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β-Actin (I102) polyclonal antibody AP0060
  • Western blot (WB) analysis of β-Actin (I102) pAb at 1:5000/1:10000/1:20000 dilution Lane1:CT-26 whole cell lysate(40ug) Lane2
Product Nameβ-Actin (I102) polyclonal antibody
Catalog No.AP0060
Swiss-ProtN/A
Host Rabbit
ReactivityHuman,Mouse,Rat,zebrafish,Odontobutis obscurus
ApplicationsWB IP IF
Application_allWB:1:5000~1:20000 IP: 1:100~500 IF: 1:500~1000
BiowMW~ 42 kDa
Alternative NameActin, cytoplasmic 1; Beta-actin; Actin, cytoplasmic 1, N-terminally processed; ACTB; Actin-β; Beta actin;
Purification&PurityThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
ConjugateUnconjugated
ModificationUnmodified
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Product Name :
β-Actin (I102) polyclonal antibody
Background :
All eukaryotic cells express actin, which often constitutes asmuch as 50% of total cellular protein. Actin filaments can form both stable and labile structures and are crucial components of microvilli and the contractile apparatus of muscle cells. While lower eukaryotes, such as yeast, have only one actin gene, higher eukaryotes have several isoforms encoded by a family of genes. At least six types of actin are present in mammalian tissues and fall into three classes. -actin expression is limited to various types of muscle, whereas – and -actin are the principle constituents of filaments in other tissues.Members of the small GTPase family regulate the organization of the actin cytoskeleton. Rho controls the assembly of ctin stress fibers and focal adhesion, Rac regulates ctin filament accumulation at the plasma membrane and Cdc42 stimulates formation of filopodia.
Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :
β-actin (I102) polyclonal antibody detects endogenous levels of β-actin protein.
Immunogen :
Recombinant full length Human β-Actin.
Conjugate :
Unconjugated
Modification :
Unmodified
  • Western blot (WB) analysis of β-Actin (I102) pAb at 1:5000/1:10000/1:20000 dilution Lane1:CT-26 whole cell lysate(40ug) Lane2
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PMCID:    Pubmed No.:24565841 Hemokinin-1 (4-11)-Induced Analgesia Selectively Up-Regulates δ-Opioid Receptor Expression in Mice PMCID:    Pubmed No.:24587368 Luteoloside Suppresses Proliferation and Metastasis of Hepatocellular Carcinoma Cells by Inhibition of NLRP3 Inflammasome PMCID:    Pubmed No.:24587153 Luteolin provides neuroprotection in the models of traumatic brain injury via Nrf2-ARE pathway PMCID:    Pubmed No.:24642087 Granulocyte/Macrophage Colony-Stimulating Factor Influences Angiogenesis by Regulating the Coordinated Expression of VEGF and the Ang/Tie System PMCID:    Pubmed No.:24658178 Wogonin-enhanced reactive oxygen species-induced apoptosis and potentiated cytotoxic effects of chemotherapeutic agents by suppression Nrf2-mediated signaling in HepG2 cells. PMCID:    Pubmed No.:24666416 Phosphorylation of heat shock protein 27 antagonizes TNF-α induced HeLa cell apoptosis via regulating TAK1 ubiquitination and activation of p38 and ERK signaling. PMCID:    Pubmed No.:24686082 Hydroxy-safflor yellow A attenuates Aβ1-42-induced inflammation by modulating the JAK2/STAT3/NF-κB pathway. PMCID:    Pubmed No.:24690200 Induction of ROS-Dependent Mitochondria-Mediated Intrinsic Apoptosis in MDA-MB-231 Cells by Glycoprotein from Codium decorticatum PMCID:    Pubmed No.:24694116 mTOR-targeted therapy: differential perturbation to mitochondrial membrane potential and permeability transition pore plays a role in therapeutic response PMCID:    Pubmed No.:24704448 The mechanisms of 5-FU-PLA-O-CMC-NPS-mediated inhibition of the proliferation of colorectal cancer cell line SW480 PMCID:    Pubmed No.:24740560 Quercetin inhibits the mTORC1/p70S6K signaling-mediated renal tubular epithelial–mesenchymal transition and renal fibrosis in diabetic nephropathy PMCID:    Pubmed No.:26151815 Quercetin inhibits the mTORC1/p70S6K signaling-mediated renal tubular epithelial–mesenchymal transition and renal fibrosis in diabetic nephropathy PMCID:    Pubmed No.:26151815 Mogroside IIIE Attenuates LPS-Induced Acute Lung Injury in Mice Partly Through Regulation of the TLR4/MAPK/NF-κB Axis via AMPK Activation PMCID:    Pubmed No.:28512854 Nuclear Factor E2-Related Factor-2 Negatively Regulates NLRP3 Inflammasome Activity by Inhibiting Reactive Oxygen Species-Induced NLRP3 Priming PMCID:    Pubmed No.:27308893 Decreased progranulin levels in patients and rats with subarachnoid hemorrhage: a potential role in inhibiting inflammation by suppressing neutrophil recruitment PMCID:    Pubmed No.:26527034 Angiotensin(1–7) attenuated Angiotensin II-induced hepatocyte EMT by inhibiting NOX-derived H2O2-activated NLRP3 inflammasome/IL-1β/Smad circuit PMCID:    Pubmed No.:27445100 Lipoxin A4 attenuates LPS-induced mouse acute lung injury via Nrf2-mediated E-cadherin expression in airway epithelial cells PMCID:    Pubmed No.:26845617 Hyaluronan synthase 2 expressed by cancer-associated fibroblasts promotes oral cancer invasion PMCID:    Pubmed No.:27884164 Advanced Glycation Endproducts Impair Endothelial Progenitor Cell Migration and Homing via Syndecan 4 Shedding PMCID:    Pubmed No.:27662820 Resveratrol ameliorates hyperglycemia-induced renal tubular oxidative stress damage via modulating the SIRT1/FOXO3a pathway PMCID:    Pubmed No.:28258028 Cyclin-Dependent Kinase Inhibitor 3 Promotes Cancer Cell Proliferation and Tumorigenesis in Nasopharyngeal Carcinoma by Targeting p27 PMCID:    Pubmed No.:28109073 Folate-targeted nanoparticle delivery of androgen receptor shRNA enhances the sensitivity of hormone-independent prostate cancer to radiotherapy PMCID:    Pubmed No.:28185938 Early Minocycline and Late FK506 Treatment Improves Survival and Alleviates Neuroinflammation, Neurodegeneration, and Behavioral Deficits in Prion-Infected Hamsters PMCID:    Pubmed No.:28083805 Mineral trioxide aggregate enhances the osteogenic capacity of periodontal ligament stem cells via NF‐κB and MAPK signaling pathways PMCID:    Pubmed No.:28749049 Dexamethasone Downregulates SLC7A5 Expression and Promotes Cell Cycle Arrest, Autophagy and Apoptosis in BeWo Cells PMCID:    Pubmed No.:26094588 Silencing HOXD10 by promoter region hypermethylation activates ERK signaling in hepatocellular carcinoma PMCID:    Pubmed No.:29075359 S-adenosylmethionine reduces airway inflammation and fibrosis in a murine model of chronic severe asthma via suppression of oxidative stress PMCID:    Pubmed No.:27256110 d‐Chiro inositol ameliorates endothelial dysfunction via inhibition of oxidative stress and mitochondrial fission PMCID:    Pubmed No.:28087886 eEF2K promotes progression and radioresistance of esophageal squamous cell carcinoma PMCID:    Pubmed No.:28431753 Fms related tyrosine kinase 1 (Flt1) functions as an oncogene and regulates glioblastoma cell metastasis by regulating sonic hedgehog signaling PMCID:    Pubmed No.:28560064 Effect of HM910, a novel camptothecin derivative, on the inhibition of multiple myeloma cell growth in vitro and in vivo PMCID:    Pubmed No.:26045982 Unconjugated bilirubin elevation impairs the function and expression of breast cancer resistance protein (BCRP) at the blood-brain barrier in bile duct-ligated rats PMCID:    Pubmed No.:27180978 The edaravone and 3- n -butylphthalide ring-opening derivative 10b effectively attenuates cerebral ischemia injury in rats PMCID:    Pubmed No.:26073328 Deletion of Nrf2 Exacerbates Oxidative Stress After Traumatic Brain Injury in Mice PMCID:    Pubmed No.:25732597 Combined Erlotinib and PF‐03084014 treatment contributes to synthetic lethality in head and neck squamous cell carcinoma PMCID:    Pubmed No.:29232766 Protective effects of linalool against amyloid beta-induced cognitive deficits and damages in mice PMCID:    Pubmed No.:28235543 Toxic effects of 56Fe ion radiation on the zebrafish (Danio rerio) embryonic development PMCID:    Pubmed No.:28267650 LFG-500, a newly synthesized flavonoid, attenuates lipopolysaccharide-induced acute lung injury and inflammation in mice PMCID:    Pubmed No.:27206337 Neotuberostemonine attenuates bleomycin-induced pulmonary fibrosis by suppressing the recruitment and activation of macrophages PMCID:    Pubmed No.:27144994 Clusterin Modulates Allergic Airway Inflammation by Attenuating CCL20-Mediated Dendritic Cell Recruitment PMCID:    Pubmed No.:26826245 YiQiFuMai Powder Injection Protects against Ischemic Stroke via Inhibiting Neuronal Apoptosis and PKCδ/Drp1-Mediated Excessive Mitochondrial Fission PMCID:    Pubmed No.:29435096 MAGEA10 gene expression in non-small cell lung cancer and A549 cells, and the affinity of epitopes with the complex of HLA-A∗0201 alleles PMCID:    Pubmed No.:26058806 Discovery of a head-to-tail cyclic peptide as the Keap1-Nrf2 protein-protein interaction inhibitor with high cell potency PMCID:    Pubmed No.:29117896 Enhancing the anti-multiple myeloma efficiency in a cancer stem cell xenograft model by conjugating the ABCG2 antibody with microbubbles for a targeted delivery of ultrasound mediated epirubicin PMCID:    Pubmed No.:28232025 Dimethyl fumarate ameliorates dextran sulfate sodium-induced murine experimental colitis by activating Nrf2 and suppressing NLRP3 inflammasome activation PMCID:    Pubmed No.:27184504 3-(2-Oxo-2-phenylethylidene)-2,3,6,7-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4(11bH)-one (compound 1), a novel potent