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β-Actin (4D3) monoclonal antibody BS6007M
  • Western blot (WB) analysis of β-Actin (4D3) mAb at 1:5000-1:20000 dilution Lane1:The Lung tissue lysate of Mouse(20ug) Lane2:The Lung tissue lysate of Rat(20ug) Lane3:H9C2 whole cell lysate(20ug) Lane4:CT26 whole cell lysate(20ug) Lane5:L02 whole cell lysate(20ug) Lane6:HEK293T whole cell lysate(20ug)
Product Nameβ-Actin (4D3) monoclonal antibody
Catalog No.BS6007M
Swiss-ProtN/A
Host Mouse
ReactivityHuman,Mouse,Rat,zebrafish,Pig,Chicken,Odontobutis obscurus
ApplicationsWB IHC IF IP
Application_allWB: 1:5000~1:20000 IHC: 1:100~1:1000 IF: 1:100~1:500 IP: 1:100~500
BiowMW~ 42 kDa
Alternative NameActin, cytoplasmic 1; Beta-actin; Actin, cytoplasmic 1, N-terminally processed; ACTB; Actin-β; Beta actin;
Purification&PurityThe antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
ConjugateUnconjugated
ModificationUnmodified
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50ul $208
100ul $358
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Product Name :
β-Actin (4D3) monoclonal antibody
Background :
Actin, a ubiquitous eukaryotic protein, is the major component of the cytoskeleton. At least six isoforms are known in mammals. Nonmuscle β- and γ-actin, also known as cytoplasmic actin, are predominantly expressed in nonmuscle cells, controlling cell structure and motility. α-cardiac and α-skeletal actin are expressed in striated cardiac and skeletal muscles, respectively; two smooth muscle actins, α- and γ-actin, are found primarily in vascular smooth muscle and enteric smooth muscle, respectively. These actin isoforms regulate the contractile potential of muscle cells.
Product :
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :
β-Actin (4D3) detects endogenous levels of β-actin protein.
Immunogen :
Recombinant full length Human β-Actin.
Conjugate :
Unconjugated
Modification :
Unmodified
  • Western blot (WB) analysis of β-Actin (4D3) mAb at 1:5000-1:20000 dilution Lane1:The Lung tissue lysate of Mouse(20ug) Lane2:The Lung tissue lysate of Rat(20ug) Lane3:H9C2 whole cell lysate(20ug) Lane4:CT26 whole cell lysate(20ug) Lane5:L02 whole cell lysate(20ug) Lane6:HEK293T whole cell lysate(20ug)
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migration and induces apoptosis in diffuse large B cell lymphoma PMCID:    Pubmed No.:31694672 Porcine IGF-1R synonymous mutations in the intracellular domain affect cell proliferation and alter kinase activity PMCID:    Pubmed No.:32109480 Porcine IGF1 synonymous mutation alter gene expression and protein binding affinity with IGF1R PMCID:    Pubmed No.:29738863 The stemness of hepatocytes is maintained by high levels of lipopolysaccharide via YAP1 activation PMCID:    Pubmed No.:34112239 Human Cancer Cells Sense Cytosolic Nucleic Acids Through the RIG-I–MAVS Pathway and cGAS–STING Pathway PMCID:    Pubmed No.:33490069 A Novel Function of Mitochondrial Phosphoenolpyruvate Carboxykinase as a Regulator of Inflammatory Response in Kupffer Cells. PMCID:    Pubmed No.:34970539 Pyrroloquinoline Quinone Prevents Estrogen Deficiency-Induced Osteoporosis by Inhibiting Oxidative Stress and Osteocyte Senescence PMCID:    Pubmed No.:30662347 Diastereoisomer-specific neurotoxicity of hexabromocyclododecane in human SH-SY5Y neuroblastoma cells PMCID:    Pubmed No.:31200309 PKCα mediated by the PI3K/Akt-FOXA1 cascade facilitates cypermethrin-induced hyperthyroidism PMCID:    Pubmed No.:33250241 Comparative Transcriptome Analysis Reveals the Protective Mechanism of Glycyrrhinic Acid for Deoxynivalenol-Induced Inflammation and Apoptosis in IPEC-J2 Cells PMCID:    Pubmed No.:33163144 Theaflavin 3, 3-Digallate Delays Ovarian Aging by Improving Oocyte Quality and Regulating Granulosa Cell Function PMCID:    Pubmed No.:34925699 Impaired Autophagy Induced by oxLDL/β2GPI/anti-β2GPI Complex through PI3K/AKT/mTOR and eNOS Signaling Pathways Contributes to Endothelial Cell Dysfunction PMCID:    Pubmed No.:34221236 Human urinary kininogenase reduces the endothelial injury by inhibiting Pyk2/MCU pathway PMCID:    Pubmed No.:34543986 Discovery of novel 3-hydroxyandrosta-5,7-Diene-17-Carboxylic acid derivatives as anti-inflammatory bowel diseases (IBD) agents PMCID:    Pubmed No.:33933753 PIM1 kinase promotes cell proliferation, metastasis and tumor growth of lung adenocarcinoma by potentiating the c-MET signaling pathway PMCID:    Pubmed No.:30583073 Association between ARID2 and RAS-MAPK pathway in intellectual disability and short stature PMCID:    Pubmed No.:33051312 Dendritic cells-derived interferon-λ1 ameliorated inflammatory bone destruction through inhibiting osteoclastogenesis PMCID:    Pubmed No.:32488049 Recombinant milk fat globule-EGF factor-8 reduces apoptosis via integrin β3/FAK/PI3K/AKT signaling pathway in rats after traumatic brain injury PMCID:    Pubmed No.:30154436 Isoform specific FBXW7 mediates NOTCH1 Abruptex mutation C1133Y deregulation in oral squamous cell carcinoma PMCID:    Pubmed No.:32792479 Heat stress affects fetal brain and intestinal function associated with the alterations of placental barrier in late pregnant mouse PMCID:    Pubmed No.:34695613 Effect of chlorogenic acid on alleviating inflammation and apoptosis of IPEC-J2 cells induced by deoxyniyalenol PMCID:    Pubmed No.:32961488 Nrf2 Down-Regulation by Camptothecin Favors Inhibiting Invasion, Metastasis and Angiogenesis in Hepatocellular Carcinoma PMCID:    Pubmed No.:34178646 Neuroprotective effects of INT-777 against Aβ1–42-induced cognitive impairment, neuroinflammation, apoptosis, and synaptic dysfunction in mice PMCID:    Pubmed No.:29935310 Sirtuin 1 alleviates diabetic neuropathic pain by regulating synaptic plasticity of spinal dorsal horn neurons PMCID:    Pubmed No.:30649099 Bmi1 Overexpression in Mesenchymal Stem Cells Exerts Antiaging and Antiosteoporosis Effects by Inactivating p16/p19 Signaling and Inhibiting Oxidative Stress PMCID:    Pubmed No.:30895687 Upregulated osterix promotes invasion and bone metastasis and predicts for a poor prognosis in breast cancer PMCID:    Pubmed No.:30631043 Suppressing the Na + /H + exchanger 1: a new sight to treat depression PMCID:    Pubmed No.:31068571 Alpinetin exerts anti-colitis efficacy by activating AhR, regulating miR-302/DNMT-1/CREB signals, and therefore promoting Treg differentiation PMCID:    Pubmed No.:30166541 LYW-6, a novel cryptotanshinone derived STAT3 targeting inhibitor, suppresses colorectal cancer growth and metastasis PMCID:    Pubmed No.:31982491 Sinusoidal Electromagnetic Fields Increase Peak Bone Mass in Rats by Activating Wnt10b/β‐Catenin in Primary Cilia of Osteoblasts PMCID:    Pubmed No.:30779853 Effects of Molecular Hydrogen on Methamphetamine-Induced Neurotoxicity and Spatial Memory Impairment PMCID:    Pubmed No.:31396089 Timosaponin AIII Induces G2/M Arrest and Apoptosis in Breast Cancer by Activating the ATM/Chk2 and p38 MAPK Signaling Pathways PMCID:    Pubmed No.:33628174 Empagliflozin Alleviates Hepatic Steatosis by Activating the AMPK-TET2-Autophagy Pathway in vivo and in vitro PMCID:    Pubmed No.:33551821 Piperazine-Derived α1D/1A Antagonist 1- Benzyl-N- (3-(4- (2-Methoxyphenyl) Piperazine-1-yl) Propyl) -1H- Indole-2- Carboxamide Induces Apoptosis in Benign Prostatic Hyperplasia Independently of α1-Adrenoceptor Blocking PMCID:    Pubmed No.:33584271 Puerarin Prevents Acute Liver Injury via Inhibiting Inflammatory Responses and ZEB2 Expression PMCID:    Pubmed No.:34421621 Neuroprotective Effects of Shenqi Fuzheng Injection in a Transgenic SOD1-G93A Mouse Model of Amyotrophic Lateral Sclerosis PMCID:    Pubmed No.:34737697 Angelicin Alleviates Post-Trauma Osteoarthritis Progression by Regulating Macrophage Polarization via STAT3 Signaling Pathway PMCID:    Pubmed No.:34177582 PTEN Methylation Promotes Inflammation and Activation of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis PMCID:    Pubmed No.:34305608 Functions of resolvin D1-ALX/FPR2 receptor interaction in the hemoglobin-induced microglial inflammatory response and neuronal injury PMCID:    Pubmed No.:32795323 Actin polymerization state regulates osteogenic differentiation in human adipose-derived stem cells PMCID:    Pubmed No.:33858321 FasL-PDPK1 Pathway Promotes the Cytotoxicity of CD8 + T Cells During Ischemic Stroke PMCID:    Pubmed No.:32036560 Ambient PM2.5 caused cardiac dysfunction through FoxO1-targeted cardiac hypertrophy and macrophage-activated fibrosis in mice PMCID:    Pubmed No.:31978653 Electroacupuncture Pretreatment Prevents Cognitive Impairment Induced by Cerebral Ischemia–Reperfusion via Adenosine A1 Receptors in Rats PMCID:    Pubmed No.:34413765 TBX15/miR-152/KIF2C pathway regulates breast cancer doxorubicin resistance via promoting PKM2 ubiquitination PMCID:    Pubmed No.:34663310 Novel Regulatory Roles of Wnt1 in Infection-Associated Colorectal Cancer PMCID:    Pubmed No.:29626750 Cytoplasmic eIF6 promotes OSCC malignant behavior through AKT pathway PMCID:    Pubmed No.:34922580 linc00968 inhibits the tumorigenesis and