling pathways and alleviates neuroinflammation in ischemic stroke
PMCID: Pubmed No.:34674376
NR4A1 enhances MKP7 expression to diminish JNK activation induced by ROS or ER-stress in pancreatic β cells for surviving
PMCID: Pubmed No.:34088892
Effects of ALA-PDT on the Healing of Mouse Skin Wounds Infected With Pseudomonas aeruginosa and Its Related Mechanisms.
PMCID: Pubmed No.:33344449
Pyk2/MCU Pathway as a New Target for Reversing Atherosclerosis
PMCID: Pubmed No.:34026753
Selenium nanoparticles fabricated in laminarin polysaccharides solutions exert their cytotoxicities in HepG2 cells by inhibiting autophagy and promoting apoptosis
PMCID: Pubmed No.:31284007
N16 suppresses RANKL-mediated osteoclatogenesis by down-regulating RANK expression
PMCID: Pubmed No.:31751723
QKI, a miR‐200 target gene, suppresses epithelial‐to‐mesenchymal transition and tumor growth
PMCID: Pubmed No.:31026342
Paired associative stimulation improves synaptic plasticity and functional outcomes after cerebral ischemia
PMCID: Pubmed No.:31290455
Inhibition of Uncoupling Protein 2 Enhances the Radiosensitivity of Cervical Cancer Cells by Promoting the Production of Reactive Oxygen Species
PMCID: Pubmed No.:32190174
Activation of GPR55 attenuates cognitive impairment and neurotoxicity in a mouse model of Alzheimer's disease induced by Aβ1–42 through inhibiting RhoA/ROCK2 pathway
PMCID: Pubmed No.:34363866
A novel compound AB38b attenuates oxidative stress and ECM protein accumulation in kidneys of diabetic mice through modulation of Keap1/Nrf2 signaling
PMCID: Pubmed No.:31645661
Exploring the protective effects of schizandrol A in acute myocardial ischemia mice by comprehensive metabolomics profiling integrated with molecular mechanism studies
PMCID: Pubmed No.:32123298
Diabetes downregulates peptide transporter 1 in the rat jejunum: possible involvement of cholate-induced FXR activation
PMCID: Pubmed No.:32341465
Sirt1 inhibits renal tubular cell epithelial–mesenchymal transition through YY1 deacetylation in diabetic nephropathy
PMCID: Pubmed No.:32555442
Short-chain fatty acids exert opposite effects on the expression and function of p-glycoprotein and breast cancer resistance protein in rat intestine
PMCID: Pubmed No.:32555444
Fluoxetine induces lipid metabolism abnormalities by acting on the liver in patients and mice with depression
PMCID: Pubmed No.:30150788
Suppression of MIF-induced neuronal apoptosis may underlie the therapeutic effects of effective components of Fufang Danshen in the treatment of Alzheimer's disease
PMCID: Pubmed No.:29770796
Neotuberostemonine inhibits the differentiation of lung fibroblasts into myofibroblasts in mice by regulating HIF-1α signaling
PMCID: Pubmed No.:29645000
Effect of hyperglycemia on microglial polarization after cerebral ischemia-reperfusion injury in rats
PMCID: Pubmed No.:34052292
Oxymatrine alleviated hepatic lipid metabolism via regulating miR-182 in non-alcoholic fatty liver disease
PMCID: Pubmed No.:32679144
1‐L‐MT, an IDO inhibitor, prevented colitis‐associated cancer by inducing CDC20 inhibition‐mediated mitotic death of colon cancer cells
PMCID: Pubmed No.:29607498
mTORC1 promotes mineralization via p53 pathway
PMCID: Pubmed No.:33508145
Differential skeletal response in adult and aged rats to independent and combinatorial stimulation with pulsed electromagnetic fields and mechanical vibration
PMCID: Pubmed No.:31908035
Thrombin/PAR-1 activation induces endothelial damages via NLRP1 inflammasome in gestational diabetes
PMCID: Pubmed No.:32059841
Necroptosis mediated by impaired autophagy flux contributes to adverse ventricular remodeling after myocardial infarction
PMCID: Pubmed No.:32179044
Ferulic acid attenuates oxidative DNA damage and inflammatory responses in microglia induced by benzo(a)pyrene
PMCID: Pubmed No.:31699670
Inhibition of GPR17 with cangrelor improves cognitive impairment and synaptic deficits induced by Aβ1–42 through Nrf2/HO-1 and NF-κB signaling pathway in mice
PMCID: Pubmed No.:34781121
JLX001 ameliorates cerebral ischemia injury by modulating microglial polarization and compromising NLRP3 inflammasome activation via the NF-κB signaling pathway
PMCID: Pubmed No.:34740080
A novel chrysin thiazole derivative polarizes macrophages to an M1 phenotype via targeting TLR4
PMCID: Pubmed No.:33182070
5-HT2A Receptor and 5-HT Degradation Play a Crucial Role in Atherosclerosis by Modulating Macrophage Foam Cell Formation, Vascular Endothelial Cell Inflammation, and Hepatic Steatosis
PMCID: Pubmed No.:33536397
The RhoA/ROCK pathway mediates high glucose-induced cardiomyocyte apoptosis via oxidative stress, JNK, and p38MAPK pathways
PMCID: Pubmed No.:29745021
Serum- and glucocorticoid-inducible kinase 1 promotes insulin resistance in adipocytes via degradation of insulin receptor substrate 1
PMCID: Pubmed No.:33724645
DNA damage checkpoint pathway modulates the regulation of skeletal growth and osteoblastic bone formation by parathyroid hormone-related peptide
PMCID: Pubmed No.:29805302
The loss of dopaminergic neurons in DEC1 deficient mice potentially involves the decrease of PI3K/Akt/GSK3β signaling
PMCID: Pubmed No.:31884423
Epothilone B prevents lipopolysaccharide-induced inflammatory osteolysis through suppressing osteoclastogenesis via STAT3 signaling pathway
PMCID: Pubmed No.:32527985
Neuromedin B modulates phosphate-induced vascular calcification
PMCID: Pubmed No.:34674793
Hsa-let-7c controls the committed differentiation of IGF-1-treated mesenchymal stem cells derived from dental pulps by targeting IGF-1R via the MAPK pathways
PMCID: Pubmed No.:29650947
A Novel Phytochemical, DIM, Inhibits Proliferation, Migration, Invasion and TNF-α Induced Inflammatory Cytokine Production of Synovial Fibroblasts From Rheumatoid Arthritis Patients by Targeting MAPK and AKT/mTOR Signal Pathway
PMCID: Pubmed No.:31396207
MFG-E8 attenuates inflammation in subarachnoid hemorrhage by driving microglial M2 polarization
PMCID: Pubmed No.:33245889
Jmjd3 is involved in the susceptibility to depression induced by maternal separation via enhancing the neuroinflammation in the prefrontal cortex and hippocampus of male rats
PMCID: Pubmed No.:32084453
Protective effects of FGF10 on neurovascular unit in a rat model of neonatal hypoxic-ischemic brain injury
PMCID: Pubmed No.:32610105
Role of TREM-1 in the development of early brain injury after subarachnoid hemorrhage
PMCID: Pubmed No.:33727099
Decursinol angelate ameliorates 12-O-tetradecanoyl phorbol-13-acetate (TPA) -induced NF-κB activation on mice ears by inhibiting exaggerated inflammatory cell infiltration, oxidative stress and pro-inflammatory cytokine production
PMCID: Pubmed No.:31351099
Anthraquinone-type inhibitor of α-glucosidase enhances glucose uptake by activating an insulin-like signaling pathway in C2C12 myotubes
PMCID: Pubmed No.:31071387
Toosendanin Shows Potent Efficacy Against Human Ovarian Cancer through Caspase-Dependent Mitochondrial Apoptotic Pathway
PMCID: Pubmed No.:34521317
Schisandrin B Attenuates Colitis-Associated Colorectal Cancer through SIRT1 Linked SMURF2 Signaling
PMCID: Pubmed No.:34632965
Chicoric Acid Improves Heart and Blood Responses to Hypobaric Hypoxia in Tibetan Yaks
PMCID: Pubmed No.:29433395
Protective effects of melatonin on sepsis-induced liver injury and dysregulation of gluconeogenesis in rats through activating SIRT1/STAT3 pathway
PMCID: Pubmed No.:31234024