Nrf2/ARE inducer, protects against DSS-induced colitis via inhibiting NLRP3 inflammasome PMCID:    Pubmed No.:26588861 Involvement of pregnane X receptor in the impaired glucose utilization induced by atorvastatin in hepatocytes PMCID:    Pubmed No.:26616219 rLj-RGD3 induces apoptosis via the mitochondrial-dependent pathway and inhibits adhesion, migration and invasion of human HeyA8 cells via FAK pathway PMCID:    Pubmed No.:28038913 Transforming growth factor‐β1 stimulates hedgehog signaling to promote epithelial–mesenchymal transition after kidney injury PMCID:    Pubmed No.:27579669 Doxycycline Attenuates Leptospira-Induced IL-1β by Suppressing NLRP3 Inflammasome Priming PMCID:    Pubmed No.:28791016 Hepatorenal protective effects of medicinal herbs in An-Gong-Niu-Huang Wan (AGNH) against cinnabar- and realgar-induced oxidative stress and inflammatory damage in mice PMCID:    Pubmed No.:29203196 AEG‐1 induces gastric cancer metastasis by upregulation of eIF4E expression PMCID:    Pubmed No.:28661037 Maternal betaine supplementation in rats induces intergenerational changes in hepatic IGF‐1 expression and DNA methylation PMCID:    Pubmed No.:28239993 17beta-estradiol promotes the odonto/osteogenic differentiation of stem cells from apical papilla via mitogen-activated protein kinase pathway PMCID:    Pubmed No.:25403930 Alteration of Cholinergic Anti‐Inflammatory Pathway in Rat With Ischemic Cardiomyopathy–Modified Electrophysiological Function of Heart PMCID:    Pubmed No.:28928157 UCH-L1 Inhibition Suppresses tau Aggresome Formation during Proteasomal Impairment PMCID:    Pubmed No.:28540657 The Pivotal Role of Ca2+ Homeostasis in PBDE-47-Induced Neuronal Apoptosis PMCID:    Pubmed No.:26676572 Mangiferin ameliorates fatty liver via modulation of autophagy and inflammation in high-fat-diet induced mice PMCID:    Pubmed No.:29024899 Melatonin‐induced increase of lipid droplets accumulation and in vitro maturation in porcine oocytes is mediated by mitochondrial quiescence PMCID:    Pubmed No.:28240360 Mangiferin Upregulates Glyoxalase 1 Through Activation of Nrf2/ARE Signaling in Central Neurons Cultured with High Glucose PMCID:    Pubmed No.:27318675 Activation of mTOR signaling mediates the increased expression of AChE in high glucose condition: in vitro and in vivo evidences PMCID:    Pubmed No.:26374551 Hypothalamic POMC expression is required for peripheral insulin action on hepatic gluconeogenesis through regulating STAT3 in sepsis rats PMCID:    Pubmed No.:29285858 Neuroprotection by quercetin via mitochondrial function adaptation in traumatic brain injury: PGC‐1α pathway as a potential mechanism PMCID:    Pubmed No.:29205806 Foxc2 enhances proliferation and inhibits apoptosis through activating Akt/mTORC1 signaling pathway in mouse preadipocytes PMCID:    Pubmed No.:26113535 UCH-L1 Inhibition Decreases the Microtubule-Binding Function of Tau Protein PMCID:    Pubmed No.:26444754 HDAC6 alleviates prion peptide-mediated neuronal death via modulating PI3K-Akt-mTOR pathway PMCID:    Pubmed No.:26507311 Lithium alleviates neurotoxic prion peptide-induced synaptic damage and neuronal death partially by the upregulation of nuclear target REST and the restoration of Wnt signaling PMCID:    Pubmed No.:28545972 Targeted inhibition of RAGE reduces amyloid-β influx across the blood-brain barrier and improves cognitive deficits in db/db mice PMCID:    Pubmed No.:29248482 Pulsed electromagnetic fields stimulate osteogenic differentiation and maturation of osteoblasts by upregulating the expression of BMPRII localized at the base of primary cilium PMCID:    Pubmed No.:27622883 Mangiferin protects mitochondrial function by preserving mitochondrial hexokinase-II in vessel endothelial cells PMCID:    Pubmed No.:28478227 CysLT1R downregulation reverses intracerebroventricular streptozotocin-induced memory impairment via modulation of neuroinflammation in mice PMCID:    Pubmed No.:27720931 Active vitamin D deficiency mediated by extracellular calcium and phosphorus results in male infertility in young mice PMCID:    Pubmed No.:25370849 Bone marrow mesenchymal stromal cells ameliorate angiogenesis and renal damage via promoting PI3k-Akt signaling pathway activation in vivo PMCID:    Pubmed No.:27210720 Cholecystokinin-8 inhibits methamphetamine-induced neurotoxicity via an anti-oxidative stress pathway PMCID:    Pubmed No.:27565679 Montelukast ameliorates streptozotocin-induced cognitive impairment and neurotoxicity in mice PMCID:    Pubmed No.:27702591 Rifampicin inhibits rotenone-induced microglial inflammation via enhancement of autophagy PMCID:    Pubmed No.:28986232 Ethanolic Ginkgo biloba leaf extract prevents renal fibrosis through Akt/mTOR signaling in diabetic nephropathy PMCID:    Pubmed No.:26547529 CERS2 Suppresses Tumor Cell Invasion and is Associated with Decreased V‐ATPase and MMP‐2/MMP‐9 Activities in Breast Cancer PMCID:    Pubmed No.:25213553 Activation of Sirtuin 3 by Silybin Attenuates Mitochondrial Dysfunction in Cisplatin-induced Acute Kidney Injury PMCID:    Pubmed No.:28424621 HucMSC exosome-transported 14-3-3ζ prevents the injury of cisplatin to HK-2 cells by inducing autophagy in vitro PMCID:    Pubmed No.:28943243 MicroRNA-222 Controls Human Pancreatic Cancer Cell Line Capan-2 Proliferation by P57 Targeting PMCID:    Pubmed No.:26535064 Arctigenin suppresses renal interstitial fibrosis in a rat model of obstructive nephropathy PMCID:    Pubmed No.:28545667 Yulangsan polysaccharide improves redox homeostasis and immune impairment in D-galactose-induced mimetic aging PMCID:    Pubmed No.:25920068 Quercetin inhibits renal cyst growth in vitro and via parenteral injection in a polycystic kidney disease mouse model PMCID:    Pubmed No.:29215110 Silence of long noncoding RNA PANDAR switches low-dose curcumin-induced senescence to apoptosis in colorectal cancer cells PMCID:    Pubmed No.:28176943 Antitumor and anti-metastatic mechanisms of Rhizoma paridis saponins in Lewis mice PMCID:    Pubmed No.:29148169 Missense mutations in the signal peptide of the porcine GH gene affect cellular synthesis and secretion PMCID:    Pubmed No.:26941166 lncRNA H19 regulates epithelial–mesenchymal transition and metastasis of bladder cancer by miR-29b-3p as competing endogenous RNA PMCID:    Pubmed No.:28779971 Enterovirus 71 induces autophagy by regulating has-miR-30a expression to promote viral replication PMCID:    Pubmed No.:26515789 Syndecan-4 Signaling Is Required for Exercise-Induced Cardiac Hypertrophy PMCID:    Pubmed No.:26835698 Etomidate Mitigates Lipopolysaccharide-Induced CD14 and TREM-1 Expression, NF-κB Activation, and Pro-inflammatory Cytokine Production in Rat Macrophages PMCID:    Pubmed No.:26383906 Zeaxanthin improves diabetes-induced cognitive deficit in rats through activiting PI3K/AKT signaling pathway PMCID:    Pubmed No.:28599877 Neuronal Soluble Fas Ligand Drives M1‐Microglia Polarization after Cerebral Ischemia PMCID:    Pubmed No.:27283206 Long-term Stress with Hyperglucocorticoidemia-induced Hepatic Steatosis with VLDL Overproduction Is Dependent on both 5-HT2 Receptor and 5-HT Synthesis in Liver PMCID:    Pubmed No.:26884719 Acute liver failure impairs function and expression of breast cancer‐resistant protein (BCRP) at rat blood–brain barrier partly via ammonia‐ROS‐ERK1/2 activation PMCID:    Pubmed No.:27168176 Neuroprotective effect of picroside II in brain injury in mice PMCID:    Pubmed No.:28078024 Overexpression of PTEN suppresses non-small-cell lung carcinoma metastasis through inhibition of integrin αVβ6 signaling PMCID:    Pubmed No.:28804548 Quantitative proteomics analysis to identify diffuse axonal injury biomarkers in rats using iTRAQ coupled LC–MS/MS PMCID:    Pubmed No.:26710722 Lipopolysaccharide derived from the digestive tract provokes oxidative stress in the liver of dairy cows fed a high-grain diet PMCID:    Pubmed No.:27865500 Mogroside IIIE, a Novel Anti-Fibrotic Compound, Reduces Pulmonary Fibrosis through Toll-Like Receptor 4 Pathways PMCID:    Pubmed No.:28280123 IGF-1/IGF-1R/ hsa-let-7c axis regulates the committed differentiation of stem cells from apical papilla PMCID:    Pubmed No.:27833148 A variation in KCNQ1 gene is associated with repaglinide efficacy on insulin resistance in Chinese Type 2 Diabetes Mellitus Patients PMCID:    Pubmed No.:27857189 Beneficial effects of paeoniflorin on non-alcoholic fatty liver disease induced by high-fat diet in rats PMCID:    Pubmed No.:28300221 MicroRNA-449a enhances radiosensitivity by downregulation of c-Myc in prostate cancer cells PMCID:    Pubmed No.:27250340 Sestrin2 Silencing Exacerbates Cerebral Ischemia/Reperfusion Injury by Decreasing Mitochondrial Biogenesis through the AMPK/PGC-1α Pathway in Rats PMCID:    Pubmed No.:27453548 Abnormally activated one-carbon metabolic pathway is associated with mtDNA hypermethylation and mitochondrial malfunction in the oocytes of polycystic gilt ovaries PMCID:    Pubmed No.:26758245 Tsc1 deficiency impairs mammary development in mice by suppression of AKT, nuclear ERα and cell-cycle-driving proteins PMCID:    Pubmed No.:26795955 P16 INK4a Deletion Ameliorated Renal Tubulointerstitial Injury in a Stress-induced Premature Senescence Model of Bmi - 1 Deficiency PMCID:    Pubmed No.:28790310 Chronic Noise Exposure Acts Cumulatively to Exacerbate Alzheimer’s Disease-Like Amyloid-β Pathology and Neuroinflammation in the Rat Hippocampus PMCID:    Pubmed No.:26251361 