metastasis of lung adenocarcinoma via serving as a ceRNA against miR-9-5p and increasing CPEB3 PMCID:    Pubmed No.:33159015 linc00968 inhibits the tumorigenesis and metastasis of lung adenocarcinoma via serving as a ceRNA against miR-9-5p and increasing CPEB3 PMCID:    Pubmed No.:33159015 Long-term every-other-day administration of DMAMCL has little effect on aging and age-associated physiological decline in mice PMCID:    Pubmed No.:31048563 Improving radio-chemotherapy efficacy of prostate cancer by co-deliverying docetaxel and dbait with biodegradable nanoparticles PMCID:    Pubmed No.:31858836 SIRT1 Decreases Emotional Pain Vulnerability with Associated CaMKIIα Deacetylation in Central Amygdala PMCID:    Pubmed No.:32005763 Nrf2 inhibition reverses resistance to GPX4 inhibitor-induced ferroptosis in head and neck cancer PMCID:    Pubmed No.:30339884 Dual Mechanisms of Novel CD73-Targeted Antibody and Antibody–Drug Conjugate in Inhibiting Lung Tumor Growth and Promoting Antitumor Immune-Effector Function PMCID:    Pubmed No.:32943546 Curcumin Sensitizes Prolactinoma Cells to Bromocriptine by Activating the ERK/EGR1 and Inhibiting the AKT/GSK-3β Signaling Pathway In Vitro and In Vivo PMCID:    Pubmed No.:34463926 Expression of a short antibody heavy chain peptide effectively antagonizes adenosine 2A receptor in vitro and in vivo PMCID:    Pubmed No.:32308059 Corydalis saxicola Bunting total alkaloids attenuate paclitaxel-induced peripheral neuropathy through PKCε/p38 MAPK/TRPV1 signaling pathway PMCID:    Pubmed No.:34281577 TGF-β1/IL-11/MEK/ERK signaling mediates senescence-associated pulmonary fibrosis in a stress-induced premature senescence model of Bmi-1 deficiency PMCID:    Pubmed No.:31959867 Alhagi honey polysaccharides attenuate intestinal injury and immune suppression in cyclophosphamide-induced mice PMCID:    Pubmed No.:34128029 JNK1 regulates RANKL-induced osteoclastogenesis via activation of a novel Bcl-2-Beclin1-autophagy pathway PMCID:    Pubmed No.:31295022 Diallyl disulfide alleviates inflammatory osteolysis by suppressing osteoclastogenesis via NF-κB–NFATc1 signal pathway PMCID:    Pubmed No.:30857415 Mogrol, an aglycone of mogrosides, attenuates ulcerative colitis by promoting AMPK activation PMCID:    Pubmed No.:33296813 Bryodulcosigenin a natural cucurbitane-type triterpenoid attenuates dextran sulfate sodium (DSS)-induced colitis in mice PMCID:    Pubmed No.:34798522 The protective effect of WKYMVm peptide on inflammatory osteolysis through regulating NF-κB and CD9/gp130/STAT3 signalling pathway PMCID:    Pubmed No.:31837208 Curcumin improves memory deficits by inhibiting HMGB1-RAGE/TLR4-NF-κB signalling pathway in APPswe/PS1dE9 transgenic mice hippocampus PMCID:    Pubmed No.:34405526 Dihydromyricetin resists inflammation-induced muscle atrophy via ryanodine receptor-CaMKK-AMPK signal pathway PMCID:    Pubmed No.:34676967 Novel Sesquiterpene Glycoside from Loquat Leaf Alleviates Type 2 Diabetes Mellitus Combined with Nonalcoholic Fatty Liver Disease by Improving Insulin Resistance, Oxidative Stress, Inflammation, and Gut Microbiota Composition PMCID:    Pubmed No.:34783554 trans 10, cis 12, but Not cis 9, trans 11 Conjugated Linoleic Acid Isomer Enhances Exercise Endurance by Increasing Oxidative Skeletal Muscle Fiber Type via Toll-like Receptor 4 Signaling in Mice PMCID:    Pubmed No.:34928153 trans 10, cis 12, but Not cis 9, trans 11 Conjugated Linoleic Acid Isomer Enhances Exercise Endurance by Increasing Oxidative Skeletal Muscle Fiber Type via Toll-like Receptor 4 Signaling in Mice PMCID:    Pubmed No.:34928153 Pulsed Electromagnetic Fields Ameliorate Skeletal Deterioration in Bone Mass, Microarchitecture, and Strength by Enhancing Canonical Wnt Signaling-Mediated Bone Formation in Rats with Spinal Cord Injury PMCID:    Pubmed No.:33108939 Butyrate Suppresses Glucose Metabolism of Colorectal Cancer Cells via GPR109a-AKT Signaling Pathway and Enhances Chemotherapy PMCID:    Pubmed No.:33855046 Resveratrol Improves Mitochondrial Biogenesis Function and Activates PGC-1α Pathway in a Preclinical Model of Early Brain Injury Following Subarachnoid Hemorrhage PMCID:    Pubmed No.:33968980 Imperatorin inhibits mitogen-activated protein kinase and nuclear factor kappa-B signaling pathways and alleviates neuroinflammation in ischemic stroke PMCID:    Pubmed No.:34674376 NR4A1 enhances MKP7 expression to diminish JNK activation induced by ROS or ER-stress in pancreatic β cells for surviving PMCID:    Pubmed No.:34088892 Effects of ALA-PDT on the Healing of Mouse Skin Wounds Infected With Pseudomonas aeruginosa and Its Related Mechanisms. PMCID:    Pubmed No.:33344449 Pyk2/MCU Pathway as a New Target for Reversing Atherosclerosis PMCID:    Pubmed No.:34026753 Selenium nanoparticles fabricated in laminarin polysaccharides solutions exert their cytotoxicities in HepG2 cells by inhibiting autophagy and promoting apoptosis PMCID:    Pubmed No.:31284007 N16 suppresses RANKL-mediated osteoclatogenesis by down-regulating RANK expression PMCID:    Pubmed No.:31751723 QKI, a miR‐200 target gene, suppresses epithelial‐to‐mesenchymal transition and tumor growth PMCID:    Pubmed No.:31026342 Paired associative stimulation improves synaptic plasticity and functional outcomes after cerebral ischemia PMCID:    Pubmed No.:31290455 Inhibition of Uncoupling Protein 2 Enhances the Radiosensitivity of Cervical Cancer Cells by Promoting the Production of Reactive Oxygen Species PMCID:    Pubmed No.:32190174 Activation of GPR55 attenuates cognitive impairment and neurotoxicity in a mouse model of Alzheimer's disease induced by Aβ1–42 through inhibiting RhoA/ROCK2 pathway PMCID:    Pubmed No.:34363866 A novel compound AB38b attenuates oxidative stress and ECM protein accumulation in kidneys of diabetic mice through modulation of Keap1/Nrf2 signaling PMCID:    Pubmed No.:31645661 Exploring the protective effects of schizandrol A in acute myocardial ischemia mice by comprehensive metabolomics profiling integrated with molecular mechanism studies PMCID:    Pubmed No.:32123298 Diabetes downregulates peptide transporter 1 in the rat jejunum: possible involvement of cholate-induced FXR activation PMCID:    Pubmed No.:32341465 Sirt1 inhibits renal tubular cell epithelial–mesenchymal transition through YY1 deacetylation in diabetic nephropathy PMCID:    Pubmed No.:32555442 Short-chain fatty acids exert opposite effects on the expression and function of p-glycoprotein and breast cancer resistance protein in rat intestine PMCID:    Pubmed No.:32555444 Fluoxetine induces lipid metabolism abnormalities by acting on the liver in patients and mice with depression PMCID:    Pubmed No.:30150788 Suppression of MIF-induced neuronal apoptosis may underlie the therapeutic effects of effective components of Fufang Danshen in the treatment of Alzheimer's disease PMCID:    Pubmed No.:29770796 Neotuberostemonine inhibits the differentiation of lung fibroblasts into myofibroblasts in mice by regulating HIF-1α signaling PMCID:    Pubmed No.:29645000 Effect of hyperglycemia on microglial polarization after cerebral ischemia-reperfusion injury in rats PMCID:    Pubmed No.:34052292 Oxymatrine alleviated hepatic lipid metabolism via regulating miR-182 in non-alcoholic fatty liver disease PMCID:    Pubmed No.:32679144 1‐L‐MT, an IDO inhibitor, prevented colitis‐associated cancer by inducing CDC20 inhibition‐mediated mitotic death of colon cancer cells PMCID:    Pubmed No.:29607498 mTORC1 promotes mineralization via p53 pathway PMCID:    Pubmed No.:33508145 Differential skeletal response in adult and aged rats to independent and combinatorial stimulation with pulsed electromagnetic fields and mechanical vibration PMCID:    Pubmed No.:31908035 Thrombin/PAR-1 activation induces endothelial damages via NLRP1 inflammasome in gestational diabetes PMCID:    Pubmed No.:32059841 Necroptosis mediated by impaired autophagy flux contributes to adverse ventricular remodeling after myocardial infarction PMCID:    Pubmed No.:32179044 Ferulic acid attenuates oxidative DNA damage and inflammatory responses in microglia induced by benzo(a)pyrene PMCID:    Pubmed No.:31699670 Inhibition of GPR17 with cangrelor improves cognitive impairment and synaptic deficits induced by Aβ1–42 through Nrf2/HO-1 and NF-κB signaling pathway in mice PMCID:    Pubmed No.:34781121 JLX001 ameliorates cerebral ischemia injury by modulating microglial polarization and compromising NLRP3 inflammasome activation via the NF-κB signaling pathway PMCID:    Pubmed No.:34740080 A novel chrysin thiazole derivative polarizes macrophages to an M1 phenotype via targeting TLR4 PMCID:    Pubmed No.:33182070 5-HT2A Receptor and 5-HT Degradation Play a Crucial Role in Atherosclerosis by Modulating Macrophage Foam Cell Formation, Vascular Endothelial Cell Inflammation, and Hepatic Steatosis PMCID:    Pubmed No.:33536397 The RhoA/ROCK pathway mediates high glucose-induced cardiomyocyte apoptosis via oxidative stress, JNK, and p38MAPK pathways PMCID:    Pubmed No.:29745021 Serum- and glucocorticoid-inducible