Metabolomic profiling of metoprolol-induced cardioprotection in a murine model of acute myocardial ischemia
PMCID: Pubmed No.:31972362
Curcumin regulates endogenous and exogenous metabolism via Nrf2-FXR-LXR pathway in NAFLD mice
PMCID: Pubmed No.:29860219
MyoD1 suppresses cell migration and invasion by inhibiting FUT4 transcription in human gastric cancer cells
PMCID: Pubmed No.:31831855
LncRNA AK077216 promotes RANKL‐induced osteoclastogenesis and bone resorption via NFATc1 by inhibition of NIP45
PMCID: Pubmed No.:30132869
Long Noncoding RNA ANRIL Supports Proliferation of Adult T-Cell Leukemia Cells through Cooperation with EZH2
PMCID: Pubmed No.:30258009
Resolvin D1 Attenuates Innate Immune Reactions in Experimental Subarachnoid Hemorrhage Rat Model
PMCID: Pubmed No.:33411245
NR4A1 counteracts JNK activation incurred by ER stress or ROS in pancreatic β‐cells for protection
PMCID: Pubmed No.:33124187
Alpha lipoic acid inhibits oxidative stress‐induced apoptosis by modulating of Nrf2 signalling pathway after traumatic brain injury
PMCID: Pubmed No.:30989783
PTEN negatively regulates the expression of pro-inflammatory cytokines and chemokines of fibroblast-like synoviocytes in adjuvant-induced arthritis
PMCID: Pubmed No.:31842626
Emodin prevents renal ischemia-reperfusion injury via suppression of CAMKII/DRP1-mediated mitochondrial fission
PMCID: Pubmed No.:34793771
Hippocampal SIRT1 improves cognitive impairment by deacetylating tau protein in diabetic models
PMCID: Pubmed No.:34861210
A pentacyclic triterpene derivative possessing polyhydroxyl ring A suppresses growth of HeLa cells by reactive oxygen species-dependent NF-κB pathway
PMCID: Pubmed No.:30153443
Iso-suillin-induced DNA damage leading to cell cycle arrest and apoptosis arised from p53 phosphorylation in A549 cells
PMCID: Pubmed No.:34217708
Ovine viperin inhibits bluetongue virus replication
PMCID: Pubmed No.:32784101
Integrating bioinformatics with pharmacological evaluation for illustrating the action mechanism of herbal formula Jiao'e mixture in suppressing lung carcinoma
PMCID: Pubmed No.:34400263
Inhibitory effect of INT-777 on lipopolysaccharide-induced cognitive impairment, neuroinflammation, apoptosis, and synaptic dysfunction in mice
PMCID: Pubmed No.:30144494
Silymarin ameliorates the disordered glucose metabolism of mice with diet-induced obesity by activating the hepatic SIRT1 pathway
PMCID: Pubmed No.:33901577
Melatonin ameliorates excessive PINK1/Parkin-mediated mitophagy by enhancing SIRT1 expression in granulosa cells of PCOS
PMCID: Pubmed No.:32343612
Atractylenolide III ameliorates cerebral ischemic injury and neuroinflammation associated with inhibiting JAK2/STAT3/Drp1-dependent mitochondrial fission in microglia
PMCID: Pubmed No.:30981186
Eupatilin ameliorates dextran sulphate sodium-induced colitis in mice partly through promoting AMPK activation
PMCID: Pubmed No.:30097122
Decreased immunoglobulin G in brain regions of elder female APOE4-TR mice accompany with Aβ accumulation
PMCID: Pubmed No.:30700991
Radiosensitizing effect of gold nanoparticle loaded with small interfering RNA-SP1 on lung cancer: AuNPs-si-SP1 regulates GZMB for radiosensitivity
PMCID: Pubmed No.:34517158
Resveratrol chemosensitizes adriamycin‐resistant breast cancer cells by modulating miR‐122‐5p
PMCID: Pubmed No.:31155753
The influence of the Chuyou Yuyang granule on the Toll‐like receptor/nuclear factor‐κB signal pathway in Helicobacter pylori‐positive peptic ulcer patients
PMCID: Pubmed No.:31034651
Simultaneous interference of SP1 and HIF1α retarding the proliferation, migration, and invasion of human microvascular endothelial cells (HMEC‐1) under hypoxia
PMCID: Pubmed No.:31135072
Alpha-Mangostin Ameliorates Bleomycin-Induced Pulmonary Fibrosis in Mice Partly Through Activating Adenosine 5′-Monophosphate-Activated Protein Kinase
PMCID: Pubmed No.:31798444
MicroRNA-141-5p Acts as a Tumor Suppressor via Targeting RAB32 in Chronic Myeloid Leukemia
PMCID: Pubmed No.:32038235
Sodium Houttuyfonate Alleviates Post-infarct Remodeling in Rats via AMP-Activated Protein Kinase Pathway
PMCID: Pubmed No.:30319423
Hederagenin Attenuates Cerebral Ischaemia/Reperfusion Injury by Regulating MLK3 Signalling
PMCID: Pubmed No.:32848779
Indoprofen exerts a potent therapeutic effect against sepsis by alleviating high mobility group box 1-mediated inflammatory responses
PMCID: Pubmed No.:34755645
Albumin fusion improves the pharmacokinetics and in vivo antitumor efficacy of canine interferon gamma
PMCID: Pubmed No.:30639219
Artemisinin Derivatives Inhibit Non-small Cell Lung Cancer Cells Through Induction of ROS-dependent Apoptosis/Ferroptosis
PMCID: Pubmed No.:34093811
Probiotics Exert Protective Effect against Sepsis-Induced Cognitive Impairment by Reversing Gut Microbiota Abnormalities
PMCID: Pubmed No.:33284020
Clostridium butyricum Attenuates Chronic Unpredictable Mild Stress-Induced Depressive-Like Behavior in Mice via the Gut-Brain Axis
PMCID: Pubmed No.:30040410
The Neuropeptide Spexin Promotes the Osteoblast Differentiation of MC3T3-E1 Cells via the MEK/ERK Pathway and Bone Regeneration in a Mouse Calvarial Defect Model
PMCID: Pubmed No.:34951679
Protection of the enhanced Nrf2 deacetylation and its downstream transcriptional activity by SIRT1 in myocardial ischemia/reperfusion injury
PMCID: Pubmed No.:34403762
Caveolin-1 knockout mice have altered serum N-glycan profile and sialyltransferase tissue expression
PMCID: Pubmed No.:34462883
Factor Xa inhibitor rivaroxaban suppresses experimental abdominal aortic aneurysm progression via attenuating aortic inflammation
PMCID: Pubmed No.:33227452
NEDD4 Negatively Regulates GITR via Ubiquitination in Immune Microenvironment of Melanoma
PMCID: Pubmed No.:31824170
Lanosterol modulates proteostasis via dissolving cytosolic sequestosomes/aggresome-like induced structures
PMCID: Pubmed No.:31785334
The positive role of vitronectin in radiation induced lung toxicity: the in vitro and in vivo mechanism study
PMCID: Pubmed No.:29661186
Hepatoprotective Effect of Apigenin Against Liver Injury via the Non-canonical NF-κB Pathway In Vivo and In Vitro
PMCID: Pubmed No.:32458347
Protective effects of Genistein on the cognitive deficits induced by chronic sleep deprivation
PMCID: Pubmed No.:32115816
Sarsasapogenin ameliorates diabetes‐associated memory impairment and neuroinflammation through down‐regulation of PAR‐1 receptor
PMCID: Pubmed No.:33885189
Protective effects of sarsasapogenin against early stage of diabetic nephropathy in rats
PMCID: Pubmed No.:29682805
A novel compound AB-38b improves diabetes-associated cognitive decline in mice via activation of Nrf2/ARE pathway
PMCID: Pubmed No.:31132419
Inhibition of Autophagy with Chloroquine Enhanced Sinoporphyrin Sodium Mediated Photodynamic Therapy-induced Apoptosis in Human Colorectal Cancer Cells
PMCID: Pubmed No.:30662343
Interleukin-27 prevents LPS-induced inflammatory osteolysis by inhibiting osteoclast formation and function
PMCID: Pubmed No.:30972153
P27 deletion enhances hematopoiesis by paracrine action of IL22 secreted from bone marrow mesenchymal stem cells
PMCID: Pubmed No.:32269712
Inactivation of TSC1 promotes epithelial-mesenchymal transition of renal tubular epithelial cells in mouse diabetic nephropathy
PMCID: Pubmed No.:31235817
Astragaloside IV ameliorates neuroinflammation-induced depressive-like behaviors in mice via the PPARγ/NF-κB/NLRP3 inflammasome axis
PMCID: Pubmed No.:29795356