Anti-aging Effect of Transplanted Amniotic Membrane Mesenchymal Stem Cells in a Premature Aging Model of Bmi-1 Deficiency PMCID:    Pubmed No.:26370922 Erythropoietin alleviates hepatic insulin resistance via PPARγ-dependent AKT activation PMCID:    Pubmed No.:26643367 Curcumin attenuates high glucose-induced podocyte apoptosis by regulating functional connections between caveolin-1 phosphorylation and ROS PMCID:    Pubmed No.:26838071 Thymic derived iPs cells can be differentiated into cardiomyocytes PMCID:    Pubmed No.:25961536 NOK mediates glycolysis and nuclear PDC associated histone acetylation PMCID:    Pubmed No.:28410146 Cardioprotection by combination of three compounds from ShengMai preparations in mice with myocardial ischemia/reperfusion injury through AMPK activation-mediated mitochondrial fission PMCID:    Pubmed No.:27869201 Hypoxia-induced vasculogenic mimicry formation in human colorectal cancer cells: Involvement of HIF-1a, Claudin-4, and E-cadherin and Vimentin PMCID:    Pubmed No.:27869227 Brain-derived neurotrophic factor promotes human granulosa-like tumor cell steroidogenesis and proliferation by activating the FSH receptor-mediated signaling pathway PMCID:    Pubmed No.:28282971 Inhibition of melanogenesis by jineol from Scolopendra subspinipes mutilans via MAP-Kinase mediated MITF downregulation and the proteasomal degradation of tyrosinase PMCID:    Pubmed No.:28393917 Fucoxanthin provides neuroprotection in models of traumatic brain injury via the Nrf2-ARE and Nrf2-autophagy pathways PMCID:    Pubmed No.:28429775 A potential adjuvant chemotherapeutics, 18β-glycyrrhetinic acid, inhibits renal tubular epithelial cells apoptosis via enhancing BMP-7 epigenetically through targeting HDAC2 PMCID:    Pubmed No.:27145860 An inhibitor of the Keap1-Nrf2 protein-protein interaction protects NCM460 colonic cells and alleviates experimental colitis PMCID:    Pubmed No.:27215610 Overexpression of Bmi1 in Lymphocytes Stimulates Skeletogenesis by Improving the Osteogenic Microenvironment PMCID:    Pubmed No.:27373231 Effect of low-level mechanical vibration on osteogenesis and osseointegration of porous titanium implants in the repair of long bone defects PMCID:    Pubmed No.:26601709 Proteomic analysis of sheep primary testicular cells infected with bluetongue virus PMCID:    Pubmed No.:26989863 Stimulation of nitric oxide production contributes to the antiplatelet and antithrombotic effect of new peptide pENW (pGlu-Asn-Trp) PMCID:    Pubmed No.:26028472 Protective role of rhapontin in experimental pulmonary fibrosis in vitro and in vivo PMCID:    Pubmed No.:28364627 The protective effect of CDDO-Me on lipopolysaccharide-induced acute lung injury in mice PMCID:    Pubmed No.:25614226 Esculentoside A exerts anti-inflammatory activity in microglial cells PMCID:    Pubmed No.:28843178 Hyaluronan ameliorates LPS-induced acute lung injury in mice via Toll-like receptor (TLR) 4-dependent signaling pathways PMCID:    Pubmed No.:26321117 Activation of ephrinB–EphB receptor signalling in rat spinal cord contributes to maintenance of diabetic neuropathic pain PMCID:    Pubmed No.:27461472 miR-103 promotes 3T3-L1 cell adipogenesis through AKT/mTOR signal pathway with its target being MEF2D PMCID:    Pubmed No.:25400071 Modulation of miR-19 in Aluminum-Induced Neural Cell Apoptosis PMCID:    Pubmed No.:26836165 Effects of the suppression of lactate dehydrogenase A on the growth and invasion of human gastric cancer cells PMCID:    Pubmed No.:25394466 miR-34c plays a role of tumor suppressor in HEC‑1-B cells by targeting E2F3 protein PMCID:    Pubmed No.:25846116 Knockdown of RhoA expression alters ovarian cancer biological behavior in vitro and in nude mice PMCID:    Pubmed No.:26035556 Bcl-xL Genetic Modification Enhanced the Therapeutic Efficacy of Mesenchymal Stem Cell Transplantation in the Treatment of Heart Infarction PMCID:    Pubmed No.:26074971 miR-135b, upregulated in breast cancer, promotes cell growth and disrupts the cell cycle by regulating LATS2 PMCID:    Pubmed No.:26934863 Carnosic acid attenuates neuropathic pain in rat through the activation of spinal sirtuin1 and down-regulation of p66shc expression PMCID:    Pubmed No.:26804443 The mTOR promotes oxidative stress-induced apoptosis of mesangial cells in diabetic nephropathy PMCID:    Pubmed No.:29277549 Quercetin inhibited epithelial mesenchymal transition in diabetic rats, high-glucose-cultured lens, and SRA01/04 cells through transforming growth factor-β2/phosphoinositide 3-kinase/Akt pathway PMCID:    Pubmed No.:28501572 Pulsed electromagnetic fields promote osteoblast mineralization and maturation needing the existence of primary cilia PMCID:    Pubmed No.:25661534 Exosomes from Human Umbilical Cord Mesenchymal Stem Cells: Identification, Purification, and Biological Characteristics PMCID:    Pubmed No.:28105054 Synergistic Neuroprotective Effects of Two Herbal Ingredients via CREB-Dependent Pathway PMCID:    Pubmed No.:27729863 Inhibition of lung cancer in diethylnitrosamine‐induced mice by Rhizoma paridis saponins PMCID:    Pubmed No.:27991692 Inhibition of pulmonary adenoma in diethylnitrosamine-induced rats by Rhizoma paridis saponins PMCID:    Pubmed No.:26196122 Human Umbilical Cord Mesenchymal Stem Cells Protect Against SCA3 by Modulating the Level of 70 kD Heat Shock Protein PMCID:    Pubmed No.:28667374 Finding Missing Proteins from the Epigenetically Manipulated Human Cell with Stringent Quality Criteria PMCID:    Pubmed No.:26202631 Mangiferin Attenuates Renal Fibrosis Through Down‐Regulation of Osteopontin in Diabetic Rats PMCID:    Pubmed No.:25380391 Effective treatment with combination of peripheral 5‐hydroxytryptamine synthetic inhibitor and 5‐hydroxytryptamine 2 receptor antagonist on glucocorticoid‐induced whole‐body insulin resistance with hyperglycemia PMCID:    Pubmed No.:27177506 Important role of 5‐hydroxytryptamine in glucocorticoid‐induced insulin resistance in liver and intra‐abdominal adipose tissue of rats PMCID:    Pubmed No.:26816599 SIRT1 activator ameliorates the renal tubular injury induced by hyperglycemia in vivo and in vitro via inhibiting apoptosis PMCID:    Pubmed No.:27470548 Costunolide, an active sesquiterpene lactone, induced apoptosis via ROS-mediated ER stress and JNK pathway in human U2OS cells PMCID:    Pubmed No.:27133064 Roles of Pannexin-1 Channels in Inflammatory Response through the TLRs/NF-Kappa B Signaling Pathway Following Experimental Subarachnoid Hemorrhage in Rats PMCID:    Pubmed No.:28634441 Supplementing the maternal diet of rats with butyrate enhances mitochondrial biogenesis in the skeletal muscles of weaned offspring PMCID:    Pubmed No.:28091351 Sinomenine Provides Neuroprotection in Model of Traumatic Brain Injury via the Nrf2–ARE Pathway PMCID:    Pubmed No.:28066165 Inhibition of allicin in Eca109 and EC9706 cells via G2/M phase arrest and mitochondrial apoptosis pathway PMCID:    Pubmed No.:36500466 Withanolides isolated from Nicandra physaloides protect liver cells against oxidative stress-induced damage PMCID:    Pubmed No.:30414878 Autophagy regulates biliary differentiation of hepatic progenitor cells through Notch1 signaling pathway PMCID:    Pubmed No.:27259983 Lipopolysaccharide induces the differentiation of hepatic progenitor cells into myofibroblasts via activation of the Hedgehog signaling pathway PMCID:    Pubmed No.:28562206 LPS-induced CXCR4-dependent migratory properties and a mesenchymal-like phenotype of colorectal cancer cells PMCID:    Pubmed No.:26745593 Esculentoside A suppresses lipopolysaccharide-induced pro-inflammatory molecule production partially by casein kinase 2 PMCID:    Pubmed No.:28027904 YiQiFuMai Powder Injection ameliorates the oxygen-glucose deprivation-induced brain microvascular endothelial barrier dysfunction associated with the NF-κB and ROCK1/MLC signaling pathways PMCID:    Pubmed No.:26915982 Chotosan improves Aβ1–42-induced cognitive impairment and neuroinflammatory and apoptotic responses through the inhibition of TLR-4/NF-κB signaling in mice PMCID:    Pubmed No.:26994819 Huangkui capsule attenuates renal fibrosis in diabetic nephropathy rats through regulating oxidative stress and p38MAPK/Akt pathways, compared to α-lipoic acid PMCID:    Pubmed No.:26226437 Modulation of gut microbiota contributes to curcumin-mediated attenuation of hepatic steatosis in rats PMCID:    Pubmed No.:28341485 Suppression of GLI sensitizes medulloblastoma cells to mitochondria-mediated apoptosis PMCID:    Pubmed No.:27601167 Orientin alleviates cognitive deficits and oxidative stress in Aβ1–42-induced mouse model of Alzheimer's disease PMCID:    Pubmed No.:25497709 Drosophila miR-964 modulates Toll signaling pathway in response to bacterial infection PMCID:    Pubmed No.:28823799 Resveratrol Ameliorates the Anxiety- and Depression-Like Behavior of Subclinical Hypothyroidism Rat: Possible Involvement of the HPT Axis, HPA Axis, and Wnt/β-Catenin Pathway PMCID:    Pubmed No.:27252679 Involvement of pregnane X receptor in the suppression of carboxylesterases by metformin in vivo and in vitro, mediated by the activation of AMPK and JNK signaling pathway PMCID:    Pubmed No.:28238946 CRHR1 Mediates the Up-Regulation of Synapsin I Induced by Nesfatin-1 Through ERK 1/2 Signaling in SH-SY5Y Cells PMCID:    Pubmed No.:28608000 IL-33 Expression in the Cerebral Cortex Following Experimental Subarachnoid Hemorrhage in Rats PMCID:    Pubmed No.:25417195 