kinase 1 promotes insulin resistance in adipocytes via degradation of insulin receptor substrate 1 PMCID:    Pubmed No.:33724645 DNA damage checkpoint pathway modulates the regulation of skeletal growth and osteoblastic bone formation by parathyroid hormone-related peptide PMCID:    Pubmed No.:29805302 The loss of dopaminergic neurons in DEC1 deficient mice potentially involves the decrease of PI3K/Akt/GSK3β signaling PMCID:    Pubmed No.:31884423 Epothilone B prevents lipopolysaccharide-induced inflammatory osteolysis through suppressing osteoclastogenesis via STAT3 signaling pathway PMCID:    Pubmed No.:32527985 Neuromedin B modulates phosphate-induced vascular calcification PMCID:    Pubmed No.:34674793 Hsa-let-7c controls the committed differentiation of IGF-1-treated mesenchymal stem cells derived from dental pulps by targeting IGF-1R via the MAPK pathways PMCID:    Pubmed No.:29650947 A Novel Phytochemical, DIM, Inhibits Proliferation, Migration, Invasion and TNF-α Induced Inflammatory Cytokine Production of Synovial Fibroblasts From Rheumatoid Arthritis Patients by Targeting MAPK and AKT/mTOR Signal Pathway PMCID:    Pubmed No.:31396207 MFG-E8 attenuates inflammation in subarachnoid hemorrhage by driving microglial M2 polarization PMCID:    Pubmed No.:33245889 Jmjd3 is involved in the susceptibility to depression induced by maternal separation via enhancing the neuroinflammation in the prefrontal cortex and hippocampus of male rats PMCID:    Pubmed No.:32084453 Protective effects of FGF10 on neurovascular unit in a rat model of neonatal hypoxic-ischemic brain injury PMCID:    Pubmed No.:32610105 Role of TREM-1 in the development of early brain injury after subarachnoid hemorrhage PMCID:    Pubmed No.:33727099 Decursinol angelate ameliorates 12-O-tetradecanoyl phorbol-13-acetate (TPA) -induced NF-κB activation on mice ears by inhibiting exaggerated inflammatory cell infiltration, oxidative stress and pro-inflammatory cytokine production PMCID:    Pubmed No.:31351099 Anthraquinone-type inhibitor of α-glucosidase enhances glucose uptake by activating an insulin-like signaling pathway in C2C12 myotubes PMCID:    Pubmed No.:31071387 Toosendanin Shows Potent Efficacy Against Human Ovarian Cancer through Caspase-Dependent Mitochondrial Apoptotic Pathway PMCID:    Pubmed No.:34521317 Schisandrin B Attenuates Colitis-Associated Colorectal Cancer through SIRT1 Linked SMURF2 Signaling PMCID:    Pubmed No.:34632965 Chicoric Acid Improves Heart and Blood Responses to Hypobaric Hypoxia in Tibetan Yaks PMCID:    Pubmed No.:29433395 Protective effects of melatonin on sepsis-induced liver injury and dysregulation of gluconeogenesis in rats through activating SIRT1/STAT3 pathway PMCID:    Pubmed No.:31234024 Metabolomic profiling of metoprolol-induced cardioprotection in a murine model of acute myocardial ischemia PMCID:    Pubmed No.:31972362 Curcumin regulates endogenous and exogenous metabolism via Nrf2-FXR-LXR pathway in NAFLD mice PMCID:    Pubmed No.:29860219 MyoD1 suppresses cell migration and invasion by inhibiting FUT4 transcription in human gastric cancer cells PMCID:    Pubmed No.:31831855 LncRNA AK077216 promotes RANKL‐induced osteoclastogenesis and bone resorption via NFATc1 by inhibition of NIP45 PMCID:    Pubmed No.:30132869 Long Noncoding RNA ANRIL Supports Proliferation of Adult T-Cell Leukemia Cells through Cooperation with EZH2 PMCID:    Pubmed No.:30258009 Resolvin D1 Attenuates Innate Immune Reactions in Experimental Subarachnoid Hemorrhage Rat Model PMCID:    Pubmed No.:33411245 NR4A1 counteracts JNK activation incurred by ER stress or ROS in pancreatic β‐cells for protection PMCID:    Pubmed No.:33124187 Alpha lipoic acid inhibits oxidative stress‐induced apoptosis by modulating of Nrf2 signalling pathway after traumatic brain injury PMCID:    Pubmed No.:30989783 PTEN negatively regulates the expression of pro-inflammatory cytokines and chemokines of fibroblast-like synoviocytes in adjuvant-induced arthritis PMCID:    Pubmed No.:31842626 Emodin prevents renal ischemia-reperfusion injury via suppression of CAMKII/DRP1-mediated mitochondrial fission PMCID:    Pubmed No.:34793771 Hippocampal SIRT1 improves cognitive impairment by deacetylating tau protein in diabetic models PMCID:    Pubmed No.:34861210 A pentacyclic triterpene derivative possessing polyhydroxyl ring A suppresses growth of HeLa cells by reactive oxygen species-dependent NF-κB pathway PMCID:    Pubmed No.:30153443 Iso-suillin-induced DNA damage leading to cell cycle arrest and apoptosis arised from p53 phosphorylation in A549 cells PMCID:    Pubmed No.:34217708 Ovine viperin inhibits bluetongue virus replication PMCID:    Pubmed No.:32784101 Integrating bioinformatics with pharmacological evaluation for illustrating the action mechanism of herbal formula Jiao'e mixture in suppressing lung carcinoma PMCID:    Pubmed No.:34400263 Inhibitory effect of INT-777 on lipopolysaccharide-induced cognitive impairment, neuroinflammation, apoptosis, and synaptic dysfunction in mice PMCID:    Pubmed No.:30144494 Silymarin ameliorates the disordered glucose metabolism of mice with diet-induced obesity by activating the hepatic SIRT1 pathway PMCID:    Pubmed No.:33901577 Melatonin ameliorates excessive PINK1/Parkin-mediated mitophagy by enhancing SIRT1 expression in granulosa cells of PCOS PMCID:    Pubmed No.:32343612 Atractylenolide III ameliorates cerebral ischemic injury and neuroinflammation associated with inhibiting JAK2/STAT3/Drp1-dependent mitochondrial fission in microglia PMCID:    Pubmed No.:30981186 Eupatilin ameliorates dextran sulphate sodium-induced colitis in mice partly through promoting AMPK activation PMCID:    Pubmed No.:30097122 Decreased immunoglobulin G in brain regions of elder female APOE4-TR mice accompany with Aβ accumulation PMCID:    Pubmed No.:30700991 Radiosensitizing effect of gold nanoparticle loaded with small interfering RNA-SP1 on lung cancer: AuNPs-si-SP1 regulates GZMB for radiosensitivity PMCID:    Pubmed No.:34517158 Resveratrol chemosensitizes adriamycin‐resistant breast cancer cells by modulating miR‐122‐5p PMCID:    Pubmed No.:31155753 The influence of the Chuyou Yuyang granule on the Toll‐like receptor/nuclear factor‐κB signal pathway in Helicobacter pylori‐positive peptic ulcer patients PMCID:    Pubmed No.:31034651 Simultaneous interference of SP1 and HIF1α retarding the proliferation, migration, and invasion of human microvascular endothelial cells (HMEC‐1) under hypoxia PMCID:    Pubmed No.:31135072 Alpha-Mangostin Ameliorates Bleomycin-Induced Pulmonary Fibrosis in Mice Partly Through Activating Adenosine 5′-Monophosphate-Activated Protein Kinase PMCID:    Pubmed No.:31798444 MicroRNA-141-5p Acts as a Tumor Suppressor via Targeting RAB32 in Chronic Myeloid Leukemia PMCID:    Pubmed No.:32038235 Sodium Houttuyfonate Alleviates Post-infarct Remodeling in Rats via AMP-Activated Protein Kinase Pathway PMCID:    Pubmed No.:30319423 Hederagenin Attenuates Cerebral Ischaemia/Reperfusion Injury by Regulating MLK3 Signalling PMCID:    Pubmed No.:32848779 Indoprofen exerts a potent therapeutic effect against sepsis by alleviating high mobility group box 1-mediated inflammatory responses PMCID:    Pubmed No.:34755645 Albumin fusion improves the pharmacokinetics and in vivo antitumor efficacy of canine interferon gamma PMCID:    Pubmed No.:30639219 Artemisinin Derivatives Inhibit Non-small Cell Lung Cancer Cells Through Induction of ROS-dependent Apoptosis/Ferroptosis PMCID:    Pubmed No.:34093811 Probiotics Exert Protective Effect against Sepsis-Induced Cognitive Impairment by Reversing Gut Microbiota Abnormalities PMCID:    Pubmed No.:33284020 Clostridium butyricum Attenuates Chronic Unpredictable Mild Stress-Induced Depressive-Like Behavior in Mice via the Gut-Brain Axis PMCID:    Pubmed No.:30040410 The Neuropeptide Spexin Promotes the Osteoblast Differentiation of MC3T3-E1 Cells via the MEK/ERK Pathway and Bone Regeneration in a Mouse Calvarial Defect Model PMCID:    Pubmed No.:34951679 Protection of the enhanced Nrf2 deacetylation and its downstream transcriptional activity by SIRT1 in myocardial ischemia/reperfusion injury PMCID:    Pubmed No.:34403762 Caveolin-1 knockout mice have altered serum N-glycan profile and sialyltransferase tissue expression PMCID:    Pubmed No.:34462883 Factor Xa inhibitor rivaroxaban suppresses experimental abdominal aortic aneurysm progression via attenuating aortic inflammation PMCID:    Pubmed No.:33227452 NEDD4 Negatively Regulates GITR via Ubiquitination in Immune Microenvironment of Melanoma PMCID:    Pubmed No.:31824170 Lanosterol modulates proteostasis via dissolving cytosolic sequestosomes/aggresome-like induced structures PMCID:    Pubmed No.:31785334 The positive role of vitronectin in radiation induced lung toxicity: the in vitro and in vivo mechanism study PMCID:    Pubmed No.:29661186 Hepatoprotective Effect of Apigenin Against Liver Injury via the Non-canonical NF-κB Pathway In Vivo and In Vitro PMCID:    Pubmed No.:32458347 Protective effects of