Inhibitory effects of isocryptotanshinone on gastric cancer
PMCID: Pubmed No.:29915371
Attenuation of melanogenesis by Nymphaea nouchali (Burm. f) flower extract through the regulation of cAMP/CREB/MAPKs/MITF and proteasomal degradation of tyrosinase
PMCID: Pubmed No.:30224716
Neuroprotective Effects of Rhynchophylline Against Aβ1–42-Induced Oxidative Stress, Neurodegeneration, and Memory Impairment Via Nrf2–ARE Activation
PMCID: Pubmed No.:34170454
DR7 encoded by human herpesvirus 6 promotes glioma development and progression
PMCID: Pubmed No.:30881135
The biphasic effects of the oxLDL/β2GPI/anti-β2GPI complex on VSMC proliferation and apoptosis
PMCID: Pubmed No.:30738928
BMP9 inhibits the proliferation and migration of fibroblast-like synoviocytes in rheumatoid arthritis via the PI3K/AKT signaling pathway
PMCID: Pubmed No.:31203157
MCTR3 reduces LPS-induced acute lung injury in mice via the ALX/PINK1 signaling pathway
PMCID: Pubmed No.:33268042
Saikosaponin-d attenuated lipopolysaccharide-induced depressive-like behaviors via inhibiting microglia activation and neuroinflammation
PMCID: Pubmed No.:31926446
Inhibiting NLRP3 inflammasome with MCC950 ameliorates perioperative neurocognitive disorders, suppressing neuroinflammation in the hippocampus in aged mice
PMCID: Pubmed No.:32087497
Effects of interleukin-6 and IL-6/AMPK signaling pathway on mitochondrial biogenesis and astrocytes viability under experimental septic condition
PMCID: Pubmed No.:29674256
Hyperoside suppresses BMP-7-dependent PI3K/AKT pathway in human hepatocellular carcinoma cells
PMCID: Pubmed No.:34532370
Syngeneic bone marrow transplantation in combination with PI3K inhibitor reversed hyperglycemia in later-stage streptozotocin-induced diabetes
PMCID: Pubmed No.:34988151
Impairment of Intestinal Monocarboxylate Transporter 6 Function and Expression in Diabetic Rats Induced by Combination of High-Fat Diet and Low Dose of Streptozocin: Involvement of Butyrate–Peroxisome Proliferator-Activated Receptor-γ Activation
PMCID: Pubmed No.:30923035
Prediction of Atorvastatin Pharmacokinetics in High-Fat Diet and Low-Dose Streptozotocin-Induced Diabetic Rats Using a Semiphysiologically Based Pharmacokinetic Model Involving Both Enzymes and Transporters
PMCID: Pubmed No.:31399507
The Role of CDR1as in Proliferation and Differentiation of Human Umbilical Cord-Derived Mesenchymal Stem Cells
PMCID: Pubmed No.:31281369
Polydatin protects SH-SY5Y in models of Parkinson's disease by promoting Atg5-mediated but parkin-independent autophagy
PMCID: Pubmed No.:31926197
Curcumin-activated autophagy plays a negative role in its anti-osteoclastogenic effect
PMCID: Pubmed No.:31678610
Protective Effects of 1-Methylnicotinamide on Aβ1–42-Induced Cognitive Deficits, Neuroinflammation and Apoptosis in Mice
PMCID: Pubmed No.:30635816
Paeonol Inhibits Oxidized Low-Density Lipoprotein-Induced Vascular Endothelial Cells Autophagy by Upregulating the Expression of miRNA-30a
PMCID: Pubmed No.:29472864
UPLC/Q-TOFMS-Based Metabolomics Approach to Reveal the Protective Role of Other Herbs in An-Gong-Niu-Huang Wan Against the Hepatorenal Toxicity of Cinnabar and Realgar
PMCID: Pubmed No.:29950994
Novobiocin, a Newly Found TRPV1 Inhibitor, Attenuates the Expression of TRPV1 in Rat Intestine and Intestinal Epithelial Cell Line IEC-6
PMCID: Pubmed No.:30374305
Identification of extracellular vesicles-transported miRNAs in Erlotinib-resistant head and neck squamous cell carcinoma
PMCID: Pubmed No.:32157550
hucMSCs Attenuate IBD through Releasing miR148b-5p to Inhibit the Expression of 15-lox-1 in Macrophages
PMCID: Pubmed No.:31275059
Both LmCYP4G genes function in decreasing cuticular penetration of insecticides in Locusta migratoria
PMCID: Pubmed No.:32419293
Effect of simvastatin and microRNA-21 inhibitor on metastasis and progression of human salivary adenoid cystic carcinoma
PMCID: Pubmed No.:30021341
CXCR1/CXCR2 antagonist G31P inhibits nephritis in a mouse model of uric acid nephropathy
PMCID: Pubmed No.:30257327
Norfloxacin suppresses Leptospira-induced inflammation through inhibiting p65 and ERK phosphorylation and NLRP3 inflammasome activation
PMCID: Pubmed No.:34826552
Activation of the G Protein-Coupled Estrogen Receptor Elicits Store Calcium Release and Phosphorylation of the Mu-Opioid Receptors in the Human Neuroblastoma SH-SY5Y Cells
PMCID: Pubmed No.:31920512
MiR-146a Ameliorates Hemoglobin-Induced Microglial Inflammatory Response via TLR4/IRAK1/TRAF6 Associated Pathways
PMCID: Pubmed No.:32317924
The novel GLP-1/GIP dual agonist DA3-CH is more effective than liraglutide in reducing endoplasmic reticulum stress in diabetic rats with cerebral ischemia-reperfusion injury
PMCID: Pubmed No.:33500109
Essential oil from Fructus Alpinia zerumbet (fruit of Alpinia zerumbet (Pers.) Burtt.et Smith) protected against aortic endothelial cell injury and inflammation in vitro and in vivo
PMCID: Pubmed No.:30880260
Mechanisms dissection of the combination GRS derived from ShengMai preparations for the treatment of myocardial ischemia/reperfusion injury
PMCID: Pubmed No.:32946961
A balanced game: chicken macrophage response to ALV-J infection
PMCID: Pubmed No.:30841905
Dexmedetomidine Attenuates Neuroinflammatory–Induced Apoptosis after Traumatic Brain Injury via Nrf2 signaling pathway
PMCID: Pubmed No.:31478596
Baicalin Protects Mice Brain From Apoptosis in Traumatic Brain Injury Model Through Activation of Autophagy
PMCID: Pubmed No.:30686973
Carbon ion combined with tigecycline inhibits lung cancer cell proliferation by inducing mitochondrial dysfunction
PMCID: Pubmed No.:33065148
PGRN−/− TAMs-derived exosomes inhibit breast cancer cell invasion and migration and its mechanism exploration
PMCID: Pubmed No.:33181174
Perilla aldehyde attenuates CUMS-induced depressive-like behaviors via regulating TXNIP/TRX/NLRP3 pathway in rats
PMCID: Pubmed No.:29800538
Overexpression of miR-146a Might Regulate Polarization Transitions of BV-2 Cells Induced by High Glucose and Glucose Fluctuations
PMCID: Pubmed No.:31695681
Antitumor activity of Koningic acid in thyroid cancer by inhibiting cellular glycolysis
PMCID: Pubmed No.:34264510
Effects of low-dose ALA-PDT on fibroblast photoaging induced by UVA irradiation and the underlying mechanisms
PMCID: Pubmed No.:31075320
HHQ-4, a quinoline derivate, preferentially inhibits proliferation of glucose-deprived breast cancer cells as a GRP78 down-regulator
PMCID: Pubmed No.:31022492
Fluoride induces apoptosis via inhibiting SIRT1 activity to activate mitochondrial p53 pathway in human neuroblastoma SH-SY5Y cells
PMCID: Pubmed No.:29609003
CTRP9 induces iNOS expression through JAK2/STAT3 pathway in Raw 264.7 and peritoneal macrophages
PMCID: Pubmed No.:31837806
Bmi-1 determines the stemness of renal stem or progenitor cells
PMCID: Pubmed No.:32819581
Shp2 regulates PM2.5-induced airway epithelial barrier dysfunction by modulating ERK1/2 signaling pathway
PMCID: Pubmed No.:34252507
Tert-butylhydroquinone enhanced angiogenesis and astrocyte activation by activating nuclear factor-E2-related factor 2/heme oxygenase-1 after focal cerebral ischemia in mice
PMCID: Pubmed No.:31283926
PID1 in adipocytes modulates whole-body glucose homeostasis
PMCID: Pubmed No.:29391195
Liver proteomics analysis reveals abnormal metabolism of bile acid and arachidonic acid in Chinese hamsters with type 2 diabetes mellitus
PMCID: Pubmed No.:33722748