Expression of Cytoplasmic Gelsolin in Rat Brain After Experimental Subarachnoid Hemorrhage PMCID:    Pubmed No.:25744577 Expression and Cell Distribution of SENP3 in Brain Tissue After Traumatic Brain Injury in Mice: A Pilot Study PMCID:    Pubmed No.:25744577 Traumatic Brain Injury-Induced Neuronal Apoptosis is Reduced Through Modulation of PI3K and Autophagy Pathways in Mouse by FTY720 PMCID:    Pubmed No.:26099903 Loss of Myh14 Increases Susceptibility to Noise-Induced Hearing Loss in CBA/CaJ Mice PMCID:    Pubmed No.:28101381 Bmi-1 plays a critical role in the protection from acute tubular necrosis by mobilizing renal stem/progenitor cells PMCID:    Pubmed No.:27871857 Gastrin-releasing peptide induces monocyte adhesion to vascular endothelium by upregulating endothelial adhesion molecules PMCID:    Pubmed No.:28093230 Involvement of WNK1-mediated potassium channels in the sexual dimorphism of blood pressure PMCID:    Pubmed No.:28237360 MKK4 activates non-canonical NFκB signaling by promoting NFκB2-p100 processing PMCID:    Pubmed No.:28733031 NFAT5 promotes proliferation and migration of lung adenocarcinoma cells in part through regulating AQP5 expression PMCID:    Pubmed No.:26299924 MiR-139-5p inhibits the biological function of breast cancer cells by targeting Notch1 and mediates chemosensitivity to docetaxel PMCID:    Pubmed No.:26299922 Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression PMCID:    Pubmed No.:26936624 Targeted CDX2 expression inhibits aggressive phenotypes of colon cancer cells in vitro and in vivo PMCID:    Pubmed No.:28627695 Dihydromyricetin modulates p62 and autophagy crosstalk with the Keap-1/Nrf2 pathway to alleviate ethanol-induced hepatic injury PMCID:    Pubmed No.:28419832 FTY720 induces autophagy-related apoptosis and necroptosis in human glioblastoma cells PMCID:    Pubmed No.:25939952 Autophagy Inhibition Overcomes the Antagonistic Effect Between Gefitinib and Cisplatin in Epidermal Growth Factor Receptor Mutant Non–Small-Cell Lung Cancer Cells PMCID:    Pubmed No.:25979647 The Central Role of IFI204 in IFN-β Release and Autophagy Activation during Mycobacterium bovis Infection PMCID:    Pubmed No.:28529930 NOAD, a novel nitric oxide donor, induces G2/M phase arrest and apoptosis in human hepatocellular carcinoma Bel-7402 cells PMCID:    Pubmed No.:26001517 Inhibition of green tea polyphenol EGCG((−)-epigallocatechin-3-gallate) on the proliferation of gastric cancer cells by suppressing canonical wnt/β-catenin signalling pathway PMCID:    Pubmed No.:27338284 Meat proteins had different effects on oligopeptide transporter PEPT1 in the small intestine of young rats PMCID:    Pubmed No.:27455889 α, γ-Mangostins Induce Autophagy and Show Synergistic Effect with Gemcitabine in Pancreatic Cancer Cell Lines PMCID:    Pubmed No.:28822990 Comparative analysis of the serum proteome for biomarker discovery to reveal hepatotoxicity induced by iron ion radiation in mice PMCID:    Pubmed No.:27815023 Protective effect of coptisine free base on indomethacin-induced gastric ulcers in rats: Characterization of potential molecular mechanisms PMCID:    Pubmed No.:29223540 Knockdown of hippocampal cysteinyl leukotriene receptor 1 prevents depressive behavior and neuroinflammation induced by chronic mild stress in mice PMCID:    Pubmed No.:26546369 Silencing of GP73 inhibits invasion and metastasis via suppression of epithelial-mesenchymal transition in hepatocellular carcinoma PMCID:    Pubmed No.:28075476 Stimulation of peroxisome proliferator-activated receptor γ inhibits estrogen receptor α transcriptional activity in endometrial carcinoma cells PMCID:    Pubmed No.:25592200 EVI5 is a novel independent prognostic predictor in hepatocellular carcinoma after radical hepatectomy PMCID:    Pubmed No.:28765910 Huaier extract enhances the treatment efficacy of paclitaxel in breast cancer cells via the NF-κB/IκBα pathway PMCID:    Pubmed No.:29039556 Isoliquiritigenin inhibits the proliferation and induces the differentiation of human glioma stem cells PMCID:    Pubmed No.:29251326 α-Lipoic acid attenuates LPS-induced liver injury by improving mitochondrial function in association with GR mitochondrial DNA occupancy PMCID:    Pubmed No.:26133658 Neuroprotective Effect of Sodium Butyrate against Cerebral Ischemia/Reperfusion Injury in Mice PMCID:    Pubmed No.:26064905 Regulatory role of miR-125a/b in the suppression by selenium of cadmium-induced apoptosis via the mitochondrial pathway in LLC-PK1 cells PMCID:    Pubmed No.:26607349 Downregulation of DEC1 contributes to the neurotoxicity induced by MPP+ by suppressing PI3K/Akt/GSK3β pathway PMCID:    Pubmed No.:28734031 Phosphorylated heat shock protein 27 promotes lipid clearance in hepatic cells through interacting with STAT3 and activating autophagy PMCID:    Pubmed No.:27185187 GRP78 is implicated in the modulation of tumor aerobic glycolysis by promoting autophagic degradation of IKKβ PMCID:    Pubmed No.:25748049 Inflammasome-independent NLRP3 is required for epithelial-mesenchymal transition in colon cancer cells PMCID:    Pubmed No.:26968633 Bmi1 plays an important role in dentin and mandible homeostasis by maintaining redox balance PMCID:    Pubmed No.:27904674 Tetrahydrocurcumin reduces oxidative stress-induced apoptosis via the mitochondrial apoptotic pathway by modulating autophagy in rats after traumatic brain injury PMCID:    Pubmed No.:28386319 Pyrroloquinoline quinone prevents testosterone deficiency-induced osteoporosis by stimulating osteoblastic bone formation and inhibiting osteoclastic bone resorption PMCID:    Pubmed No.:28386349 The protective effect of astaxanthin on learning and memory deficits and oxidative stress in a mouse model of repeated cerebral ischemia/reperfusion PMCID:    Pubmed No.:28479214 The effect of monascin on hematoma clearance and edema after intracerebral hemorrhage in rats PMCID:    Pubmed No.:28655601 Heat Stress Reduces Sperm Motility via Activation of Glycogen Synthase Kinase-3α and Inhibition of Mitochondrial Protein Import PMCID:    Pubmed No.:29018353 Mogroside IVE attenuates experimental liver fibrosis in mice and inhibits HSC activation through downregulating TLR4-mediated pathways PMCID:    Pubmed No.:29268190 Bergapten prevents lipopolysaccharide-induced inflammation in RAW264.7 cells through suppressing JAK/STAT activation and ROS production and increases the survival rate of mice after LPS challenge PMCID:    Pubmed No.:28511114 Resokaempferol-mediated anti-inflammatory effects on activated macrophages via the inhibition of JAK2/STAT3, NF-κB and JNK/p38 MAPK signaling pathways PMCID:    Pubmed No.:27261558 Synthesis, antiproliferative and apoptosis-inducing effects of novel asiatic acid derivatives containing α-aminophosphonates PMCID:    Pubmed No.:24262379 MiR-146a modulates macrophage polarization by inhibiting Notch1 pathway in RAW264.7 macrophages PMCID:    Pubmed No.:26800097 Inhalation of ambroxol inhibits cigarette smoke-induced acute lung injury in a mouse model by inhibiting the Erk pathway PMCID:    Pubmed No.:26881857 Role of NLRC5 in progression and reversal of hepatic fibrosis PMCID:    Pubmed No.:26806094 HZ-6d targeted HERC5 to regulate p53 ISGylation in human hepatocellular carcinoma PMCID:    Pubmed No.:28919514 X-11-5-27, a daidzein derivative, inhibits NLRP3 inflammasome activity via promoting autophagy PMCID:    Pubmed No.:28942022 Up-regulation of Tight-Junction Proteins by p38 Mitogen-Activated Protein Kinase/p53 Inhibition Leads to a Reduction of Injury to the Intestinal Mucosal Barrier in Severe Acute Pancreatitis PMCID:    Pubmed No.:27171513 RAGE-NF-κB-PPARγ Signaling is Involved in AGEs-Induced Upregulation of Amyloid-β Influx Transport in an In Vitro BBB Model PMCID:    Pubmed No.:28871412 The Pyk2/MCU pathway in the rat middle cerebral artery occlusion model of ischemic stroke PMCID:    Pubmed No.:28916471 MicroRNA-150 negatively regulates the function of CD4+ T cells through AKT3/Bim signaling pathway PMCID:    Pubmed No.:27329362 MicroRNA-20a negatively regulates expression of NLRP3-inflammasome by targeting TXNIP in adjuvant-induced arthritis fibroblast-like synoviocytes PMCID:    Pubmed No.:26934991 Tetramethylpyrazine phosphate and borneol combination therapy synergistically attenuated ischemia-reperfusion injury of the hypothalamus and striatum via regulation of apoptosis and autophagy in a rat model PMCID:    Pubmed No.:29218081 Inhibition of SENP3 by lentivirus induces suppression of apoptosis in experimental subarachnoid hemorrhage in rats PMCID:    Pubmed No.:26151898 Fisetin alleviates early brain injury following experimental subarachnoid hemorrhage in rats possibly by suppressing TLR 4/NF-κB signaling pathway PMCID:    Pubmed No.:26475978 Simvastatin ameliorates memory impairment and neurotoxicity in streptozotocin-induced diabetic mice PMCID:    Pubmed No.:28499972 Regulation of RAW 264.7 cell-mediated immunity by polysaccharides from Agaricus blazei Murill via the MAPK signal transduction pathway PMCID:    Pubmed No.:28322382 Lipopolysaccharide markedly changes glucose metabolism and mitochondrial function in the longissimus muscle of pigs PMCID:    Pubmed No.:26863995 Ginsenosides Regulate PXR/NF-κB Signaling and Attenuate Dextran Sulfate Sodium–Induced Colitis PMCID:    Pubmed No.:25986850 Relaxin inhibits cardiac fibrosis and endothelial–mesenchymal transition via the Notch pathway PMCID:    Pubmed No.:26316699 Dexmedetomidine