Genistein on the cognitive deficits induced by chronic sleep deprivation PMCID:    Pubmed No.:32115816 Sarsasapogenin ameliorates diabetes‐associated memory impairment and neuroinflammation through down‐regulation of PAR‐1 receptor PMCID:    Pubmed No.:33885189 Protective effects of sarsasapogenin against early stage of diabetic nephropathy in rats PMCID:    Pubmed No.:29682805 A novel compound AB-38b improves diabetes-associated cognitive decline in mice via activation of Nrf2/ARE pathway PMCID:    Pubmed No.:31132419 Inhibition of Autophagy with Chloroquine Enhanced Sinoporphyrin Sodium Mediated Photodynamic Therapy-induced Apoptosis in Human Colorectal Cancer Cells PMCID:    Pubmed No.:30662343 Interleukin-27 prevents LPS-induced inflammatory osteolysis by inhibiting osteoclast formation and function PMCID:    Pubmed No.:30972153 P27 deletion enhances hematopoiesis by paracrine action of IL22 secreted from bone marrow mesenchymal stem cells PMCID:    Pubmed No.:32269712 Inactivation of TSC1 promotes epithelial-mesenchymal transition of renal tubular epithelial cells in mouse diabetic nephropathy PMCID:    Pubmed No.:31235817 Astragaloside IV ameliorates neuroinflammation-induced depressive-like behaviors in mice via the PPARγ/NF-κB/NLRP3 inflammasome axis PMCID:    Pubmed No.:29795356 Inhibitory effects of isocryptotanshinone on gastric cancer PMCID:    Pubmed No.:29915371 Attenuation of melanogenesis by Nymphaea nouchali (Burm. f) flower extract through the regulation of cAMP/CREB/MAPKs/MITF and proteasomal degradation of tyrosinase PMCID:    Pubmed No.:30224716 Neuroprotective Effects of Rhynchophylline Against Aβ1–42-Induced Oxidative Stress, Neurodegeneration, and Memory Impairment Via Nrf2–ARE Activation PMCID:    Pubmed No.:34170454 DR7 encoded by human herpesvirus 6 promotes glioma development and progression PMCID:    Pubmed No.:30881135 The biphasic effects of the oxLDL/β2GPI/anti-β2GPI complex on VSMC proliferation and apoptosis PMCID:    Pubmed No.:30738928 BMP9 inhibits the proliferation and migration of fibroblast-like synoviocytes in rheumatoid arthritis via the PI3K/AKT signaling pathway PMCID:    Pubmed No.:31203157 MCTR3 reduces LPS-induced acute lung injury in mice via the ALX/PINK1 signaling pathway PMCID:    Pubmed No.:33268042 Saikosaponin-d attenuated lipopolysaccharide-induced depressive-like behaviors via inhibiting microglia activation and neuroinflammation PMCID:    Pubmed No.:31926446 Inhibiting NLRP3 inflammasome with MCC950 ameliorates perioperative neurocognitive disorders, suppressing neuroinflammation in the hippocampus in aged mice PMCID:    Pubmed No.:32087497 Effects of interleukin-6 and IL-6/AMPK signaling pathway on mitochondrial biogenesis and astrocytes viability under experimental septic condition PMCID:    Pubmed No.:29674256 Hyperoside suppresses BMP-7-dependent PI3K/AKT pathway in human hepatocellular carcinoma cells PMCID:    Pubmed No.:34532370 Syngeneic bone marrow transplantation in combination with PI3K inhibitor reversed hyperglycemia in later-stage streptozotocin-induced diabetes PMCID:    Pubmed No.:34988151 Impairment of Intestinal Monocarboxylate Transporter 6 Function and Expression in Diabetic Rats Induced by Combination of High-Fat Diet and Low Dose of Streptozocin: Involvement of Butyrate–Peroxisome Proliferator-Activated Receptor-γ Activation PMCID:    Pubmed No.:30923035 Prediction of Atorvastatin Pharmacokinetics in High-Fat Diet and Low-Dose Streptozotocin-Induced Diabetic Rats Using a Semiphysiologically Based Pharmacokinetic Model Involving Both Enzymes and Transporters PMCID:    Pubmed No.:31399507 The Role of CDR1as in Proliferation and Differentiation of Human Umbilical Cord-Derived Mesenchymal Stem Cells PMCID:    Pubmed No.:31281369 Polydatin protects SH-SY5Y in models of Parkinson's disease by promoting Atg5-mediated but parkin-independent autophagy PMCID:    Pubmed No.:31926197 Curcumin-activated autophagy plays a negative role in its anti-osteoclastogenic effect PMCID:    Pubmed No.:31678610 Protective Effects of 1-Methylnicotinamide on Aβ1–42-Induced Cognitive Deficits, Neuroinflammation and Apoptosis in Mice PMCID:    Pubmed No.:30635816 Paeonol Inhibits Oxidized Low-Density Lipoprotein-Induced Vascular Endothelial Cells Autophagy by Upregulating the Expression of miRNA-30a PMCID:    Pubmed No.:29472864 UPLC/Q-TOFMS-Based Metabolomics Approach to Reveal the Protective Role of Other Herbs in An-Gong-Niu-Huang Wan Against the Hepatorenal Toxicity of Cinnabar and Realgar PMCID:    Pubmed No.:29950994 Novobiocin, a Newly Found TRPV1 Inhibitor, Attenuates the Expression of TRPV1 in Rat Intestine and Intestinal Epithelial Cell Line IEC-6 PMCID:    Pubmed No.:30374305 Identification of extracellular vesicles-transported miRNAs in Erlotinib-resistant head and neck squamous cell carcinoma PMCID:    Pubmed No.:32157550 hucMSCs Attenuate IBD through Releasing miR148b-5p to Inhibit the Expression of 15-lox-1 in Macrophages PMCID:    Pubmed No.:31275059 Both LmCYP4G genes function in decreasing cuticular penetration of insecticides in Locusta migratoria PMCID:    Pubmed No.:32419293 Effect of simvastatin and microRNA-21 inhibitor on metastasis and progression of human salivary adenoid cystic carcinoma PMCID:    Pubmed No.:30021341 CXCR1/CXCR2 antagonist G31P inhibits nephritis in a mouse model of uric acid nephropathy PMCID:    Pubmed No.:30257327 Norfloxacin suppresses Leptospira-induced inflammation through inhibiting p65 and ERK phosphorylation and NLRP3 inflammasome activation PMCID:    Pubmed No.:34826552 Activation of the G Protein-Coupled Estrogen Receptor Elicits Store Calcium Release and Phosphorylation of the Mu-Opioid Receptors in the Human Neuroblastoma SH-SY5Y Cells PMCID:    Pubmed No.:31920512 MiR-146a Ameliorates Hemoglobin-Induced Microglial Inflammatory Response via TLR4/IRAK1/TRAF6 Associated Pathways PMCID:    Pubmed No.:32317924 The novel GLP-1/GIP dual agonist DA3-CH is more effective than liraglutide in reducing endoplasmic reticulum stress in diabetic rats with cerebral ischemia-reperfusion injury PMCID:    Pubmed No.:33500109 Essential oil from Fructus Alpinia zerumbet (fruit of Alpinia zerumbet (Pers.) Burtt.et Smith) protected against aortic endothelial cell injury and inflammation in vitro and in vivo PMCID:    Pubmed No.:30880260 Mechanisms dissection of the combination GRS derived from ShengMai preparations for the treatment of myocardial ischemia/reperfusion injury PMCID:    Pubmed No.:32946961 A balanced game: chicken macrophage response to ALV-J infection PMCID:    Pubmed No.:30841905 Dexmedetomidine Attenuates Neuroinflammatory–Induced Apoptosis after Traumatic Brain Injury via Nrf2 signaling pathway PMCID:    Pubmed No.:31478596 Baicalin Protects Mice Brain From Apoptosis in Traumatic Brain Injury Model Through Activation of Autophagy PMCID:    Pubmed No.:30686973 Carbon ion combined with tigecycline inhibits lung cancer cell proliferation by inducing mitochondrial dysfunction PMCID:    Pubmed No.:33065148 PGRN−/− TAMs-derived exosomes inhibit breast cancer cell invasion and migration and its mechanism exploration PMCID:    Pubmed No.:33181174 Perilla aldehyde attenuates CUMS-induced depressive-like behaviors via regulating TXNIP/TRX/NLRP3 pathway in rats PMCID:    Pubmed No.:29800538 Overexpression of miR-146a Might Regulate Polarization Transitions of BV-2 Cells Induced by High Glucose and Glucose Fluctuations PMCID:    Pubmed No.:31695681 Antitumor activity of Koningic acid in thyroid cancer by inhibiting cellular glycolysis PMCID:    Pubmed No.:34264510 Effects of low-dose ALA-PDT on fibroblast photoaging induced by UVA irradiation and the underlying mechanisms PMCID:    Pubmed No.:31075320 HHQ-4, a quinoline derivate, preferentially inhibits proliferation of glucose-deprived breast cancer cells as a GRP78 down-regulator PMCID:    Pubmed No.:31022492 Fluoride induces apoptosis via inhibiting SIRT1 activity to activate mitochondrial p53 pathway in human neuroblastoma SH-SY5Y cells PMCID:    Pubmed No.:29609003 CTRP9 induces iNOS expression through JAK2/STAT3 pathway in Raw 264.7 and peritoneal macrophages PMCID:    Pubmed No.:31837806 Bmi-1 determines the stemness of renal stem or progenitor cells PMCID:    Pubmed No.:32819581 Shp2 regulates PM2.5-induced airway epithelial barrier dysfunction by modulating ERK1/2 signaling pathway PMCID:    Pubmed No.:34252507 Tert-butylhydroquinone enhanced angiogenesis and astrocyte activation by activating nuclear factor-E2-related factor 2/heme oxygenase-1 after focal cerebral ischemia in mice PMCID:    Pubmed No.:31283926 PID1 in adipocytes modulates whole-body glucose homeostasis PMCID:    Pubmed No.:29391195 Liver proteomics analysis reveals abnormal metabolism of bile acid and arachidonic acid in Chinese hamsters with type 2 diabetes mellitus PMCID:    Pubmed No.:33722748 Involvement of NLRP3 inflammasome in methamphetamine-induced microglial activation through miR-143/PUMA axis PMCID:    Pubmed No.:30394308 Absent in melanoma 2 suppresses epithelial‐mesenchymal