Involvement of NLRP3 inflammasome in methamphetamine-induced microglial activation through miR-143/PUMA axis
PMCID: Pubmed No.:30394308
Absent in melanoma 2 suppresses epithelial‐mesenchymal transition via Akt and inflammasome pathways in human colorectal cancer cells
PMCID: Pubmed No.:31210372
miR‐125a‐3p suppresses the growth and progression of papillary thyroid carcinoma cell by targeting MMP11
PMCID: Pubmed No.:31489990
Luteolin attenuates high glucose-induced podocyte injury via suppressing NLRP3 inflammasome pathway
PMCID: Pubmed No.:30935950
Breviscapine provides a neuroprotective effect after traumatic brain injury by modulating the Nrf2 signaling pathway
PMCID: Pubmed No.:31042302
Taurine-Mediated IDOL Contributes to Resolution of Streptococcus uberis Infection | Infection and Immunity
PMCID: Pubmed No.:33593888
Tprn is essential for the integrity of stereociliary rootlet in cochlear hair cells in mice
PMCID: Pubmed No.:30159668
YAP mediates the interaction between the Hippo and PI3K/Akt pathways in mesangial cell proliferation in diabetic nephropathy
PMCID: Pubmed No.:32816106
Adipocytes induce the resistance of ovarian cancer to carboplatin through ANGPTL4
PMCID: Pubmed No.:32705217
Flavonoids extracted from mulberry (Morus alba L.) leaf improve skeletal muscle mitochondrial function by activating AMPK in type 2 diabetes
PMCID: Pubmed No.:31639486
Autophagy mediated by JNK1 resists apoptosis through TRAF3 degradation in osteoclastogenesis
PMCID: Pubmed No.:31654668
Mitoferrin 2 deficiency prevents mitochondrial iron overload-induced endothelial injury and alleviates atherosclerosis
PMCID: Pubmed No.:33711329
N-acetylcysteine prevents orchiectomy-induced osteoporosis by inhibiting oxidative stress and osteocyte senescence
PMCID: Pubmed No.:31396339
Pyrroloquinoline quinone prevents knee osteoarthritis by inhibiting oxidative stress and chondrocyte senescence
PMCID: Pubmed No.:30972174
Deletion of p16 prevents estrogen deficiency-induced osteoporosis by inhibiting oxidative stress and osteocyte senescence
PMCID: Pubmed No.:32194914
Mitochondrial-targeted antioxidant MitoQ provides neuroprotection and reduces neuronal apoptosis in experimental traumatic brain injury possibly via the Nrf2-ARE pathway
PMCID: Pubmed No.:30018728
Deletion of aquaporin-4 aggravates brain pathology after blocking of the meningeal lymphatic drainage
PMCID: Pubmed No.:30347264
Curcumin provides neuroprotection in model of traumatic brain injury via the Nrf2-ARE signaling pathway
PMCID: Pubmed No.:29626606
Identification and Functional Verification of MicroRNA-16 Family Targeting Intestinal Divalent Metal Transporter 1 (DMT1) in vitro and in vivo
PMCID: Pubmed No.:31316397
Docosahexaenoic acid inhibits hepatic stellate cell activation to attenuate liver fibrosis in a PPARγ-dependent manner
PMCID: Pubmed No.:31437794
1-Methylnicotinamide attenuates lipopolysaccharide-induced cognitive deficits via targeting neuroinflammation and neuronal apoptosis
PMCID: Pubmed No.:31639616
Protective effects of tauroursodeoxycholic acid on lipopolysaccharide-induced cognitive impairment and neurotoxicity in mice
PMCID: Pubmed No.:30986644
Geniposide, a sonic hedgehog signaling inhibitor, inhibits the activation of hepatic stellate cell
PMCID: Pubmed No.:31005778
Effect of silencing HIF-1α gene on testicle spermatogenesis function in varicocele rats
PMCID: Pubmed No.:31377879
Nagilactone D ameliorates experimental pulmonary fibrosis in vitro and in vivo via modulating TGF-β/Smad signaling pathway
PMCID: Pubmed No.:31953203
Chitosan-gold nanoparticles mediated gene delivery of c-myb facilitates osseointegration of dental implants in ovariectomized rat
PMCID: Pubmed No.:30307328
PPAR-γ Promotes Hematoma Clearance through Haptoglobin-Hemoglobin-CD163 in a Rat Model of Intracerebral Hemorrhage
PMCID: Pubmed No.:30123388
Thiamine ameliorates inflammation of the ruminal epithelium of Saanen goats suffering from subacute ruminal acidosis
PMCID: Pubmed No.:31837780
Effect of seasonal variance on intestinal epithelial barriers and the associated innate immune response of the small intestine of the Chinese soft-shelled turtles
PMCID: Pubmed No.:31857223
Echinocystic acid provides a neuroprotective effect via the PI3K/AKT pathway in intracerebral haemorrhage mice
PMCID: Pubmed No.:32055597
The JAK2/STAT3 pathway is involved in dexmedetomidine-induced myocardial protection in rats undergoing cardiopulmonary bypass
PMCID: Pubmed No.:32395527
Phenotypic characterization of a novel type 2 diabetes animal model in a SHANXI MU colony of Chinese hamsters
PMCID: Pubmed No.:31025261
Protective effect of bone marrow mesenchymal stem cell-derived exosomes against the reproductive toxicity of cyclophosphamide is associated with the p38MAPK/ERK and AKT signaling pathways
PMCID: Pubmed No.:33565424
HSC-specific knockdown of GGPPS alleviated CCl4-induced chronic liver fibrosis through mediating RhoA/Rock pathway
PMCID: Pubmed No.:31105844
Synergistic protection of tetramethylpyrazine phosphate and borneol on brain microvascular endothelium cells injured by hypoxia
PMCID: Pubmed No.:31105826
Echinocystic acid, a natural plant extract, alleviates cerebral ischemia/reperfusion injury via inhibiting the JNK signaling pathway
PMCID: Pubmed No.:31425684
6-Gingerol attenuates microglia-mediated neuroinflammation and ischemic brain injuries through Akt-mTOR-STAT3 signaling pathway
PMCID: Pubmed No.:32681941
Bacteroides fragilis alleviates the symptoms of lupus nephritis via regulating CD1d and CD86 expressions in B cells
PMCID: Pubmed No.:32721450
Quercetin reverses chronic unpredictable mild stress-induced depression-like behavior in vivo by involving nuclear factor-E2-related factor 2
PMCID: Pubmed No.:34529966
Naringenin attenuates endoplasmic reticulum stress, reduces apoptosis, and improves functional recovery in experimental traumatic brain injury
PMCID: Pubmed No.:34324877
Sestrin2 overexpression attenuates focal cerebral ischemic injury in rat by increasing Nrf2/HO-1 pathway-mediated angiogenesis
PMCID: Pubmed No.:31085280
Piperlongumine Inhibits Zika Virus Replication In vitro and Promotes Up-Regulation of HO-1 Expression, Suggesting An Implication of Oxidative Stress
PMCID: Pubmed No.:33185862
Human umbilical cord mesenchymal stem cells alleviate inflammatory bowel disease by inhibiting ERK phosphorylation in neutrophils
PMCID: Pubmed No.:31938969
Ketamine ameliorates oxidative stress-induced apoptosis in experimental traumatic brain injury via the Nrf2 pathway
PMCID: Pubmed No.:29713142
Combined effect of vitamin C and vitamin D 3 on intestinal epithelial barrier by regulating Notch signaling pathway
PMCID: Pubmed No.:33964955
Increase in P-glycoprotein levels in the blood-brain barrier of partial portal vein ligation /chronic hyperammonemia rats is medicated by ammonia/reactive oxygen species/ERK1/2 activation: In vitro and in vivo studies
PMCID: Pubmed No.:30639310
A novel TGF-β receptor II mutation (I227T/N236D) promotes aggressive phenotype of oral squamous cell carcinoma via enhanced EGFR signaling
PMCID: Pubmed No.:33246423
Long Noncoding RNA N-BLR Upregulates the Migration and Invasion of Gastric Adenocarcinoma
PMCID: Pubmed No.:30970439
Atorvastatin ameliorates depressive behaviors and neuroinflammatory in streptozotocin-induced diabetic mice
PMCID: Pubmed No.:31786648
Cholecystokinin-8 attenuates methamphetamine-induced inflammatory activation of microglial cells through CCK2 receptor