reduces the neuronal apoptosis related to cardiopulmonary bypass by inhibiting activation of the JAK2–STAT3 pathway PMCID:    Pubmed No.:29033541 Comparative proteomics reveals the underlying toxicological mechanism of low sperm motility induced by iron ion radiation in mice PMCID:    Pubmed No.:27460355 Comparative proteomic profiling and possible toxicological mechanism of acute injury induced by carbon ion radiation in pubertal mice testes PMCID:    Pubmed No.:26257270 Protective effect of different flavonoids against endothelial senescence via NLRP3 inflammasome PMCID:    Pubmed No.:37777764 Blueberry anthocyanins extract inhibits acrylamide-induced diverse toxicity in mice by preventing oxidative stress and cytochrome P450 2E1 activation PMCID:    Pubmed No.:32982731 Nrf2 is essential for the anti-inflammatory effect of carbon monoxide in LPS-induced inflammation PMCID:    Pubmed No.:26049867 Apelin-13 as a novel target for intervention in secondary injury after traumatic brain injury PMCID:    Pubmed No.:27630697 Compound edaravone alleviates lipopolysaccharide (LPS)-induced acute lung injury in mice PMCID:    Pubmed No.:28552343 Anti-inflammatory activity of coptisine free base in mice through inhibition of NF-κB and MAPK signaling pathways PMCID:    Pubmed No.:28648405 Gastrin-releasing peptide promotes the migration of vascular smooth muscle cells through upregulation of matrix metalloproteinase-2 and -9 PMCID:    Pubmed No.:29065966 MALAT1 promoted invasiveness of gastric adenocarcinoma PMCID:    Pubmed No.:28077118 Folate deprivation induces cell cycle arrest at G0/G1 phase and apoptosis in hippocampal neuron cells through down-regulation of IGF-1 signaling pathway PMCID:    Pubmed No.:27592453 Metformin ameliorates the development of experimental autoimmune encephalomyelitis by regulating T helper 17 and regulatory T cells in mice PMCID:    Pubmed No.:26943960 Protective effects of Shanxi aged vinegar against hydrogen peroxide-induced oxidative damage in LO2 cells through Nrf2-mediated antioxidant responses PMCID:    Pubmed No.:37200790  Differential Proteomics Reveals the Potential Injury Mechanism Induced by Heavy Ion Radiation in Mice Ovaries PMCID:    Pubmed No.:28494840 Serum response factor induces endothelial-mesenchymal transition in glomerular endothelial cells to aggravate proteinuria in diabetic nephropathy PMCID:    Pubmed No.:27565710 l-Theanine attenuates cadmium-induced neurotoxicity through the inhibition of oxidative damage and tau hyperphosphorylation PMCID:    Pubmed No.:27649883 Icariin alters the expression of glucocorticoid receptor, FKBP5 and SGK1 in rat brains following exposure to chronic mild stress PMCID:    Pubmed No.:27221032 iTRAQ-based quantitative proteomic analysis of the anti-apoptotic effect of hyperin, which is mediated by Mcl-1 and Bid, in H2O2-injured EA.hy926 cells PMCID:    Pubmed No.:26935776 miR-30a inhibits the biological function of breast cancer cells by targeting Notch1 PMCID:    Pubmed No.:28765900 MicroRNA-145 inhibits hepatic stellate cell activation and proliferation by targeting ZEB2 through Wnt/β-catenin pathway PMCID:    Pubmed No.:27289031 Daphnetin reduces endotoxin lethality in mice and decreases LPS-induced inflammation in Raw264.7 cells via suppressing JAK/STATs activation and ROS production PMCID:    Pubmed No.:28409189 2,3,5,4′‐tetrahydroxystilbene‐2‐O‐β‐d‐glucoside protects human umbilical vein endothelial cells against lysophosphatidylcholine‐induced apoptosis by upregulating superoxide dismutase and glutathione peroxidase PMCID:    Pubmed No.:25382724 TSG attenuates LPC‐induced endothelial cells inflammatory damage through notch signaling inhibition PMCID:    Pubmed No.:26662286 miR-375 exhibits a more effective tumor-suppressor function in laryngeal squamous carcinoma cells by regulating KLF4 expression compared with simple co-transfection of miR-375 and miR-206 PMCID:    Pubmed No.:27279635 Downregulation of miR-129-2 by promoter hypermethylation regulates breast cancer cell proliferation and apoptosis PMCID:    Pubmed No.:26935022 Deubiquitinase USP9X promotes cell migration, invasion and inhibits apoptosis of human pancreatic cancer PMCID:    Pubmed No.:29130109 Methylglyoxal Impairs Insulin Secretion of Pancreatic β-Cells through Increased Production of ROS and Mitochondrial Dysfunction Mediated by Upregulation of UCP2 and MAPKs PMCID:    Pubmed No.:26779540 Increased Expression of Caspase-12 After Experimental Subarachnoid Hemorrhage PMCID:    Pubmed No.:27718045 Ursolic Acid Ameliorates Early Brain Injury After Experimental Traumatic Brain Injury in Mice by Activating the Nrf2 Pathway PMCID:    Pubmed No.:27734181 dl -3- n -Butylphthalide (NBP) Provides Neuroprotection in the Mice Models After Traumatic Brain Injury via Nrf2-ARE Signaling Pathway PMCID:    Pubmed No.:28214984 Folic Acid Protected Neural Cells Against Aluminum-Maltolate-Induced Apoptosis by Preventing miR-19 Downregulation PMCID:    Pubmed No.:27113042 Tetramethylpyrazine induces SH-SY5Y cell differentiation toward the neuronal phenotype through activation of the PI3K/Akt/Sp1/TopoIIβ pathway PMCID:    Pubmed No.:26518113 Synthesis and cytotoxicity evaluation of 3-amino-2-hydroxypropoxyisoflavone derivatives PMCID:    Pubmed No.:27473965 Tetrandrine inhibits migration and invasion of rheumatoid arthritis fibroblast-like synoviocytes through down-regulating the expressions of Rac1, Cdc42, and RhoA GTPases and activation of the PI3K/Akt and JNK signaling pathways PMCID:    Pubmed No.:26614458 C-reactive protein inhibits high-molecular-weight adiponectin expression in 3T3-L1 adipocytes via PI3K/Akt pathway PMCID:    Pubmed No.:26812237 SHC1 sensitizes cancer cells to the 8-Cl-cAMP treatment PMCID:    Pubmed No.:26043699 Annosquacin B induces mitochondrial apoptosis in multidrug resistant human breast cancer cell line MCF-7/ADR through selectively modulating MAPKs pathways PMCID:    Pubmed No.:27450387 Helicobacter pylori-infected MSCs acquire a pro-inflammatory phenotype and induce human gastric cancer migration by promoting EMT in gastric cancer cells PMCID:    Pubmed No.:26870232 ONTD induces growth arrest and apoptosis of human hepatoma Bel-7402 cells though a peroxisome proliferator-activated receptor γ-dependent pathway PMCID:    Pubmed No.:28834734 Curcumin inhibits osteoclastogenic potential in PBMCs from rheumatoid arthritis patients via the suppression of MAPK/RANK/c-Fos/NFATc1 signaling pathways PMCID:    Pubmed No.:27572279 microRNA‑99a inhibits cell proliferation, colony formation ability, migration and invasion by targeting fibroblast growth factor receptor 3 in prostate cancer PMCID:    Pubmed No.:25352177 Long non‑coding RNA‑GAS5 acts as a tumor suppressor in bladder transitional cell carcinoma via regulation of chemokine (C‑C motif) ligand 1 expression PMCID:    Pubmed No.:26548923 Icariin ameliorates dexamethasone‑induced bone deterioration in an experimental mouse model via activation of microRNA‑186 inhibition of cathepsin K PMCID:    Pubmed No.:29257214 Clostridium butyricum exerts a neuroprotective effect in a mouse model of traumatic brain injury via the gut‐brain axis PMCID:    Pubmed No.:29193450 Inhibition of IRF8 Negatively Regulates Macrophage Function and Impairs Cutaneous Wound Healing PMCID:    Pubmed No.:27709315 Syndecan-4 regulates the bFGF-induced chemotactic migration of endothelial cells PMCID:    Pubmed No.:27541034 Sonic hedgehog-mediated epithelial-mesenchymal transition in renal tubulointerstitial fibrosis PMCID:    Pubmed No.:27035418 Tougu Xiaotong formula induces chondrogenic differentiation in association with transforming growth factor-β1 and promotes proliferation in bone marrow stromal cells PMCID:    Pubmed No.:25543835 Sulfiredoxin-1 exerts anti-apoptotic and neuroprotective effects against oxidative stress-induced injury in rat cortical astrocytes following exposure to oxygen-glucose deprivation and hydrogen peroxide PMCID:    Pubmed No.:25955519 Transgenic expression of ephrinB2 in periodontal ligament stem cells (PDLSCs) modulates osteogenic differentiation via signaling crosstalk between ephrinB2 and EphB4 in PDLSCs and between PDLSCs and pre‐osteoblasts within co‐culture PMCID:    Pubmed No.:27763659 Effect of Acute and Chronic Exposure to High Altitude on the Aerobic and Anaerobic Metabolism in Rats PMCID:    Pubmed No.:26640758 Lipopolysaccharide significantly influences the hepatic triglyceride metabolism in growing pigs PMCID:    Pubmed No.:26121977 Silymarin alleviates hepatic oxidative stress and protects against metabolic disorders in high-fat diet-fed mice PMCID:    Pubmed No.:26758315 Panaxatriol saponins promotes angiogenesis and enhances cerebral perfusion after ischemic stroke in rats PMCID:    Pubmed No.:28114983 Nitro-oleic acid ameliorates oxygen and glucose deprivation/re-oxygenation triggered oxidative stress in renal tubular cells via activation of Nrf2 and suppression of NADPH oxidase PMCID:    Pubmed No.:27545328 Arctigenin suppresses transforming growth factor-β1-induced expression of monocyte chemoattractant protein-1 and the subsequent epithelial–mesenchymal transition through reactive oxygen species-dependent ERK/NF-κB signaling pathway in renal tubular epithe PMCID:    Pubmed No.:25968940 Bursopentin (BP5) Protects Dendritic Cells from Lipopolysaccharide-Induced Oxidative Stress for Immunosuppression PMCID:    Pubmed No.:25659113 miR-101 Suppresses Vascular Endothelial Growth