transition via Akt and inflammasome pathways in human colorectal cancer cells PMCID:    Pubmed No.:31210372 miR‐125a‐3p suppresses the growth and progression of papillary thyroid carcinoma cell by targeting MMP11 PMCID:    Pubmed No.:31489990 Luteolin attenuates high glucose-induced podocyte injury via suppressing NLRP3 inflammasome pathway PMCID:    Pubmed No.:30935950 Breviscapine provides a neuroprotective effect after traumatic brain injury by modulating the Nrf2 signaling pathway PMCID:    Pubmed No.:31042302 Taurine-Mediated IDOL Contributes to Resolution of Streptococcus uberis Infection | Infection and Immunity PMCID:    Pubmed No.:33593888 Tprn is essential for the integrity of stereociliary rootlet in cochlear hair cells in mice PMCID:    Pubmed No.:30159668 YAP mediates the interaction between the Hippo and PI3K/Akt pathways in mesangial cell proliferation in diabetic nephropathy PMCID:    Pubmed No.:32816106 Adipocytes induce the resistance of ovarian cancer to carboplatin through ANGPTL4 PMCID:    Pubmed No.:32705217 Flavonoids extracted from mulberry (Morus alba L.) leaf improve skeletal muscle mitochondrial function by activating AMPK in type 2 diabetes PMCID:    Pubmed No.:31639486 Autophagy mediated by JNK1 resists apoptosis through TRAF3 degradation in osteoclastogenesis PMCID:    Pubmed No.:31654668 Mitoferrin 2 deficiency prevents mitochondrial iron overload-induced endothelial injury and alleviates atherosclerosis PMCID:    Pubmed No.:33711329 N-acetylcysteine prevents orchiectomy-induced osteoporosis by inhibiting oxidative stress and osteocyte senescence PMCID:    Pubmed No.:31396339 Pyrroloquinoline quinone prevents knee osteoarthritis by inhibiting oxidative stress and chondrocyte senescence PMCID:    Pubmed No.:30972174 Deletion of p16 prevents estrogen deficiency-induced osteoporosis by inhibiting oxidative stress and osteocyte senescence PMCID:    Pubmed No.:32194914 Mitochondrial-targeted antioxidant MitoQ provides neuroprotection and reduces neuronal apoptosis in experimental traumatic brain injury possibly via the Nrf2-ARE pathway PMCID:    Pubmed No.:30018728 Deletion of aquaporin-4 aggravates brain pathology after blocking of the meningeal lymphatic drainage PMCID:    Pubmed No.:30347264 Curcumin provides neuroprotection in model of traumatic brain injury via the Nrf2-ARE signaling pathway PMCID:    Pubmed No.:29626606 Identification and Functional Verification of MicroRNA-16 Family Targeting Intestinal Divalent Metal Transporter 1 (DMT1) in vitro and in vivo PMCID:    Pubmed No.:31316397 Docosahexaenoic acid inhibits hepatic stellate cell activation to attenuate liver fibrosis in a PPARγ-dependent manner PMCID:    Pubmed No.:31437794 1-Methylnicotinamide attenuates lipopolysaccharide-induced cognitive deficits via targeting neuroinflammation and neuronal apoptosis PMCID:    Pubmed No.:31639616 Protective effects of tauroursodeoxycholic acid on lipopolysaccharide-induced cognitive impairment and neurotoxicity in mice PMCID:    Pubmed No.:30986644 Geniposide, a sonic hedgehog signaling inhibitor, inhibits the activation of hepatic stellate cell PMCID:    Pubmed No.:31005778 Effect of silencing HIF-1α gene on testicle spermatogenesis function in varicocele rats PMCID:    Pubmed No.:31377879 Nagilactone D ameliorates experimental pulmonary fibrosis in vitro and in vivo via modulating TGF-β/Smad signaling pathway PMCID:    Pubmed No.:31953203 Chitosan-gold nanoparticles mediated gene delivery of c-myb facilitates osseointegration of dental implants in ovariectomized rat PMCID:    Pubmed No.:30307328 PPAR-γ Promotes Hematoma Clearance through Haptoglobin-Hemoglobin-CD163 in a Rat Model of Intracerebral Hemorrhage PMCID:    Pubmed No.:30123388 Thiamine ameliorates inflammation of the ruminal epithelium of Saanen goats suffering from subacute ruminal acidosis PMCID:    Pubmed No.:31837780 Effect of seasonal variance on intestinal epithelial barriers and the associated innate immune response of the small intestine of the Chinese soft-shelled turtles PMCID:    Pubmed No.:31857223 Echinocystic acid provides a neuroprotective effect via the PI3K/AKT pathway in intracerebral haemorrhage mice PMCID:    Pubmed No.:32055597 The JAK2/STAT3 pathway is involved in dexmedetomidine-induced myocardial protection in rats undergoing cardiopulmonary bypass PMCID:    Pubmed No.:32395527 Phenotypic characterization of a novel type 2 diabetes animal model in a SHANXI MU colony of Chinese hamsters PMCID:    Pubmed No.:31025261 Protective effect of bone marrow mesenchymal stem cell-derived exosomes against the reproductive toxicity of cyclophosphamide is associated with the p38MAPK/ERK and AKT signaling pathways PMCID:    Pubmed No.:33565424 HSC-specific knockdown of GGPPS alleviated CCl4-induced chronic liver fibrosis through mediating RhoA/Rock pathway PMCID:    Pubmed No.:31105844 Synergistic protection of tetramethylpyrazine phosphate and borneol on brain microvascular endothelium cells injured by hypoxia PMCID:    Pubmed No.:31105826 Echinocystic acid, a natural plant extract, alleviates cerebral ischemia/reperfusion injury via inhibiting the JNK signaling pathway PMCID:    Pubmed No.:31425684 6-Gingerol attenuates microglia-mediated neuroinflammation and ischemic brain injuries through Akt-mTOR-STAT3 signaling pathway PMCID:    Pubmed No.:32681941 Bacteroides fragilis alleviates the symptoms of lupus nephritis via regulating CD1d and CD86 expressions in B cells PMCID:    Pubmed No.:32721450 Quercetin reverses chronic unpredictable mild stress-induced depression-like behavior in vivo by involving nuclear factor-E2-related factor 2 PMCID:    Pubmed No.:34529966 Naringenin attenuates endoplasmic reticulum stress, reduces apoptosis, and improves functional recovery in experimental traumatic brain injury PMCID:    Pubmed No.:34324877 Sestrin2 overexpression attenuates focal cerebral ischemic injury in rat by increasing Nrf2/HO-1 pathway-mediated angiogenesis PMCID:    Pubmed No.:31085280 Piperlongumine Inhibits Zika Virus Replication In vitro and Promotes Up-Regulation of HO-1 Expression, Suggesting An Implication of Oxidative Stress PMCID:    Pubmed No.:33185862 Human umbilical cord mesenchymal stem cells alleviate inflammatory bowel disease by inhibiting ERK phosphorylation in neutrophils PMCID:    Pubmed No.:31938969 Ketamine ameliorates oxidative stress-induced apoptosis in experimental traumatic brain injury via the Nrf2 pathway PMCID:    Pubmed No.:29713142 Combined effect of vitamin C and vitamin D 3 on intestinal epithelial barrier by regulating Notch signaling pathway PMCID:    Pubmed No.:33964955 Increase in P-glycoprotein levels in the blood-brain barrier of partial portal vein ligation /chronic hyperammonemia rats is medicated by ammonia/reactive oxygen species/ERK1/2 activation: In vitro and in vivo studies PMCID:    Pubmed No.:30639310 A novel TGF-β receptor II mutation (I227T/N236D) promotes aggressive phenotype of oral squamous cell carcinoma via enhanced EGFR signaling PMCID:    Pubmed No.:33246423 Long Noncoding RNA N-BLR Upregulates the Migration and Invasion of Gastric Adenocarcinoma PMCID:    Pubmed No.:30970439 Atorvastatin ameliorates depressive behaviors and neuroinflammatory in streptozotocin-induced diabetic mice PMCID:    Pubmed No.:31786648 Cholecystokinin-8 attenuates methamphetamine-induced inflammatory activation of microglial cells through CCK2 receptor PMCID:    Pubmed No.:32916201 Ginsenoside Rh2 inhibits HeLa cell energy metabolism and induces apoptosis by upregulating voltage‑dependent anion channel 1 PMCID:    Pubmed No.:33000213 Inhibition of TREM-1 attenuates early brain injury after subarachnoid hemorrhage via downregulation of p38MAPK/MMP-9 and preservation of ZO-1 PMCID:    Pubmed No.:30910643 Osteopontin promotes cancer cell drug resistance, invasion, and lactate production and is associated with poor outcome of patients with advanced non-small-cell lung cancer PMCID:    Pubmed No.:30275702 Rhein attenuates PTZ‑induced epilepsy and exerts neuroprotective activity via inhibition of the TLR4-NFκB signaling pathway PMCID:    Pubmed No.:34090938 The Involvement of Mitochondrial Biogenesis in Selenium Reduced Hyperglycemia-Aggravated Cerebral Ischemia Injury PMCID:    Pubmed No.:32447509 Interleukins 6/8 and cyclooxygenase‐2 release and expressions are regulated by oxidative stress‐JAK2/STAT3 signaling pathway in human bronchial epithelial cells exposed to particulate matter ≤2.5 μm PMCID:    Pubmed No.:32212198 RNPS1 inhibition aggravates ischemic brain injury and promotes neuronal death PMCID:    Pubmed No.:31831174 DKK1 is epigenetically downregulated by promoter methylation and inhibits bile acid-induced gastric intestinal metaplasia PMCID:    Pubmed No.:31952791 FoxO1-mediated autophagy plays an important role in the neuroprotective effects of hydrogen in a rat model of vascular dementia PMCID:    Pubmed No.:29885845 Islet Transplantation Attenuating Testicular Injury in Type 1 Diabetic Rats Is Associated with Suppression of Oxidative Stress and Inflammation via