PMCID: Pubmed No.:32916201
Ginsenoside Rh2 inhibits HeLa cell energy metabolism and induces apoptosis by upregulating voltage‑dependent anion channel 1
PMCID: Pubmed No.:33000213
Inhibition of TREM-1 attenuates early brain injury after subarachnoid hemorrhage via downregulation of p38MAPK/MMP-9 and preservation of ZO-1
PMCID: Pubmed No.:30910643
Osteopontin promotes cancer cell drug resistance, invasion, and lactate production and is associated with poor outcome of patients with advanced non-small-cell lung cancer
PMCID: Pubmed No.:30275702
Rhein attenuates PTZ‑induced epilepsy and exerts neuroprotective activity via inhibition of the TLR4-NFκB signaling pathway
PMCID: Pubmed No.:34090938
The Involvement of Mitochondrial Biogenesis in Selenium Reduced Hyperglycemia-Aggravated Cerebral Ischemia Injury
PMCID: Pubmed No.:32447509
Interleukins 6/8 and cyclooxygenase‐2 release and expressions are regulated by oxidative stress‐JAK2/STAT3 signaling pathway in human bronchial epithelial cells exposed to particulate matter ≤2.5 μm
PMCID: Pubmed No.:32212198
RNPS1 inhibition aggravates ischemic brain injury and promotes neuronal death
PMCID: Pubmed No.:31831174
DKK1 is epigenetically downregulated by promoter methylation and inhibits bile acid-induced gastric intestinal metaplasia
PMCID: Pubmed No.:31952791
FoxO1-mediated autophagy plays an important role in the neuroprotective effects of hydrogen in a rat model of vascular dementia
PMCID: Pubmed No.:29885845
Islet Transplantation Attenuating Testicular Injury in Type 1 Diabetic Rats Is Associated with Suppression of Oxidative Stress and Inflammation via Nrf-2/HO-1 and NF-κB Pathways
PMCID: Pubmed No.:31583254
The Long Noncoding RNA LOXL1-AS1 Promotes the Proliferation, Migration, and Invasion in Hepatocellular Carcinoma
PMCID: Pubmed No.:33381389
Pioglitazone prevents cholesterol gallstone formation through the regulation of cholesterol homeostasis in guinea pigs with a lithogenic diet
PMCID: Pubmed No.:31829191
Electromagnetic Fields Ameliorate Insulin Resistance and Hepatic Steatosis by Modulating Redox Homeostasis and SREBP-1c Expression in db/db Mice
PMCID: Pubmed No.:33727836
Chotosan ameliorates cognitive impairment and hippocampus neuronal loss in experimental vascular dementia via activating the Nrf2-mediated antioxidant pathway
PMCID: Pubmed No.:30642751
Schaftoside ameliorates oxygen glucose deprivation-induced inflammation associated with the TLR4/Myd88/Drp1-related mitochondrial fission in BV2 microglia cells
PMCID: Pubmed No.:30528467
Chlorogenic acid prevents paraquat-induced apoptosis via Sirt1-mediated regulation of redox and mitochondrial function
PMCID: Pubmed No.:31106605
Research on the establishment of chronic stress‐induced premature ovarian failure the rat model and effects of Chinese medicine Muniziqi treatment
PMCID: Pubmed No.:30512210
Magnesium isoglycyrrhizinate suppresses LPS-induced inflammation and oxidative stress through inhibiting NF-κB and MAPK pathways in RAW264.7 cells
PMCID: Pubmed No.:30617018
Thioredoxin-interacting protein mediates mitochondrion-dependent apoptosis in early brain injury after subarachnoid hemorrhage
PMCID: Pubmed No.:29905889
Metabolism of selected model substrates and insecticides by recombinant CYP6FD encoded by its gene predominately expressed in the brain of Locusta migratoria
PMCID: Pubmed No.:31400777
Activation of RAW264.7 macrophage by Exopolysaccharide from Aphanothece halaphytica (EPSAH) and the underlying mechanisms
PMCID: Pubmed No.:32083746
Cytoskeletal alteration modulates cancer cell invasion through RhoA-YAP signaling in stromal fibroblasts
PMCID: Pubmed No.:30921404
Cardiopulmonary Bypass Induces Acute Lung Injury via the High-Mobility Group Box 1/Toll-Like Receptor 4 Pathway
PMCID: Pubmed No.:33062073
Spinal miR-34a regulates inflammatory pain by targeting SIRT1 in complete Freund's adjuvant mice
PMCID: Pubmed No.:31296380
Mussel adhesive protein blended with gelatin loaded into nanotube titanium dental implants enhances osseointegration
PMCID: Pubmed No.:32557198
Contribution of Hepatic Retinaldehyde Dehydrogenase Induction to Impairment of Glucose Metabolism by High‐Fat‐Diet Feeding in C57BL/6J Mice
PMCID: Pubmed No.:29753302
Alterations in the Neurobehavioral Phenotype and ZnT3/CB-D28k Expression in the Cerebral Cortex Following Lithium-Pilocarpine-Induced Status Epilepticus: the Ameliorative Effect of Leptin
PMCID: Pubmed No.:29687372
Upregulated microRNA-423-5p promotes oxidative stress through targeting glutathione S-transferase mu 1 in asthenozoospermia
PMCID: Pubmed No.:33507590
4‐Sulfonyloxy/alkoxy benzoxazolone derivatives with high anti‐inflammatory activities: Synthesis, biological evaluation, and action mechanism via p38/ERK‐NF‐κB/iNOS pathway
PMCID: Pubmed No.:32915501
Gambogenic acid triggers apoptosis in human nasopharyngeal carcinoma CNE-2Z cells by activating volume-sensitive outwardly rectifying chloride channel
PMCID: Pubmed No.:30654125
Activation of the Nrf2/HO-1 signaling pathway contributes to the protective effects of baicalein against oxidative stress-induced DNA damage and apoptosis in HEI193 Schwann cells
PMCID: Pubmed No.:30662338
The protective effect of small peptides from Periplaneta americana on hydrogen peroxide–induced apoptosis of granular cells
PMCID: Pubmed No.:34155600
Design, Synthesis, Molecular Docking, and Biological Evaluation of New Emodin Anthraquinone Derivatives as Potential Antitumor Substances
PMCID: Pubmed No.:32627416
The role of E2F1-topoIIβ signaling in regulation of cell cycle exit and neuronal differentiation of human SH-SY5Y cells
PMCID: Pubmed No.:30216786
Inhibition of N822K T>A mutation-induced constitutive c-KIT activation in AML cells triggers apoptotic and autophagic pathways leading to death
PMCID: Pubmed No.:31217744
Neuroepithelial Cell Transforming Gene 1 Acts as an Oncogene and Is Mediated by miR-22 in Human Non-Small-Cell Lung Cancer
PMCID: Pubmed No.:32420320
PRDX2 Promotes the Proliferation and Metastasis of Non-Small Cell Lung Cancer In Vitro and In Vivo
PMCID: Pubmed No.:32908916
SS31 attenuates oxidative stress and neuronal apoptosis in early brain injury following subarachnoid hemorrhage possibly by the mitochondrial pathway
PMCID: Pubmed No.:31785308
Overexpression of adiponectin alleviates intracerebral hemorrhage-induced brain injury in rats via suppression of oxidative stress
PMCID: Pubmed No.:29870775
Paeoniflorin exerts neuroprotective effects by modulating the M1/M2 subset polarization of microglia/macrophages in the hippocampal CA1 region of vascular dementia rats via cannabinoid receptor 2
PMCID: Pubmed No.:29560022
MicroRNA-1297 inhibits proliferation and promotes apoptosis in gastric cancer cells by downregulating CDC6 expression
PMCID: Pubmed No.:31419217
Haem relieves hyperoxia-mediated inhibition of HMEC-1 cell proliferation, migration and angiogenesis by inhibiting BACH1 expression
PMCID: Pubmed No.:33632168
Effect of histone demethylase KDM5A on the odontogenic differentiation of human dental pulp cells
PMCID: Pubmed No.:32208897
The novel GLP-1/GIP dual receptor agonist DA3-CH is neuroprotective in the pilocarpine-induced epileptogenesis rat model
PMCID: Pubmed No.:31121474
Post-treatment with the GLP-1 analogue liraglutide alleviate chronic inflammation and mitochondrial stress induced by Status epilepticus
PMCID: Pubmed No.:29549796
The microglial activation profile and associated factors after experimental spinal cord injury in rats