Factor C That Inhibits Migration and Invasion and Enhances Cisplatin Chemosensitivity of Bladder Cancer Cells PMCID:    Pubmed No.:25658842 In Ovo Injection of Betaine Affects Hepatic Cholesterol Metabolism through Epigenetic Gene Regulation in Newly Hatched Chicks PMCID:    Pubmed No.:25860502 Inhibition of leukotriene B4 synthesis protects against early brain injury possibly via reducing the neutrophil-generated inflammatory response and oxidative stress after subarachnoid hemorrhage in rats PMCID:    Pubmed No.:29133197 FTY720 inhibits the Nrf2/ARE pathway in human glioblastoma cell lines and sensitizes glioblastoma cells to temozolomide PMCID:    Pubmed No.:29128799 Protective Effects of Quercetin on Mitochondrial Biogenesis in Experimental Traumatic Brain Injury via the Nrf2 Signaling Pathway PMCID:    Pubmed No.:27780244 Tropomyosin-1 acts as a potential tumor suppressor in human oral squamous cell carcinoma PMCID:    Pubmed No.:28182650 Oridonin Attenuates Synaptic Loss and Cognitive Deficits in an Aβ1–42-Induced Mouse Model of Alzheimer’s Disease PMCID:    Pubmed No.:26974541 Expression and cell distribution of leukotriene B4 receptor 1 in the rat brain cortex after experimental subarachnoid hemorrhage PMCID:    Pubmed No.:27725151 Astaxanthin reduces matrix metalloproteinase-9 expression and activity in the brain after experimental subarachnoid hemorrhage in rats PMCID:    Pubmed No.:26210617 Thymol improves high-fat diet-induced cognitive deficits in mice via ameliorating brain insulin resistance and upregulating NRF2/HO-1 pathway PMCID:    Pubmed No.:27761760 PPARδ agonist GW0742 ameliorates Aβ 1–42 -induced hippocampal neurotoxicity in mice PMCID:    Pubmed No.:26864581 Syndecan-4 shedding impairs macrovascular angiogenesis in diabetes mellitus PMCID:    Pubmed No.:27018253 Sulfiredoxin-1 Attenuates Oxidative Stress via Nrf2/ARE Pathway and 2-Cys Prdxs After Oxygen-Glucose Deprivation in Astrocytes PMCID:    Pubmed No.:25407820 Rho Kinase Inhibitor, Fasudil, Attenuates Contrast‐induced Acute Kidney Injury PMCID:    Pubmed No.:28929640 The possible role of liver kinase B1 in hydroquinone‐induced toxicity of murine fetal liver and bone marrow hematopoietic stem cells PMCID:    Pubmed No.:25534963 Expression of Transcription Factor FOXO3a is Decreased in Patients with Ulcerative Colitis PMCID:    Pubmed No.:26481742 Heparin-Binding Epidermal Growth Factor-Like Growth Factor Enhances Aquaporin 3 Expression and Function During Mouse Embryo Implantation PMCID:    Pubmed No.:27436370 Parasympathectomy increases resting salivary secretion in normal and irradiated submandibular glands of rats PMCID:    Pubmed No.:28084660 IL-27 regulates the adherence, proliferation, and migration of MSCs and enhances their regulatory effects on Th1 and Th2 subset generations PMCID:    Pubmed No.:28612255 LXW7 ameliorates focal cerebral ischemia injury and attenuates inflammatory responses in activated microglia in rats PMCID:    Pubmed No.:27533766 The Involvement of NR2B and tau Protein in MG132-Induced CREB Dephosphorylation PMCID:    Pubmed No.:28424976 The Synergic Effect of Tetramethylpyrazine Phosphate and Borneol for Protecting Against Ischemia Injury in Cortex and Hippocampus Regions by Modulating Apoptosis and Autophagy PMCID:    Pubmed No.:28779236 Effect of β‐catenin silencing in overcoming radioresistance of head and neck cancer cells by antagonizing the effects of AMPK on Ku70/Ku80 PMCID:    Pubmed No.:26713771 The angiogenic variation of skeletal site-specific human BMSCs from same alveolar cleft patients: a comparative study PMCID:    Pubmed No.:26846721 Human amnion mesenchymal stem cells promote proliferation and osteogenic differentiation in human bone marrow mesenchymal stem cells PMCID:    Pubmed No.:25432786 Depleted aldehyde dehydrogenase 1A1 (ALDH1A1) reverses cisplatin resistance of human lung adenocarcinoma cell A549/DDP PMCID:    Pubmed No.:27813328 MicroRNA-9 regulates cardiac fibrosis by targeting PDGFR-β in rats PMCID:    Pubmed No.:26896308 miR-31 promotes proliferation of colon cancer cells by targeting E2F2 PMCID:    Pubmed No.:25362258 Phosphoglycerate mutase 1 knockdown inhibits prostate cancer cell growth, migration, and invasion PMCID:    Pubmed No.:29271400 Neuroprotection by peripheral nerve electrical stimulation and remote postconditioning against acute experimental ischaemic stroke PMCID:    Pubmed No.:25819636 Effects of Ru(CO)3Cl-glycinate on the developmental toxicities induced by X-ray and carbon-ion irradiation in zebrafish embryos PMCID:    Pubmed No.:27837686 HNF-4alpha Negatively Regulates Hepcidin Expression Through BMPR1A in HepG2 Cells PMCID:    Pubmed No.:27660075 Investigations of 99mTc-labeled glucarate as a SPECT radiotracer for non-small cell lung cancer (NSCLC) and potential tumor uptake mechanism PMCID:    Pubmed No.:29467852 Expression Profiles of IGF-1R Gene and Polymorphisms of its Regulatory Regions in Different Pig Breeds PMCID:    Pubmed No.:27229719 Inhibitory Effects of Isorhamnetin on the Invasion of Human Breast Carcinoma Cells by Downregulating the Expression and Activity of Matrix Metalloproteinase-2/9 PMCID:    Pubmed No.:26359917 5-Aminosalicylic acid inhibits inflammatory responses by suppressing JNK and p38 activity in murine macrophages PMCID:    Pubmed No.:28071183 Tumor‑suppressing effects of microRNA‑429 in human renal cell carcinoma via the downregulation of Sp1 PMCID:    Pubmed No.:27698878 Fibronectin induces epithelial-mesenchymal transition in human breast cancer MCF-7 cells via activation of calpain PMCID:    Pubmed No.:28521486 Effect of hyperthermic CO2-treated dendritic cell-derived exosomes on the human gastric cancer AGS cell line PMCID:    Pubmed No.:26170979 Molecular Characterization of Equine APRIL and its Expression Analysis During the Adipogenic Differentiation of Equine Adipose-Derived Stem Cell In Vitro PMCID:    Pubmed No.:27565870 Polypeptides from the Skin of Rana chensinensis Exert the Antioxidant and Antiapoptotic Activities on HaCaT Cells PMCID:    Pubmed No.:27385409 Dehydroabietic Acid Derivative QC4 Induces Gastric Cancer Cell Death via Oncosis and Apoptosis PMCID:    Pubmed No.:27057539 Citalopram Ameliorates Impairments in Spatial Memory and Synaptic Plasticity in Female 3xTgAD Mice PMCID:    Pubmed No.:29075638 Involvement of the PI3K/Akt/NF-κB Signaling Pathway in the Attenuation of Severe Acute Pancreatitis-Associated Acute Lung Injury by Sedum sarmentosum Bunge Extract PMCID:    Pubmed No.:29359164 Melatonin reduces hypoxic-ischaemic (HI) induced autophagy and apoptosis: An in vivo and in vitro investigation in experimental models of neonatal HI brain injury PMCID:    Pubmed No.:28341477 The neuroprotective effect of apelin-13 in a mouse model of intracerebral hemorrhage PMCID:    Pubmed No.:27343409 Dietary betaine supplementation in hens modulates hypothalamic expression of cholesterol metabolic genes in F1 cockerels through modification of DNA methylation PMCID:    Pubmed No.:29247843 Leptin treatment prevents long-term abnormalities in cognition, seizure threshold, hippocampal mossy fiber sprouting and ZnT3/CB-D28k expression in a rat developmental “twist” seizure model PMCID:    Pubmed No.:29287786 Self-Assembling RADA16-I Peptide Hydrogel Scaffold Loaded with Tamoxifen for Breast Reconstruction PMCID:    Pubmed No.:28691024 Amniotic Mesenchymal Stem Cells Can Enhance Angiogenic Capacity via MMPs In Vitro and In Vivo PMCID:    Pubmed No.:26491665 Resveratrol ameliorates chronic unpredictable mild stress-induced depression-like behavior: involvement of the HPA axis, inflammatory markers, BDNF, and Wnt/β-catenin pathway in rats PMCID:    Pubmed No.:29138567 Swimming training alleviated insulin resistance through Wnt3a/β-catenin signaling in type 2 diabetic rats PMCID:    Pubmed No.:29299199 Whole Body Vibration Improves Insulin Resistance in db/db Mice: Amelioration of Lipid Accumulation and Oxidative Stress PMCID:    Pubmed No.:26945578 H2S inhibits apo(a) expression and secretion through PKCα/FXR and Akt/HNF4α pathways in HepG2 cells PMCID:    Pubmed No.:27298021 Phenotype transformation of immortalized NCM460 colon epithelial cell line by TGF-β1 is associated with chromosome instability PMCID:    Pubmed No.:27401062 Silencing thioredoxin1 exacerbates damage of astrocytes exposed to OGD/R by aggravating apoptosis through the Actin–Ras2–cAMP–PKA pathway PMCID:    Pubmed No.:29073813 Resveratrol inhibits phosphorylation within the signal transduction and activator of transcription 3 signaling pathway by activating sirtuin 1 in SW1353 chondrosarcoma cells PMCID:    Pubmed No.:27484919 VPA and MEL induce apoptosis by inhibiting the Nrf2-ARE signaling pathway in TMZ-resistant U251 cells PMCID:    Pubmed No.:28560379 Effects of p53 on aldosterone-induced mesangial cell apoptosis in vivo and in vitro PMCID:    Pubmed No.:27109859 Glycolysis inhibitor 2-deoxy-D-glucose suppresses carcinogen-induced rat hepatocarcinogenesis by restricting cancer cell metabolism PMCID:    Pubmed No.:25394852 Astragalus and Paeoniae Radix Rubra extract (APE) inhibits hepatic stellate cell activation by modulating transforming growth factor-β/smad pathway PMCID:    Pubmed No.:25435153 Protein kinase Cα stimulates hypoxia‑induced pulmonary artery smooth muscle cell proliferation in rats through activating the extracellular signal‑regulated kinase 1/2 pathway PMCID:    Pubmed No.:28901444 Bone marrow-derived mesenchymal stem