Nrf-2/HO-1 and NF-κB Pathways PMCID:    Pubmed No.:31583254 The Long Noncoding RNA LOXL1-AS1 Promotes the Proliferation, Migration, and Invasion in Hepatocellular Carcinoma PMCID:    Pubmed No.:33381389 Pioglitazone prevents cholesterol gallstone formation through the regulation of cholesterol homeostasis in guinea pigs with a lithogenic diet PMCID:    Pubmed No.:31829191 Electromagnetic Fields Ameliorate Insulin Resistance and Hepatic Steatosis by Modulating Redox Homeostasis and SREBP-1c Expression in db/db Mice PMCID:    Pubmed No.:33727836 Chotosan ameliorates cognitive impairment and hippocampus neuronal loss in experimental vascular dementia via activating the Nrf2-mediated antioxidant pathway PMCID:    Pubmed No.:30642751 Schaftoside ameliorates oxygen glucose deprivation-induced inflammation associated with the TLR4/Myd88/Drp1-related mitochondrial fission in BV2 microglia cells PMCID:    Pubmed No.:30528467 Chlorogenic acid prevents paraquat-induced apoptosis via Sirt1-mediated regulation of redox and mitochondrial function PMCID:    Pubmed No.:31106605 Research on the establishment of chronic stress‐induced premature ovarian failure the rat model and effects of Chinese medicine Muniziqi treatment PMCID:    Pubmed No.:30512210 Magnesium isoglycyrrhizinate suppresses LPS-induced inflammation and oxidative stress through inhibiting NF-κB and MAPK pathways in RAW264.7 cells PMCID:    Pubmed No.:30617018 Thioredoxin-interacting protein mediates mitochondrion-dependent apoptosis in early brain injury after subarachnoid hemorrhage PMCID:    Pubmed No.:29905889 Metabolism of selected model substrates and insecticides by recombinant CYP6FD encoded by its gene predominately expressed in the brain of Locusta migratoria PMCID:    Pubmed No.:31400777 Activation of RAW264.7 macrophage by Exopolysaccharide from Aphanothece halaphytica (EPSAH) and the underlying mechanisms PMCID:    Pubmed No.:32083746 Cytoskeletal alteration modulates cancer cell invasion through RhoA-YAP signaling in stromal fibroblasts PMCID:    Pubmed No.:30921404 Cardiopulmonary Bypass Induces Acute Lung Injury via the High-Mobility Group Box 1/Toll-Like Receptor 4 Pathway PMCID:    Pubmed No.:33062073 Spinal miR-34a regulates inflammatory pain by targeting SIRT1 in complete Freund's adjuvant mice PMCID:    Pubmed No.:31296380 Mussel adhesive protein blended with gelatin loaded into nanotube titanium dental implants enhances osseointegration PMCID:    Pubmed No.:32557198 Contribution of Hepatic Retinaldehyde Dehydrogenase Induction to Impairment of Glucose Metabolism by High‐Fat‐Diet Feeding in C57BL/6J Mice PMCID:    Pubmed No.:29753302 Alterations in the Neurobehavioral Phenotype and ZnT3/CB-D28k Expression in the Cerebral Cortex Following Lithium-Pilocarpine-Induced Status Epilepticus: the Ameliorative Effect of Leptin PMCID:    Pubmed No.:29687372 Upregulated microRNA-423-5p promotes oxidative stress through targeting glutathione S-transferase mu 1 in asthenozoospermia PMCID:    Pubmed No.:33507590 4‐Sulfonyloxy/alkoxy benzoxazolone derivatives with high anti‐inflammatory activities: Synthesis, biological evaluation, and action mechanism via p38/ERK‐NF‐κB/iNOS pathway PMCID:    Pubmed No.:32915501 Gambogenic acid triggers apoptosis in human nasopharyngeal carcinoma CNE-2Z cells by activating volume-sensitive outwardly rectifying chloride channel PMCID:    Pubmed No.:30654125 Activation of the Nrf2/HO-1 signaling pathway contributes to the protective effects of baicalein against oxidative stress-induced DNA damage and apoptosis in HEI193 Schwann cells PMCID:    Pubmed No.:30662338 The protective effect of small peptides from Periplaneta americana on hydrogen peroxide–induced apoptosis of granular cells PMCID:    Pubmed No.:34155600 Design, Synthesis, Molecular Docking, and Biological Evaluation of New Emodin Anthraquinone Derivatives as Potential Antitumor Substances PMCID:    Pubmed No.:32627416 The role of E2F1-topoIIβ signaling in regulation of cell cycle exit and neuronal differentiation of human SH-SY5Y cells PMCID:    Pubmed No.:30216786 Inhibition of N822K T>A mutation-induced constitutive c-KIT activation in AML cells triggers apoptotic and autophagic pathways leading to death PMCID:    Pubmed No.:31217744 Neuroepithelial Cell Transforming Gene 1 Acts as an Oncogene and Is Mediated by miR-22 in Human Non-Small-Cell Lung Cancer PMCID:    Pubmed No.:32420320 PRDX2 Promotes the Proliferation and Metastasis of Non-Small Cell Lung Cancer In Vitro and In Vivo PMCID:    Pubmed No.:32908916 SS31 attenuates oxidative stress and neuronal apoptosis in early brain injury following subarachnoid hemorrhage possibly by the mitochondrial pathway PMCID:    Pubmed No.:31785308 Overexpression of adiponectin alleviates intracerebral hemorrhage-induced brain injury in rats via suppression of oxidative stress PMCID:    Pubmed No.:29870775 Paeoniflorin exerts neuroprotective effects by modulating the M1/M2 subset polarization of microglia/macrophages in the hippocampal CA1 region of vascular dementia rats via cannabinoid receptor 2 PMCID:    Pubmed No.:29560022 MicroRNA-1297 inhibits proliferation and promotes apoptosis in gastric cancer cells by downregulating CDC6 expression PMCID:    Pubmed No.:31419217 Haem relieves hyperoxia-mediated inhibition of HMEC-1 cell proliferation, migration and angiogenesis by inhibiting BACH1 expression PMCID:    Pubmed No.:33632168 Effect of histone demethylase KDM5A on the odontogenic differentiation of human dental pulp cells PMCID:    Pubmed No.:32208897 The novel GLP-1/GIP dual receptor agonist DA3-CH is neuroprotective in the pilocarpine-induced epileptogenesis rat model PMCID:    Pubmed No.:31121474 Post-treatment with the GLP-1 analogue liraglutide alleviate chronic inflammation and mitochondrial stress induced by Status epilepticus PMCID:    Pubmed No.:29549796 The microglial activation profile and associated factors after experimental spinal cord injury in rats PMCID:    Pubmed No.:30275694 Systematic Administration of B Vitamins Alleviates Diabetic Pain and Inhibits Associated Expression of P2X3 and TRPV1 in Dorsal Root Ganglion Neurons and Proinflammatory Cytokines in Spinal Cord in Rats PMCID:    Pubmed No.:32104520 Phosphorylated Hsp27 prevents LPS‐induced excessive inflammation in THP‐1 cells via suppressing ROS‐mediated upregulation of CBP PMCID:    Pubmed No.:31483551 Activation of the Nrf2-ARE signal pathway after blast induced traumatic brain injury in mice PMCID:    Pubmed No.:30648894 CART mitigates oxidative stress and DNA damage in memory deficits of APP/PS1 mice via upregulating β‑amyloid metabolism‑associated enzymes PMCID:    Pubmed No.:33604684 A GLP‑1 receptor agonist attenuates human islet amyloid polypeptide‑induced autophagy and apoptosis in MIN6 cells PMCID:    Pubmed No.:30569165 Angiotensin II upregulates cyclophilin A by enhancing ROS production in rat cardiomyocytes PMCID:    Pubmed No.:30221707 The GLP-1/GIP dual-receptor agonist DA5-CH inhibits the NF-κB inflammatory pathway in the MPTP mouse model of Parkinson's disease more effectively than the GLP-1 single-receptor agonist NLY01 PMCID:    Pubmed No.:34125470 KLF4 upregulation is involved in alternative macrophage activation during secondary Echinococcus granulosus infection PMCID:    Pubmed No.:31407814 Sorafenib blocks the activation of the HIF-2α/VEGFA/EphA2 pathway, and inhibits the rapid growth of residual liver cancer following high-intensity focused ultrasound therapy in vivo PMCID:    Pubmed No.:33640712 Interaction between CA repeat microsatellites and HIF1α regulated the transcriptional activity of porcine IGF1 promoter PMCID:    Pubmed No.:31673965 Bovine bta-microRNA-1271 Promotes Preadipocyte Differentiation by Targeting Activation Transcription Factor 3 PMCID:    Pubmed No.:33040719 Human umbilical cord mesenchymal stem cell exosomes alleviate sepsis-associated acute kidney injury via regulating microRNA-146b expression PMCID:    Pubmed No.:32048128 MicroRNA-136-3p inhibits glioma tumorigenesis in vitro and in vivo by targeting KLF7 PMCID:    Pubmed No.:32677950 Semaglutide-mediated protection against Aβ correlated with enhancement of autophagy and inhibition of apotosis PMCID:    Pubmed No.:33222922 Effect of Oleanolic Acid on Apoptosis and Autophagy of SMMC-7721 Hepatoma Cells PMCID:    Pubmed No.:32424110 Biochanin A Reduces Inflammatory Injury and Neuronal Apoptosis following Subarachnoid Hemorrhage via Suppression of the TLRs/TIRAP/MyD88/NF-κB Pathway PMCID:    Pubmed No.:29971136 Increased lactic acid content associated with extracellular matrix depletion in a porcine disc degeneration induced by superficial annular lesion PMCID:    Pubmed No.:31747924 Effects of erythropoietin for precaution of steroid-induced femoral head necrosis in rats PMCID:    Pubmed No.:30086737 Effects of claudin‑1 downregulation on the physiological processes of gallbladder cancer SGC996 cells PMCID:    Pubmed No.:30675228 Adiponectin reduces brain injury after intracerebral hemorrhage by reducing NLRP3 inflammasome expression PMCID:    