PMCID: Pubmed No.:30275694
Systematic Administration of B Vitamins Alleviates Diabetic Pain and Inhibits Associated Expression of P2X3 and TRPV1 in Dorsal Root Ganglion Neurons and Proinflammatory Cytokines in Spinal Cord in Rats
PMCID: Pubmed No.:32104520
Phosphorylated Hsp27 prevents LPS‐induced excessive inflammation in THP‐1 cells via suppressing ROS‐mediated upregulation of CBP
PMCID: Pubmed No.:31483551
Activation of the Nrf2-ARE signal pathway after blast induced traumatic brain injury in mice
PMCID: Pubmed No.:30648894
CART mitigates oxidative stress and DNA damage in memory deficits of APP/PS1 mice via upregulating β‑amyloid metabolism‑associated enzymes
PMCID: Pubmed No.:33604684
A GLP‑1 receptor agonist attenuates human islet amyloid polypeptide‑induced autophagy and apoptosis in MIN6 cells
PMCID: Pubmed No.:30569165
Angiotensin II upregulates cyclophilin A by enhancing ROS production in rat cardiomyocytes
PMCID: Pubmed No.:30221707
The GLP-1/GIP dual-receptor agonist DA5-CH inhibits the NF-κB inflammatory pathway in the MPTP mouse model of Parkinson's disease more effectively than the GLP-1 single-receptor agonist NLY01
PMCID: Pubmed No.:34125470
KLF4 upregulation is involved in alternative macrophage activation during secondary Echinococcus granulosus infection
PMCID: Pubmed No.:31407814
Sorafenib blocks the activation of the HIF-2α/VEGFA/EphA2 pathway, and inhibits the rapid growth of residual liver cancer following high-intensity focused ultrasound therapy in vivo
PMCID: Pubmed No.:33640712
Interaction between CA repeat microsatellites and HIF1α regulated the transcriptional activity of porcine IGF1 promoter
PMCID: Pubmed No.:31673965
Bovine bta-microRNA-1271 Promotes Preadipocyte Differentiation by Targeting Activation Transcription Factor 3
PMCID: Pubmed No.:33040719
Human umbilical cord mesenchymal stem cell exosomes alleviate sepsis-associated acute kidney injury via regulating microRNA-146b expression
PMCID: Pubmed No.:32048128
MicroRNA-136-3p inhibits glioma tumorigenesis in vitro and in vivo by targeting KLF7
PMCID: Pubmed No.:32677950
Semaglutide-mediated protection against Aβ correlated with enhancement of autophagy and inhibition of apotosis
PMCID: Pubmed No.:33222922
Effect of Oleanolic Acid on Apoptosis and Autophagy of SMMC-7721 Hepatoma Cells
PMCID: Pubmed No.:32424110
Biochanin A Reduces Inflammatory Injury and Neuronal Apoptosis following Subarachnoid Hemorrhage via Suppression of the TLRs/TIRAP/MyD88/NF-κB Pathway
PMCID: Pubmed No.:29971136
Increased lactic acid content associated with extracellular matrix depletion in a porcine disc degeneration induced by superficial annular lesion
PMCID: Pubmed No.:31747924
Effects of erythropoietin for precaution of steroid-induced femoral head necrosis in rats
PMCID: Pubmed No.:30086737
Effects of claudin‑1 downregulation on the physiological processes of gallbladder cancer SGC996 cells
PMCID: Pubmed No.:30675228
Adiponectin reduces brain injury after intracerebral hemorrhage by reducing NLRP3 inflammasome expression
PMCID: Pubmed No.:31607194
Deferoxamine reduces amyloid-beta peptides genesis and alleviates neural apoptosis after traumatic brain injury
PMCID: Pubmed No.:33788818
Qingxin Kaiqiao Recipe Improves Cognitive Performance, Inhibits Apoptosis, and Reduces Pathological Deposits in APP/PS1 Double Transgenic Mice via the PI3K/Akt Pathway
PMCID: Pubmed No.:32419798
Oxidative stress and mitochondrial dysfunction of retinal ganglion cells injury exposures in long-term blue light
PMCID: Pubmed No.:33344182
Bupleurum polysaccharides ameliorated renal injury in diabetic mice associated with suppression of HMGB1-TLR4 signaling
PMCID: Pubmed No.:31526499
Allicin attenuates early brain injury after experimental subarachnoid hemorrhage in rats
PMCID: Pubmed No.:30773476
Allicin attenuates early brain injury after experimental subarachnoid hemorrhage in rats
PMCID: Pubmed No.:30773476
Trichinella spiralis muscle larvae excretory/secretory products trigger apoptosis and S-phase arrest of the non-small-cell lung cancer line A549
PMCID: Pubmed No.:32861680
Tetrahydrocurcumin Provides Neuroprotection in Experimental Traumatic Brain Injury and the Nrf2 Signaling Pathway as a Potential Mechanism
PMCID: Pubmed No.:29669346
miR-140 inhibits porcine fetal fibroblasts proliferation by directly targeting type 1 insulin-like growth factor receptor and indirectly inhibiting type 1 insulin-like growth factor receptor expression via SRY-box 4
PMCID: Pubmed No.:32054205
Aurora A inhibition disrupts chromosome condensation and spindle assembly during the first embryonic division in pigs
PMCID: Pubmed No.:32053743
Mechanism underlying the effect of SO2-induced oxidation on human skin keratinocytes
PMCID: Pubmed No.:33235076
Mechanism of H2S‑mediated ROCK inhibition of total flavones of Rhododendra against myocardial ischemia injury
PMCID: Pubmed No.:31611932
Triptolide protects against TGF‑β1‑induced pulmonary fibrosis by regulating FAK/calpain signaling
PMCID: Pubmed No.:31777561
Mogrol attenuates lipopolysaccharide (LPS)-induced memory impairment and neuroinflammatory responses in mice
PMCID: Pubmed No.:31347387
Cytotoxic effect of interleukin-8 in retinal ganglion cells and its possible mechanisms
PMCID: Pubmed No.:30140629
Administration of Donor-Derived Nonexpanded Adipose Stromal Vascular Fraction Attenuates Ischemia-Reperfusion Injury in Donation After Cardiac Death Rat Renal Transplantation
PMCID: Pubmed No.:34266654
Preliminary Study of Bone Marrow-Derived Mesenchymal Stem Cells Pretreatment With Erythropoietin in Preventing Acute Rejection After Rat Renal Transplantation
PMCID: Pubmed No.:30577280
Mild Hypothermia Protects Renal Function in Ischemia-reperfusion Kidney: An Experimental Study in Mice
PMCID: Pubmed No.:30577273
TPEN Attenuates Neural Autophagy Induced by Synaptically-released Zinc Translocation and Improves Histological Outcomes after Traumatic Brain Injury in Rats
PMCID: Pubmed No.:30143485
Hyperoside alleviated N-acetyl-para-amino-phenol-induced acute hepatic injury via Nrf2 activation
PMCID: Pubmed No.:31933721
Discovery and characterization of a novel splice variant of the p53 tumor suppressor gene in a human T cell leukemia cellline
PMCID: Pubmed No.:32509087
Aspirin-triggered lipoxin A4 attenuates lipopolysaccharide-induced acute lung injury by inhibiting activation of mitogen-activated protein kinases and NF-κB in mice
PMCID: Pubmed No.:31938370
Ethanol Extract of Hizikia fusiforme Induces Apoptosis in B16F10 Mouse Melanoma Cells through ROS-Dependent Inhibition of the PI3K/Akt Signaling Pathway
PMCID: Pubmed No.:32458633
Crucial Roles of 5-HT and 5-HT2 Receptor in Diabetes-Related Lipid Accumulation and Pro-Inflammatory Cytokine Generation in Hepatocytes
PMCID: Pubmed No.:30121645
The Protective Effect of Antioxidants in Areca Nut Extract-Induced Oral Carcinogenesis
PMCID: Pubmed No.:32856877
Nitazoxanide and related thiazolides induce cell death in cancer cells by targeting the 20S proteasome with novel binding modes
PMCID: Pubmed No.:35032461
Pan-cancer analysis, cell and animal experiments revealing TEAD4 as a tumor promoter in ccRCC
PMCID: Pubmed No.:35065165
Leaf extract of Osbeckia octandra induces apoptosis in oral squamous cell carcinoma cells
PMCID: Pubmed No.:35078428
Pyrrolidine Dithiocarbamate Might Mitigate Radiation-Induced Heart Damage at an Early Stage in Rats.