cells inhibit the proliferation of hepatic stellate cells by inhibiting the transforming growth factor β pathway PMCID:    Pubmed No.:26458849 The Inhibitory Effect of Eplerenone on Cell Proliferation in the Contralateral Kidneys of Rats with Unilateral Ureteral Obstruction PMCID:    Pubmed No.:28402979 Glioma targeting peptide in combination with the P53 C terminus inhibits glioma cell proliferation in vitro PMCID:    Pubmed No.:28879517 5-HT 2 receptor mediates high-fat diet-induced hepatic steatosis and very low density lipoprotein overproduction in rats PMCID:    Pubmed No.:27133527 Sarsasapogenin suppresses Aβ overproduction induced by high glucose in HT-22 cells PMCID:    Pubmed No.:29275517 Erythroblast transformation-specific 2 correlates with vascular smooth muscle cell apoptosis in rat heterotopic heart transplantation model PMCID:    Pubmed No.:27621856 Prenatal betaine exposure modulates hypothalamic expression of cholesterol metabolic genes in cockerels through modifications of DNA methylation PMCID:    Pubmed No.:27965408 YGS40, an active fraction of Yi-Gan San, reduces hydrogen peroxide-induced apoptosis in PC12 cells PMCID:    Pubmed No.:26073340 Connective tissue growth factor induces tubular epithelial to mesenchymal transition through the activation of canonical Wnt signaling in vitro PMCID:    Pubmed No.:25296105 Glucocorticoid receptor-mediated insulin-like growth factor-I transcriptional regulation in BeWo trophoblast cells before and after syncytialisation PMCID:    Pubmed No.:27500692 Folate deprivation modulates the expression of autophagy- and circadian-related genes in HT-22 hippocampal neuron cells through GR-mediated pathway PMCID:    Pubmed No.:27133904 Short-Term Hypoxia Accelerates Bone Loss in Ovariectomized Rats by Suppressing Osteoblastogenesis but Enhancing Osteoclastogenesis PMCID:    Pubmed No.:27550548 Alpha-Lipoic Acid Alleviates Acute Inflammation and Promotes Lipid Mobilization During the Inflammatory Response in White Adipose Tissue of Mice PMCID:    Pubmed No.:27531126 Heat stress inhibits proliferation, promotes growth, and induces apoptosis in cultured Lantang swine skeletal muscle satellite cells PMCID:    Pubmed No.:26055917 Silencing platelet‑derived growth factor receptor‑β enhances the radiosensitivity of C6 glioma cells in vitro and in vivo PMCID:    Pubmed No.:28693172 Effect of the p53α gene on the chemosensitivity of the H1299 human lung adenocarcinoma cell line PMCID:    Pubmed No.:28789357 Oncostatin M was associated with thrombosis in patients with atrial fibrillation PMCID:    Pubmed No.:28471981 Inhibitory effects of Shenkang injection and its main component emodin on the proliferation of high glucose‑induced renal mesangial cells through cell cycle regulation and induction of apoptosis PMCID:    Pubmed No.:27572472 Ibuprofen attenuates nephropathy in streptozotocin‑induced diabetic rats PMCID:    Pubmed No.:27109015 Effect of vascular endothelial growth factor siRNA and wild‑type p53 co‑expressing plasmid in MDA‑MB‑231 cells PMCID:    Pubmed No.:26573068 Nano-microcapsule basic fibroblast growth factor combined with hypoxia-inducible factor-1 improves random skin flap survival in rats PMCID:    Pubmed No.:26707180 Human trypsin inhibitor reduces the apoptosis of lipopolysaccharide‑induced human kidney‑2 cells by promoting mitochondrial fusion PMCID:    Pubmed No.:28713932 Recombinant lentivirus with enhanced expression of caudal‑related homeobox protein 2 inhibits human colorectal cancer cell proliferation in vitro PMCID:    Pubmed No.:25847407 Mda‑7/IL‑24 induces the differentiation of B cell lymphoma via activation of the P38 mitogen activated protein kinase signaling pathway PMCID:    Pubmed No.:28849038 Emodin promotes the arrest of human lymphoma Raji cell proliferation through the UHRF1‑DNMT3A‑∆Np73 pathways PMCID:    Pubmed No.:28901428 Tetrahydrocurcumin provides neuroprotection in rats after traumatic brain injury: autophagy and the PI3K/AKT pathways as a potential mechanism PMCID:    Pubmed No.:27916377 The effects of porcine pulmonary surfactant on smoke inhalation injury PMCID:    Pubmed No.:26073349 Silencing of HMGA2 promotes apoptosis and inhibits migration and invasion of prostate cancer cells PMCID:    Pubmed No.:27240983 The Effects of Aqueous Extract from Nardostachys chinensis Batalin on Blood Pressure and Cardiac Hypertrophy in Two-Kidney One-Clip Hypertensive Rats PMCID:    Pubmed No.:29234388 Ibuprofen Attenuates Cardiac Fibrosis in Streptozotocin-Induced Diabetic Rats PMCID:    Pubmed No.:25896805 Particularly interesting Cys‑His‑rich protein is highly expressed in human intracranial aneurysms and resists aneurysmal rupture PMCID:    Pubmed No.:28101173 Inhibition of the CyclinD1 promoter in response to sonic hedgehog signaling pathway transduction is mediated by Gli1 PMCID:    Pubmed No.:28123507 Effects of Angelica dahurica on obesity and fatty liver in mice PMCID:    Pubmed No.:27667509 Anti-proliferative potential of Glucosamine in renal cancer cells via inducing cell cycle arrest at G0/G1 phase PMCID:    Pubmed No.:28558682 LFG-500, a newly synthesized flavonoid, induces apoptosis in human ovarian carcinoma SKOV3 cells with involvement of the reactive oxygen species-mitochondria pathway PMCID:    Pubmed No.:28587346 Urocortin ameliorates diabetic cardiomyopathy in rats via the Akt/GSK-3β signaling pathway PMCID:    Pubmed No.:25667611 Anti‑inflammatory effects of Fagopyrum cymosum administered as a potential drug for ulcerative colitis PMCID:    Pubmed No.:29201175 The Inhibitory Effect of Rhein on Proliferation of High Glucose-induced Mesangial Cell Through Cell Cycle Regulation and Induction of Cell Apoptosis PMCID:    Pubmed No.:27279717 Epicatechin Plus Treadmill Exercise are Neuroprotective Against Moderate-stage Amyloid Precursor Protein/Presenilin 1 Mice PMCID:    Pubmed No.:27279698 Maternal betaine supplementation during gestation modifies hippocampal expression of GR and its regulatory miRNAs in neonatal piglets PMCID:    Pubmed No.:26875838 Effect of Qingxinkaiqiao compound on cortical mRNA expression of the apoptosis-related genes Bcl-2, BAX, caspase-3, and Aβ in an Alzheimer's disease rat model PMCID:    Pubmed No.:29933535 Augmented miR-10b expression associated with depressed expression of its target gene KLF4 involved in gastric carcinoma PMCID:    Pubmed No.:26191201 MicroRNA-221 promotes human non-small cell lung cancer cell H460 growth PMCID:    Pubmed No.:25932132 Honokiol induces cell cycle arrest and apoptosis in human gastric carcinoma MGC-803 cell line PMCID:    Pubmed No.:26131123 Long non-coding RNA UCA1 contributes to the progression of prostate cancer and regulates proliferation through KLF4-KRT6/13 signaling pathway PMCID:    Pubmed No.:26550172 Role of WNT1-inducible-signaling pathway protein 1 in etoposide resistance in lung adenocarcinoma A549 cells PMCID:    Pubmed No.:26628978 Dexmedetomidine alleviates the spinal cord ischemia-reperfusion injury through blocking mast cell degranulation PMCID:    Pubmed No.:26628956 Molecular regulation of apoptotic machinery and lipid metabolism by mTORC1/mTORC2 dual inhibitors in preclinical models of HER2+/PIK3CAmut breast cancer PMCID:    Pubmed No.:27563814 ST6Gal-I overexpression facilitates prostate cancer progression via the PI3K/Akt/GSK-3β/β-catenin signaling pathway PMCID:    Pubmed No.:27588482 Promoter methylation of PCDH10 by HOTAIR regulates the progression of gastrointestinal stromal tumors PMCID:    Pubmed No.:27659532 Differential effects of peptidoglycan on colorectal tumors and intestinal tissue post-pelvic radiotherapy PMCID:    Pubmed No.:27708223 Potential role of Wnt/β-catenin signaling in blastic transformation of chronic myeloid leukemia: cross talk between β-catenin and BCR-ABL PMCID:    Pubmed No.:27817074 High Uric Acid Activates the ROS-AMPK Pathway, Impairs CD68 Expression and Inhibits OxLDL-Induced Foam-Cell Formation in a Human Monocytic Cell Line, THP-1 PMCID:    Pubmed No.:27889764 Cytological study on the regulation of lymphocyte homing in the chicken spleen during LPS stimulation PMCID:    Pubmed No.:28061467 VEGF promotes cartilage angiogenesis by phospho-ERK1/2 activation of Dll4 signaling in temporomandibular joint osteoarthritis caused by chronic sleep disturbance in Wistar rats PMCID:    Pubmed No.:28147322 Melatonin protects against blood-brain barrier damage by inhibiting the TLR4/ NF-κB signaling pathway after LPS treatment in neonatal rats PMCID:    Pubmed No.:28404943 Interferon alpha antagonizes the anti-hepatoma activity of the oncolytic virus M1 by stimulating anti-viral immunity PMCID:    Pubmed No.:28445966 Effect of Y6, an epigallocatechin gallate derivative, on reversing doxorubicin drug resistance in human hepatocellular carcinoma cells PMCID:    Pubmed No.:28423656 EAAT3 promotes amino acid transport and proliferation of porcine intestinal epithelial cells PMCID:    Pubmed No.:27231847 Osterix acetylation at K307 and K312 enhances its transcriptional activity and is required for osteoblast differentiation PMCID:    Pubmed No.:27250035 A classical PKA inhibitor increases the oncolytic effect of M1 virus via activation of exchange protein directly activated by cAMP 1 PMCID:    Pubmed No.:27374176 Extracellular translationally controlled tumor protein promotes colorectal cancer invasion and metastasis through Cdc42/JNK/ MMP9 signaling PMCID:    Pubmed No.:27367023 AIM2 inhibits autophagy and