Pubmed No.:31607194 Deferoxamine reduces amyloid-beta peptides genesis and alleviates neural apoptosis after traumatic brain injury PMCID:    Pubmed No.:33788818 Qingxin Kaiqiao Recipe Improves Cognitive Performance, Inhibits Apoptosis, and Reduces Pathological Deposits in APP/PS1 Double Transgenic Mice via the PI3K/Akt Pathway PMCID:    Pubmed No.:32419798 Oxidative stress and mitochondrial dysfunction of retinal ganglion cells injury exposures in long-term blue light PMCID:    Pubmed No.:33344182 Bupleurum polysaccharides ameliorated renal injury in diabetic mice associated with suppression of HMGB1-TLR4 signaling PMCID:    Pubmed No.:31526499 Allicin attenuates early brain injury after experimental subarachnoid hemorrhage in rats PMCID:    Pubmed No.:30773476 Allicin attenuates early brain injury after experimental subarachnoid hemorrhage in rats PMCID:    Pubmed No.:30773476 Trichinella spiralis muscle larvae excretory/secretory products trigger apoptosis and S-phase arrest of the non-small-cell lung cancer line A549 PMCID:    Pubmed No.:32861680 Tetrahydrocurcumin Provides Neuroprotection in Experimental Traumatic Brain Injury and the Nrf2 Signaling Pathway as a Potential Mechanism PMCID:    Pubmed No.:29669346 miR-140 inhibits porcine fetal fibroblasts proliferation by directly targeting type 1 insulin-like growth factor receptor and indirectly inhibiting type 1 insulin-like growth factor receptor expression via SRY-box 4 PMCID:    Pubmed No.:32054205 Aurora A inhibition disrupts chromosome condensation and spindle assembly during the first embryonic division in pigs PMCID:    Pubmed No.:32053743 Mechanism underlying the effect of SO2-induced oxidation on human skin keratinocytes PMCID:    Pubmed No.:33235076 Mechanism of H2S‑mediated ROCK inhibition of total flavones of Rhododendra against myocardial ischemia injury PMCID:    Pubmed No.:31611932 Triptolide protects against TGF‑β1‑induced pulmonary fibrosis by regulating FAK/calpain signaling PMCID:    Pubmed No.:31777561 Mogrol attenuates lipopolysaccharide (LPS)-induced memory impairment and neuroinflammatory responses in mice PMCID:    Pubmed No.:31347387 Cytotoxic effect of interleukin-8 in retinal ganglion cells and its possible mechanisms PMCID:    Pubmed No.:30140629 Administration of Donor-Derived Nonexpanded Adipose Stromal Vascular Fraction Attenuates Ischemia-Reperfusion Injury in Donation After Cardiac Death Rat Renal Transplantation PMCID:    Pubmed No.:34266654 Preliminary Study of Bone Marrow-Derived Mesenchymal Stem Cells Pretreatment With Erythropoietin in Preventing Acute Rejection After Rat Renal Transplantation PMCID:    Pubmed No.:30577280 Mild Hypothermia Protects Renal Function in Ischemia-reperfusion Kidney: An Experimental Study in Mice PMCID:    Pubmed No.:30577273 TPEN Attenuates Neural Autophagy Induced by Synaptically-released Zinc Translocation and Improves Histological Outcomes after Traumatic Brain Injury in Rats PMCID:    Pubmed No.:30143485 Hyperoside alleviated N-acetyl-para-amino-phenol-induced acute hepatic injury via Nrf2 activation PMCID:    Pubmed No.:31933721 Discovery and characterization of a novel splice variant of the p53 tumor suppressor gene in a human T cell leukemia cellline PMCID:    Pubmed No.:32509087 Aspirin-triggered lipoxin A4 attenuates lipopolysaccharide-induced acute lung injury by inhibiting activation of mitogen-activated protein kinases and NF-κB in mice PMCID:    Pubmed No.:31938370 Ethanol Extract of Hizikia fusiforme Induces Apoptosis in B16F10 Mouse Melanoma Cells through ROS-Dependent Inhibition of the PI3K/Akt Signaling Pathway PMCID:    Pubmed No.:32458633 Crucial Roles of 5-HT and 5-HT2 Receptor in Diabetes-Related Lipid Accumulation and Pro-Inflammatory Cytokine Generation in Hepatocytes PMCID:    Pubmed No.:30121645 The Protective Effect of Antioxidants in Areca Nut Extract-Induced Oral Carcinogenesis PMCID:    Pubmed No.:32856877 Nitazoxanide and related thiazolides induce cell death in cancer cells by targeting the 20S proteasome with novel binding modes PMCID:    Pubmed No.:35032461 Pan-cancer analysis, cell and animal experiments revealing TEAD4 as a tumor promoter in ccRCC PMCID:    Pubmed No.:35065165 Leaf extract of Osbeckia octandra induces apoptosis in oral squamous cell carcinoma cells PMCID:    Pubmed No.:35078428 Pyrrolidine Dithiocarbamate Might Mitigate Radiation-Induced Heart Damage at an Early Stage in Rats. PMCID:    Pubmed No.:35392554 Strongylocentrotus nudus Eggs Polysaccharide Enhances Macrophage Phagocytosis Against E.coli Infection by TLR4/STAT3 Axis. PMCID:    Pubmed No.:35370674 Norisoboldine induces the development of Treg cells by promoting fatty acid oxidation-mediated H3K27 acetylation of Foxp3 PMCID:    Pubmed No.:35233835 Empagliflozin Inhibits Hepatic Gluconeogenesis and Increases Glycogen Synthesis by AMPK/CREB/GSK3β Signalling Pathway PMCID:    Pubmed No.:35299662 Protective effects of heterophyllin B against bleomycin-induced pulmonary fibrosis in mice via AMPK activation PMCID:    Pubmed No.:35283110 MCFA alleviate H2O2-induced oxidative stress in AML12 cells via the ERK1/2/Nrf2 pathway PMCID:    Pubmed No.:35262212 Activation of TGR5 Ameliorates Streptozotocin-Induced Cognitive Impairment by Modulating Apoptosis, Neurogenesis, and Neuronal Firing PMCID:    Pubmed No.:35464765 The activation of PPARγ enhances Treg responses through up-regulating CD36/CPT1-mediated fatty acid oxidation and subsequent N-glycan branching of TβRII/IL-2Rα PMCID:    Pubmed No.:35392915 The activation of PPARγ enhances Treg responses through up-regulating CD36/CPT1-mediated fatty acid oxidation and subsequent N-glycan branching of TβRII/IL-2Rα PMCID:    Pubmed No.:35392915 The effect of D-chiro-inositol on renal protection in diabetic mice PMCID:    Pubmed No.:35439732 Effects of Changes in Osmolarity on the Biological Activity of Human Normal Nucleus Pulposus Mesenchymal Stem Cells PMCID:    Pubmed No.:35502327 PGC1α-mediated fatty acid oxidation promotes TGFβ1-induced epithelial-mesenchymal transition and metastasis of nasopharyngeal carcinoma PMCID:    Pubmed No.:35452637 Eplerenone inhibits UUO-induced lymphangiogenesis and cardiac fibrosis by attenuating inflammatory injury PMCID:    Pubmed No.:35428023 H2S Protects Against Immobilization-Induced Muscle Atrophy via Reducing Oxidative Stress and Inflammation PMCID:    Pubmed No.:35464091 Metformin protects 5-Fu-induced chemotherapy oral mucositis by reducing endoplasmic reticulum stress in mice PMCID:    Pubmed No.:35405270 sTREM-1 promotes the phagocytic function of microglia to induce hippocampus damage via the PI3K–AKT signaling pathway PMCID:    Pubmed No.:35487953 Sirtuin 1 alleviates microglia-induced inflammation by modulating the PGC-1α/Nrf2 pathway after traumatic brain injury in male rats PMCID:    Pubmed No.:35487384 A study of diabetes-induced erectile dysfunction treated with human umbilical cord mesenchymal stem cells PMCID:    Pubmed No.:35415927 Fibroblast growth factor 11 inhibits foot-and-mouth disease virus gene expression and replication in vitro PMCID:    Pubmed No.:35387954 Extracellular vesicles derived from astrocyte-treated with haFGF14-154 attenuate Alzheimer phenotype in AD mice PMCID:    Pubmed No.:35664060 Brain-targeted heptapeptide-loaded exosomes attenuated ischemia–reperfusion injury by promoting the transfer of healthy mitochondria from astrocytes to neurons PMCID:    Pubmed No.:35606779 Sublytic C5b-9 Induces CCL3/4 Production and Macrophage Accumulation in Thy-1N Rats via PKC-α/p65/IRF-8 Axis PMCID:    Pubmed No.:35637950 Neonatal inflammation via persistent TGF-β1 downregulation decreases GABAAR expression in basolateral amygdala leading to the imbalance of the local excitation-inhibition circuits and anxiety-like phenotype in adult mice PMCID:    Pubmed No.:35513229 An Emerging Role of Proanthocyanidins on Psoriasis: Evidence from a Psoriasis-Like Mouse Model PMCID:    Pubmed No.:35720176 The secretion of sIgA and dendritic cells activation in the intestinal of cyclophosphamide-induced immunosuppressed mice are regulated by Alhagi honey polysaccharides PMCID:    Pubmed No.:35675749 BCR/ABL1ΔE7-8-9 isoform contributes to tyrosine kinase inhibitor resistance in chronic myeloid leukemia PMCID:    Pubmed No.:35686657 UVB-induced SFRP1 methylation potentiates skin damage by promoting cell apoptosis and DNA damage PMCID:    Pubmed No.:35657114 Effect of miR-101 on the Proliferation and Apoptosis of Goat Hair Follicle Stem Cells PMCID:    Pubmed No.:35741797 Chitosan Oligosaccharide Inhibits the Synthesis of Milk Fat in Bovine Mammary Epithelial Cells through AMPK-Mediated Downstream Signaling Pathway PMCID:    Pubmed No.:35804595 High levels of TDO2 in relation to pro-inflammatory cytokines in synovium and synovial fluid of patients with osteoarthritis PMCID:    Pubmed No.:35733134 Sirt1 overexpression improves senescence-associated pulmonary fibrosis induced by vitamin D deficiency through downregulating IL-11 transcription PMCID:    Pubmed No.:35906886 Oncogenic TRIB2 interacts