PMCID: Pubmed No.:35392554
Strongylocentrotus nudus Eggs Polysaccharide Enhances Macrophage Phagocytosis Against E.coli Infection by TLR4/STAT3 Axis.
PMCID: Pubmed No.:35370674
Norisoboldine induces the development of Treg cells by promoting fatty acid oxidation-mediated H3K27 acetylation of Foxp3
PMCID: Pubmed No.:35233835
Empagliflozin Inhibits Hepatic Gluconeogenesis and Increases Glycogen Synthesis by AMPK/CREB/GSK3β Signalling Pathway
PMCID: Pubmed No.:35299662
Protective effects of heterophyllin B against bleomycin-induced pulmonary fibrosis in mice via AMPK activation
PMCID: Pubmed No.:35283110
MCFA alleviate H2O2-induced oxidative stress in AML12 cells via the ERK1/2/Nrf2 pathway
PMCID: Pubmed No.:35262212
Activation of TGR5 Ameliorates Streptozotocin-Induced Cognitive Impairment by Modulating Apoptosis, Neurogenesis, and Neuronal Firing
PMCID: Pubmed No.:35464765
The activation of PPARγ enhances Treg responses through up-regulating CD36/CPT1-mediated fatty acid oxidation and subsequent N-glycan branching of TβRII/IL-2Rα
PMCID: Pubmed No.:35392915
The activation of PPARγ enhances Treg responses through up-regulating CD36/CPT1-mediated fatty acid oxidation and subsequent N-glycan branching of TβRII/IL-2Rα
PMCID: Pubmed No.:35392915
The effect of D-chiro-inositol on renal protection in diabetic mice
PMCID: Pubmed No.:35439732
Effects of Changes in Osmolarity on the Biological Activity of Human Normal Nucleus Pulposus Mesenchymal Stem Cells
PMCID: Pubmed No.:35502327
PGC1α-mediated fatty acid oxidation promotes TGFβ1-induced epithelial-mesenchymal transition and metastasis of nasopharyngeal carcinoma
PMCID: Pubmed No.:35452637
Eplerenone inhibits UUO-induced lymphangiogenesis and cardiac fibrosis by attenuating inflammatory injury
PMCID: Pubmed No.:35428023
H2S Protects Against Immobilization-Induced Muscle Atrophy via Reducing Oxidative Stress and Inflammation
PMCID: Pubmed No.:35464091
Metformin protects 5-Fu-induced chemotherapy oral mucositis by reducing endoplasmic reticulum stress in mice
PMCID: Pubmed No.:35405270
sTREM-1 promotes the phagocytic function of microglia to induce hippocampus damage via the PI3K–AKT signaling pathway
PMCID: Pubmed No.:35487953
Sirtuin 1 alleviates microglia-induced inflammation by modulating the PGC-1α/Nrf2 pathway after traumatic brain injury in male rats
PMCID: Pubmed No.:35487384
A study of diabetes-induced erectile dysfunction treated with human umbilical cord mesenchymal stem cells
PMCID: Pubmed No.:35415927
Fibroblast growth factor 11 inhibits foot-and-mouth disease virus gene expression and replication in vitro
PMCID: Pubmed No.:35387954
Extracellular vesicles derived from astrocyte-treated with haFGF14-154 attenuate Alzheimer phenotype in AD mice
PMCID: Pubmed No.:35664060
Brain-targeted heptapeptide-loaded exosomes attenuated ischemia–reperfusion injury by promoting the transfer of healthy mitochondria from astrocytes to neurons
PMCID: Pubmed No.:35606779
Sublytic C5b-9 Induces CCL3/4 Production and Macrophage Accumulation in Thy-1N Rats via PKC-α/p65/IRF-8 Axis
PMCID: Pubmed No.:35637950
Neonatal inflammation via persistent TGF-β1 downregulation decreases GABAAR expression in basolateral amygdala leading to the imbalance of the local excitation-inhibition circuits and anxiety-like phenotype in adult mice
PMCID: Pubmed No.:35513229
An Emerging Role of Proanthocyanidins on Psoriasis: Evidence from a Psoriasis-Like Mouse Model
PMCID: Pubmed No.:35720176
The secretion of sIgA and dendritic cells activation in the intestinal of cyclophosphamide-induced immunosuppressed mice are regulated by Alhagi honey polysaccharides
PMCID: Pubmed No.:35675749
BCR/ABL1ΔE7-8-9 isoform contributes to tyrosine kinase inhibitor resistance in chronic myeloid leukemia
PMCID: Pubmed No.:35686657
UVB-induced SFRP1 methylation potentiates skin damage by promoting cell apoptosis and DNA damage
PMCID: Pubmed No.:35657114
Effect of miR-101 on the Proliferation and Apoptosis of Goat Hair Follicle Stem Cells
PMCID: Pubmed No.:35741797
Chitosan Oligosaccharide Inhibits the Synthesis of Milk Fat in Bovine Mammary Epithelial Cells through AMPK-Mediated Downstream Signaling Pathway
PMCID: Pubmed No.:35804595
High levels of TDO2 in relation to pro-inflammatory cytokines in synovium and synovial fluid of patients with osteoarthritis
PMCID: Pubmed No.:35733134
Sirt1 overexpression improves senescence-associated pulmonary fibrosis induced by vitamin D deficiency through downregulating IL-11 transcription
PMCID: Pubmed No.:35906886
Oncogenic TRIB2 interacts with and regulates PKM2 to promote aerobic glycolysis and lung cancer cell procession
PMCID: Pubmed No.:35790734
LncRNA-84277 is involved in chronic pain-related depressive behaviors through miR-128-3p/SIRT1 axis in central amygdala
PMCID: Pubmed No.:35959106
Enterobacterial LPS-inducible LINC00152 is regulated by histone lactylation and promotes cancer cells invasion and migration
PMCID: Pubmed No.:35959377
MBD1/HDAC3-miR-5701-FGFR2 axis promotes the development of gastric cancer
PMCID: Pubmed No.:35876658
Effect of Probiotic Fungi against Cognitive Impairment in Mice via Regulation of the Fungal Microbiota–Gut–Brain Axis
PMCID: Pubmed No.:35833673
lncKRT16P6 promotes tongue squamous cell carcinoma progression by sponging miR‑3180 and regulating GATAD2A expression
PMCID: Pubmed No.:35904180
miR-301a-3p promotes hepatic stellate cells activation and liver fibrogenesis via regulating PTEN/PDGFR-β
PMCID: Pubmed No.:35834952
Semaglutide Protects against 6-OHDA Toxicity by Enhancing Autophagy and Inhibiting Oxidative Stress
PMCID: Pubmed No.:35873704
Differential proteome response to H5N1 highly pathogenic avian influenza (HPAI) viruses infection in duck.