with and regulates PKM2 to promote aerobic glycolysis and lung cancer cell procession PMCID:    Pubmed No.:35790734 LncRNA-84277 is involved in chronic pain-related depressive behaviors through miR-128-3p/SIRT1 axis in central amygdala PMCID:    Pubmed No.:35959106 Enterobacterial LPS-inducible LINC00152 is regulated by histone lactylation and promotes cancer cells invasion and migration PMCID:    Pubmed No.:35959377 MBD1/HDAC3-miR-5701-FGFR2 axis promotes the development of gastric cancer PMCID:    Pubmed No.:35876658 Effect of Probiotic Fungi against Cognitive Impairment in Mice via Regulation of the Fungal Microbiota–Gut–Brain Axis PMCID:    Pubmed No.:35833673 lncKRT16P6 promotes tongue squamous cell carcinoma progression by sponging miR‑3180 and regulating GATAD2A expression PMCID:    Pubmed No.:35904180 miR-301a-3p promotes hepatic stellate cells activation and liver fibrogenesis via regulating PTEN/PDGFR-β PMCID:    Pubmed No.:35834952 Semaglutide Protects against 6-OHDA Toxicity by Enhancing Autophagy and Inhibiting Oxidative Stress PMCID:    Pubmed No.:35873704 Differential proteome response to H5N1 highly pathogenic avian influenza (HPAI) viruses infection in duck. PMCID:    Pubmed No.:36059479 PPAR-γ alleviates the inflammatory response in TNF-α-induced fibroblast-like synoviocytes by binding to p53 in rheumatoid arthritis PMCID:    Pubmed No.:35918412 Construction of Fzd6Q152E mice through CRISPR/Cas9 technology and their reproduction and identification PMCID:    Pubmed No.:35980530 miR-150 promotes progressive T cell differentiation via inhibiting FOXP1 and RC3H1 PMCID:    Pubmed No.:35999072 Effects of neuron autophagy induced by arsenic and fluoride on spatial learning and memory in offspring rats PMCID:    Pubmed No.:36087721 The protective effect of proanthocyanidins on the psoriasis-like cell models via PI3K/AKT and HO-1 PMCID:    Pubmed No.:36178125 Exploring the synergic mechanism of Ligusticum striatum DC. and borneol in attenuating BMECs injury and maintaining tight junctions against cerebral ischaemia based on the HIF-1α/VEGF signalling pathway PMCID:    Pubmed No.:36183951 Ginseng polysaccharide attenuates red blood cells oxidative stress injury by regulating red blood cells glycolysis and liver gluconeogenesis PMCID:    Pubmed No.:36122792 Oridonin ameliorates caspase-9-mediated brain neuronal apoptosis in mouse with ischemic stroke by inhibiting RIPK3-mediated mitophagy PMCID:    Pubmed No.:36216897 β-catenin ISGylation promotes lipid deposition and apoptosis in ethanol-stimulated liver injury models PMCID:    Pubmed No.:36259544 Cattle Encephalon Glycoside and Ignotin Attenuates Aβ1-42-Mediated Neurotoxicity by Preventing NLRP3 Inflammasome Activation and Modulating Microglial Polarization via TLR4/NF-κB Signaling Pathway PMCID:    Pubmed No.:36214996 Aerobic Glycolysis Induced by mTOR/HIF-1α Promotes Early Brain Injury After Subarachnoid Hemorrhage via Activating M1 Microglia PMCID:    Pubmed No.:36385451 Phosphorylation of Enteroviral 2Apro at Ser/Thr125 Benefits Its Proteolytic Activity and Viral Pathogenesis PMCID:    Pubmed No.:36511115 Maternal circadian disruption before pregnancy impairs the ovarian function of female offspring in mice PMCID:    Pubmed No.:36572306 P38γ modulates the lipid metabolism in non-alcoholic fatty liver disease by regulating the JAK–STAT signaling pathway PMCID:    Pubmed No.:36527390 Halofuginone ameliorates systemic lupus erythematosus by targeting Blk in myeloid-derived suppressor cells PMCID:    Pubmed No.:36493694 SS31 Confers Cerebral Protection by Reversing Mitochondrial Dysfunction in Early Brain Injury Following Subarachnoid Hemorrhage, via the Nrf2- and PGC-1α-Dependent Pathways PMCID:    Pubmed No.:36574150 Mycobacterium tuberculosis PE_PGRS1 promotes mycobacteria intracellular survival via reducing the concentration of intracellular free Ca2+ and suppressing endoplasmic reticulum stress PMCID:    Pubmed No.:36584479 The functional link between TCTP and Drsl1 in deltamethrin-stressed Drosophila Kc cells PMCID:    Pubmed No.:36464172 Neuroprotective effect of hyperoside in MPP+/MPTP -induced dopaminergic neurodegeneration PMCID:    Pubmed No.:36576692 Small Molecule Compound K-7174 Attenuates Neuropsychiatric Manifestations in Lupus-prone Mice PMCID:    Pubmed No.:36521514 Multi-omics analysis unravels positive effect of rotenone on the cordycepin biosynthesis in submerged fermentation of Cordyceps militaris PMCID:    Pubmed No.:36746212 Baicalin Nanocomplexes with an In Situ-Forming Biomimetic Gel Implant for Repair of Calvarial Bone Defects via Localized Sclerostin Inhibition PMCID:    Pubmed No.:36753285 A novel sorbicillinoid compound as a potent anti-inflammation agent through inducing NLRP3 protein degradation PMCID:    Pubmed No.:36788033 Repurposing Axl Kinase Inhibitors for the Treatment of Respiratory Syncytial Virus Infection PMCID:    Pubmed No.:36853000 Cytoplasmic localization of IRF5 induces Wnt5a/E-cadherin degradation and promotes gastric cancer cells metastasis PMCID:    Pubmed No.:36782048 MiR-146a-5p Contributes to Microglial Polarization Transitions Associated With AGEs PMCID:    Pubmed No.:36780120 DIFFERENTIATED EMBRYONIC CHONDROCYTE EXPRESSED GENE-1 IS A CENTRAL SIGNALING COMPONENT IN THE DEVELOPMENT OF COLLAGEN-INDUCED RHEUMATOID ARTHRITIS PMCID:    Pubmed No.:36739947 Shikonin improves pulmonary vascular remodeling in monocrotaline‑induced pulmonary arterial hypertension via regulation of PKM2 PMCID:    Pubmed No.:36734266 Promotion of ferroptosis in head and neck cancer with divalent metal transporter 1 inhibition or salinomycin PMCID:    Pubmed No.:36890422 Silencing MARCH2 Inhibits the Invasion, Migration, and EMT Transformation of Human Colorectal Cancer SW480 Cells PMCID:    Pubmed No.:36959742 Microglial CD11b Knockout Contributes to Axonal Debris Clearance and Axonal Degradation Attenuation via IGF-1 After Acute Optic Nerve Injury PMCID:    Pubmed No.:37145604 Interleukin-37 inhibits desmoglein-3 endocytosis and keratinocyte dissociation via upregulation of Caveolin-1 and inhibition of the STAT3 pathway PMCID:    Pubmed No.:37262304 Silencing of circCacna1c Inhibits ISO-Induced Cardiac Hypertrophy through miR-29b-2-5p/NFATc1 Axis PMCID:    Pubmed No.:37371137 Wwl70-induced ABHD6 inhibition attenuates memory deficits and pathological phenotypes in APPswe/PS1dE9 mice PMCID:    Pubmed No.:37480972 Decidual macrophages derived NO downregulates PD-L1 in trophoblasts leading to decreased Treg cells in recurrent miscarriage PMCID:    Pubmed No.:37520550 17-DMAG ameliorates neuroinflammation and BBB disruption via SOX5 mediated PI3K/Akt pathway after intracerebral hemorrhage in rats PMCID:    Pubmed No.:37517381 A newly-synthesized compound CP-07 alleviates microglia-mediated neuroinflammation and ischemic brain injury via inhibiting STAT3 phosphorylation PMCID:    Pubmed No.:37408577 Estrogen increases the expression of BKCa and impairs the contraction of colon smooth muscle via upregulation of sphingosine kinase 1 PMCID:    Pubmed No.:37642352 Hydrogen Sulfide Prevents LPS-Induced Depression-like Behavior through the Suppression of NLRP3 Inflammasome and Pyroptosis and the Improvement of Mitochondrial Function in the Hippocampus of Mice PMCID:    Pubmed No.:37626978 0.01% Hypochlorous Acid Treats Aspergillus fumigatus Keratitis in Rats by Reducing Fungal Load and Inhibiting the Inflammatory Response PMCID:    Pubmed No.:37531113 C3N nanodots inhibits Aβ peptides aggregation pathogenic path in Alzheimer’s disease PMCID:    Pubmed No.:37714837 Exo-miR-1290-induced by COX-2 overexpression promotes cancer-associated fibroblasts activation and tumor progression by CUL3-Nrf2 pathway in lung adenocarcinoma PMCID:    Pubmed No.:37723559 Targeting SDCBP2 in acute myeloid leukemia PMCID:    Pubmed No.:37714445 GSDME in Endothelial Cells: Inducing Vascular Inflammation and Atherosclerosis via Mitochondrial Damage and STING Pathway Activation PMCID:    Pubmed No.:37761020 Resveratrol ameliorates diabetic encephalopathy through PDE4D/PKA/Drp1 signaling PMCID:    Pubmed No.:37722608 Hippocampus protection from apoptosis by Baicalin in a LiCl-pilocarpine-induced rat status epilepticus model through autophagy activation PMCID:    Pubmed No.:37771639 miR-199a and miR-199b facilitate diffuse gastric cancer progression by targeting Frizzled-6 PMCID:    Pubmed No.:37838767 Brassica oleracea L. extract ameliorates isoproterenol-induced myocardial injury by regulating HIF-1α-mediated glycolysis PMCID:    Pubmed No.:37907131
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.

Price/Size :

USD 368/1mg/vial



Tips: 

For phospho antibody, we provide phospho peptide(0.5mg) and non-phospho peptide(0.5mg).

Describe :

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.

Formula:

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.

Storage:

The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C. 


Note :

This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.
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