PMCID: Pubmed No.:36059479
PPAR-γ alleviates the inflammatory response in TNF-α-induced fibroblast-like synoviocytes by binding to p53 in rheumatoid arthritis
PMCID: Pubmed No.:35918412
Construction of Fzd6Q152E mice through CRISPR/Cas9 technology and their reproduction and identification
PMCID: Pubmed No.:35980530
miR-150 promotes progressive T cell differentiation via inhibiting FOXP1 and RC3H1
PMCID: Pubmed No.:35999072
Effects of neuron autophagy induced by arsenic and fluoride on spatial learning and memory in offspring rats
PMCID: Pubmed No.:36087721
The protective effect of proanthocyanidins on the psoriasis-like cell models via PI3K/AKT and HO-1
PMCID: Pubmed No.:36178125
Exploring the synergic mechanism of Ligusticum striatum DC. and borneol in attenuating BMECs injury and maintaining tight junctions against cerebral ischaemia based on the HIF-1α/VEGF signalling pathway
PMCID: Pubmed No.:36183951
Ginseng polysaccharide attenuates red blood cells oxidative stress injury by regulating red blood cells glycolysis and liver gluconeogenesis
PMCID: Pubmed No.:36122792
Oridonin ameliorates caspase-9-mediated brain neuronal apoptosis in mouse with ischemic stroke by inhibiting RIPK3-mediated mitophagy
PMCID: Pubmed No.:36216897
β-catenin ISGylation promotes lipid deposition and apoptosis in ethanol-stimulated liver injury models
PMCID: Pubmed No.:36259544
Cattle Encephalon Glycoside and Ignotin Attenuates Aβ1-42-Mediated Neurotoxicity by Preventing NLRP3 Inflammasome Activation and Modulating Microglial Polarization via TLR4/NF-κB Signaling Pathway
PMCID: Pubmed No.:36214996
Aerobic Glycolysis Induced by mTOR/HIF-1α Promotes Early Brain Injury After Subarachnoid Hemorrhage via Activating M1 Microglia
PMCID: Pubmed No.:36385451
Phosphorylation of Enteroviral 2Apro at Ser/Thr125 Benefits Its Proteolytic Activity and Viral Pathogenesis
PMCID: Pubmed No.:36511115
Maternal circadian disruption before pregnancy impairs the ovarian function of female offspring in mice
PMCID: Pubmed No.:36572306
P38γ modulates the lipid metabolism in non-alcoholic fatty liver disease by regulating the JAK–STAT signaling pathway
PMCID: Pubmed No.:36527390
Halofuginone ameliorates systemic lupus erythematosus by targeting Blk in myeloid-derived suppressor cells
PMCID: Pubmed No.:36493694
SS31 Confers Cerebral Protection by Reversing Mitochondrial Dysfunction in Early Brain Injury Following Subarachnoid Hemorrhage, via the Nrf2- and PGC-1α-Dependent Pathways
PMCID: Pubmed No.:36574150
Mycobacterium tuberculosis PE_PGRS1 promotes mycobacteria intracellular survival via reducing the concentration of intracellular free Ca2+ and suppressing endoplasmic reticulum stress
PMCID: Pubmed No.:36584479
The functional link between TCTP and Drsl1 in deltamethrin-stressed Drosophila Kc cells
PMCID: Pubmed No.:36464172
Neuroprotective effect of hyperoside in MPP+/MPTP -induced dopaminergic neurodegeneration
PMCID: Pubmed No.:36576692
Small Molecule Compound K-7174 Attenuates Neuropsychiatric Manifestations in Lupus-prone Mice
PMCID: Pubmed No.:36521514
Multi-omics analysis unravels positive effect of rotenone on the cordycepin biosynthesis in submerged fermentation of Cordyceps militaris
PMCID: Pubmed No.:36746212
Baicalin Nanocomplexes with an In Situ-Forming Biomimetic Gel Implant for Repair of Calvarial Bone Defects via Localized Sclerostin Inhibition
PMCID: Pubmed No.:36753285
A novel sorbicillinoid compound as a potent anti-inflammation agent through inducing NLRP3 protein degradation
PMCID: Pubmed No.:36788033
Repurposing Axl Kinase Inhibitors for the Treatment of Respiratory Syncytial Virus Infection
PMCID: Pubmed No.:36853000
Cytoplasmic localization of IRF5 induces Wnt5a/E-cadherin degradation and promotes gastric cancer cells metastasis
PMCID: Pubmed No.:36782048
MiR-146a-5p Contributes to Microglial Polarization Transitions Associated With AGEs
PMCID: Pubmed No.:36780120
DIFFERENTIATED EMBRYONIC CHONDROCYTE EXPRESSED GENE-1 IS A CENTRAL SIGNALING COMPONENT IN THE DEVELOPMENT OF COLLAGEN-INDUCED RHEUMATOID ARTHRITIS
PMCID: Pubmed No.:36739947
Shikonin improves pulmonary vascular remodeling in monocrotaline‑induced pulmonary arterial hypertension via regulation of PKM2
PMCID: Pubmed No.:36734266
Promotion of ferroptosis in head and neck cancer with divalent metal transporter 1 inhibition or salinomycin
PMCID: Pubmed No.:36890422
Silencing MARCH2 Inhibits the Invasion, Migration, and EMT Transformation of Human Colorectal Cancer SW480 Cells
PMCID: Pubmed No.:36959742
Microglial CD11b Knockout Contributes to Axonal Debris Clearance and Axonal Degradation Attenuation via IGF-1 After Acute Optic Nerve Injury
PMCID: Pubmed No.:37145604
Interleukin-37 inhibits desmoglein-3 endocytosis and keratinocyte dissociation via upregulation of Caveolin-1 and inhibition of the STAT3 pathway
PMCID: Pubmed No.:37262304
Silencing of circCacna1c Inhibits ISO-Induced Cardiac Hypertrophy through miR-29b-2-5p/NFATc1 Axis
PMCID: Pubmed No.:37371137
Wwl70-induced ABHD6 inhibition attenuates memory deficits and pathological phenotypes in APPswe/PS1dE9 mice
PMCID: Pubmed No.:37480972
Decidual macrophages derived NO downregulates PD-L1 in trophoblasts leading to decreased Treg cells in recurrent miscarriage
PMCID: Pubmed No.:37520550
17-DMAG ameliorates neuroinflammation and BBB disruption via SOX5 mediated PI3K/Akt pathway after intracerebral hemorrhage in rats
PMCID: Pubmed No.:37517381
A newly-synthesized compound CP-07 alleviates microglia-mediated neuroinflammation and ischemic brain injury via inhibiting STAT3 phosphorylation
PMCID: Pubmed No.:37408577
Estrogen increases the expression of BKCa and impairs the contraction of colon smooth muscle via upregulation of sphingosine kinase 1
PMCID: Pubmed No.:37642352
Hydrogen Sulfide Prevents LPS-Induced Depression-like Behavior through the Suppression of NLRP3 Inflammasome and Pyroptosis and the Improvement of Mitochondrial Function in the Hippocampus of Mice
PMCID: Pubmed No.:37626978
0.01% Hypochlorous Acid Treats Aspergillus fumigatus Keratitis in Rats by Reducing Fungal Load and Inhibiting the Inflammatory Response
PMCID: Pubmed No.:37531113
C3N nanodots inhibits Aβ peptides aggregation pathogenic path in Alzheimer’s disease
PMCID: Pubmed No.:37714837
Exo-miR-1290-induced by COX-2 overexpression promotes cancer-associated fibroblasts activation and tumor progression by CUL3-Nrf2 pathway in lung adenocarcinoma
PMCID: Pubmed No.:37723559
Targeting SDCBP2 in acute myeloid leukemia
PMCID: Pubmed No.:37714445
GSDME in Endothelial Cells: Inducing Vascular Inflammation and Atherosclerosis via Mitochondrial Damage and STING Pathway Activation
PMCID: Pubmed No.:37761020
Resveratrol ameliorates diabetic encephalopathy through PDE4D/PKA/Drp1 signaling
PMCID: Pubmed No.:37722608
Hippocampus protection from apoptosis by Baicalin in a LiCl-pilocarpine-induced rat status epilepticus model through autophagy activation
PMCID: Pubmed No.:37771639
miR-199a and miR-199b facilitate diffuse gastric cancer progression by targeting Frizzled-6
PMCID: Pubmed No.:37838767
Brassica oleracea L. extract ameliorates isoproterenol-induced myocardial injury by regulating HIF-1α-mediated glycolysis
PMCID: Pubmed No.:37907131
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.
Price/Size :
USD 368/1mg/vial
Tips:
For phospho antibody, we provide phospho peptide(0.5mg) and non-phospho peptide(0.5mg).Describe :
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.Formula:
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.
Storage:
The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C.
Note :
This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.