IFN-β production during M. bovis infection PMCID:    Pubmed No.:27409673 TGF-β induces M2-like macrophage polarization via SNAIL-mediated suppression of a pro-inflammatory phenotype PMCID:    Pubmed No.:27418133 ColXV promotes adipocyte differentiation via inhibiting DNA methylation and cAMP/PKA pathway in mice PMCID:    Pubmed No.:28947959 Pathological expression of tissue factor confers promising antitumor response to a novel therapeutic antibody SC1 in triple negative breast cancer and pancreatic adenocarcinoma PMCID:    Pubmed No.:28938620 Silencing of HMGA2 suppresses cellular proliferation, migration, invasion, and epithelial–mesenchymal transition in bladder cancer PMCID:    Pubmed No.:26684800 Axon guidance molecule semaphorin3A is a novel tumor suppressor in head and neck squamous cell carcinoma PMCID:    Pubmed No.:26755661 UBE2T promotes nasopharyngeal carcinoma cell proliferation, invasion, and metastasis by activating the AKT/GSK3β/β-catenin pathway PMCID:    Pubmed No.:26943030 Inhibition of autophagy potentiates anticancer property of 20(S)-ginsenoside Rh2 by promoting mitochondria-dependent apoptosis in human acute lymphoblastic leukaemia cells PMCID:    Pubmed No.:27027340 Exosomes derived from gefitinib-treated EGFR-mutant lung cancer cells alter cisplatin sensitivity via up-regulating autophagy PMCID:    Pubmed No.:27029054 Activation of epithelial proliferation induced by Eimeria acervulina infection in the duodenum may be associated with cholesterol metabolism PMCID:    Pubmed No.:27050279 miR-675-5p enhances tumorigenesis and metastasis of esophageal squamous cell carcinoma by targeting REPS2 PMCID:    Pubmed No.:27120794 Focal adhesion kinase and paxillin promote migration and adhesion to fibronectin by swine skeletal muscle satellite cells PMCID:    Pubmed No.:27127174 Overexpression of HMGB3 protein promotes cell proliferation, migration and is associated with poor prognosis in urinary bladder cancer patients PMCID:    Pubmed No.:25647262 β-Elemene Reverses Chemoresistance of Breast Cancer via Regulating MDR-Related MicroRNA Expression PMCID:    Pubmed No.:25562151 Protective Effect of Spironolactone on Endothelial-to-Mesenchymal Transition in HUVECs via Notch Pathway PMCID:    Pubmed No.:25967959 Oroxylin A inhibits colitis by inactivating NLRP3 inflammasome PMCID:    Pubmed No.:28938606 Laminarin counteracts diet-induced obesity associated with glucagon-like peptide-1 secretion PMCID:    Pubmed No.:29245916 Reduced expression of BMP3 contributes to the development of pulmonary fibrosis and predicts the unfavorable prognosis in IIP patients PMCID:    Pubmed No.:29113323 Hoxa5 increases mitochondrial apoptosis by inhibiting Akt/mTORC1/S6K1 pathway in mice white adipocytes PMCID:    Pubmed No.:29221131 Metformin treatment after the hypoxia-ischemia attenuates brain injury in newborn rats PMCID:    Pubmed No.:29088867 Effect of alcohol on diethylnitrosamine-induced hepatic toxicity: Critical role of ROS, lipid accumulation, and mitochondrial dysfunction PMCID:    Pubmed No.:26198575 miR-382 targeting PTEN-Akt axis promotes liver regeneration PMCID:    Pubmed No.:26636539 Dihydroartemisinin and Curcumin Synergistically Induce Apoptosis in SKOV3 Cells Via Upregulation of MiR-124 Targeting Midkine PMCID:    Pubmed No.:28934730 Indirubin, a bisindole alkaloid from Isatis indigotica, reduces H1N1 susceptibility in stressed mice by regulating MAVS signaling PMCID:    Pubmed No.:29285277 Osterix Decreases the Chemosensitivity of Breast Cancer Cells by Upregulating GALNT14 PMCID:    Pubmed No.:29227978 Epigenetic silencing of NKD2, a major component of Wnt signaling, promotes breast cancer growth PMCID:    Pubmed No.:26124080 Alpha lipoic acid inhibits neural apoptosis via a mitochondrial pathway in rats following traumatic brain injury PMCID:    Pubmed No.:26055972 Salvianolic Acids for Injection (SAFI) promotes functional recovery and neurogenesis via sonic hedgehog pathway after stroke in mice PMCID:    Pubmed No.:28887094 NLRP12 collaborates with NLRP3 and NLRC4 to promote pyroptosis inducing ganglion cell death of acute glaucoma PMCID:    Pubmed No.:32295623 Inhibition of the mevalonate pathway enhances cancer cell oncolysis mediated by M1 virus PMCID:    Pubmed No.:29670091 Oxoeicosanoid receptor inhibition alleviates acute myocardial infarction through activation of BCAT1 PMCID:    Pubmed No.:33484341 Baicalin combats glutamate excitotoxicity via protecting glutamine synthetase from ROS-induced 20S proteasomal degradation PMCID:    Pubmed No.:32473460 Acidic pH transiently prevents the silencing of self-renewal and dampens microRNA function in embryonic stem cells PMCID:    Pubmed No.:36654154 The role of GLS1-mediated glutaminolysis/2-HG/H3K4me3 and GSH/ROS signals in Th17 responses counteracted by PPARγ agonists PMCID:    Pubmed No.:33754076 Lonicerin targets EZH2 to alleviate ulcerative colitis by autophagy-mediated NLRP3 inflammasome inactivation PMCID:    Pubmed No.:34589402 ATAD2 interacts with C/EBPβ to promote esophageal squamous cell carcinoma metastasis via TGF-β1/Smad3 signaling PMCID:    Pubmed No.:33757572 The inherited variations of a p53-responsive enhancer in 13q12.12 confer lung cancer risk by attenuating TNFRSF19 expression PMCID:    Pubmed No.:31126313 HEATR1 deficiency promotes pancreatic cancer proliferation and gemcitabine resistance by up-regulating Nrf2 signaling PMCID:    Pubmed No.:31785531 PER1 interaction with GPX1 regulates metabolic homeostasis under oxidative stress PMCID:    Pubmed No.:32896721 NGPF2 triggers synaptic scaling up through ALK-LIMK-cofilin-mediated mechanisms PMCID:    Pubmed No.:34407403 A Novel mTORC1/2 Inhibitor (MTI-31) Inhibits Tumor Growth, Epithelial–Mesenchymal Transition, Metastases, and Improves Antitumor Immunity in Preclinical Models of Lung Cancer PMCID:    Pubmed No.:30796032 A synonymous mutation in IGF-1 impacts the transcription and translation process of gene expression PMCID:    Pubmed No.:34938600 Oncostatin M promotes hepatic progenitor cell activation and hepatocarcinogenesis via macrophage-derived tumor necrosis factor-α PMCID:    Pubmed No.:34102284 The anti-microbial peptide LL-37/CRAMP levels are associated with acute heart failure and can attenuate cardiac dysfunction in multiple preclinical models of heart failure PMCID:    Pubmed No.:32483446 Resveratrol improves human umbilical cord-derived mesenchymal stem cells repair for cisplatin-induced acute kidney injury PMCID:    Pubmed No.:30237401 Arsenic trioxide ameliorates experimental autoimmune encephalomyelitis in C57BL/6 mice by inducing CD4+ T cell apoptosis PMCID:    Pubmed No.:32375831 Roxadustat prevents Ang II hypertension by targeting angiotensin receptors and eNOS PMCID:    Pubmed No.:34403364 Exercise downregulates HIPK2 and HIPK2 inhibition protects against myocardial infarction PMCID:    Pubmed No.:34837851 Sulforaphane Inhibits the Acquisition of Tobacco Smoke-Induced Lung Cancer Stem Cell-Like Properties via the IL-6/ΔNp63α/Notch Axis PMCID:    Pubmed No.:31367260 A selected small molecule prevents inflammatory osteolysis through restraining osteoclastogenesis by modulating PTEN activity PMCID:    Pubmed No.:33377656 Digoxin sensitizes gemcitabine-resistant pancreatic cancer cells to gemcitabine via inhibiting Nrf2 signaling pathway PMCID:    Pubmed No.:30735911 Astaxanthin ameliorates oxidative stress and neuronal apoptosis via SIRT1/Nrf2/Prx2/ASK1/P38 after traumatic brain injury in mice PMCID:    Pubmed No.:33326114 Systemic delivery of BACE1 siRNA through neuron-targeted nanocomplexes for treatment of Alzheimer's disease PMCID:    Pubmed No.:29679667 The Neuroprotective Effect of Short Chain Fatty Acids Against Sepsis-Associated Encephalopathy in Mice PMCID:    Pubmed No.:33584734 CBP Bromodomain Inhibition Rescues Mice From Lethal Sepsis Through Blocking HMGB1-Mediated Inflammatory Responses PMCID:    Pubmed No.:33603756 SIRT1 Promotes M2 Microglia Polarization via Reducing ROS-Mediated NLRP3 Inflammasome Signaling After Subarachnoid Hemorrhage. PMCID:    Pubmed No.:34899720 A20 Establishes Negative Feedback With TRAF6/NF-κB and Attenuates Early Brain Injury After Experimental Subarachnoid Hemorrhage PMCID:    Pubmed No.:34381441 Ceria Nanoparticles Fabricated with 6‐Aminohexanoic Acid that Overcome Systemic Inflammatory Response Syndrome PMCID:    Pubmed No.:30843374 Melatonin alleviates progression of uterine endometrial cancer by suppressing estrogen/ubiquitin C/SDHB-mediated succinate accumulation PMCID:    Pubmed No.:32061949 Dapagliflozin improves left ventricular remodeling and aorta sympathetic tone in a pig model of heart failure with preserved ejection fraction PMCID:    Pubmed No.:31429767 1,25‐Dihydroxyvitamin D exerts an antiaging role by activation of Nrf2‐antioxidant signaling and inactivation of p16/p53‐senescence signaling PMCID:    Pubmed No.:30907059 Bone marrow derived mesenchymal stem cells pretreated with erythropoietin accelerate the repair of acute kidney injury PMCID:    Pubmed No.:33292452 Design, synthesis and biological evaluation of chalcone analogues with novel dual antioxidant mechanisms as potential anti-ischemic stroke agents PMCID:    Pubmed No.:30972281 HDAC6/HNF4α loop mediated by miR-1 promotes bile acids-induced gastric intestinal metaplasia PMCID:    Pubmed No.:32705446 Proteasomal cysteine deubiquitinase inhibitor b-AP15 suppresses migration and induces apoptosis in diffuse large B cell lymphoma PMCID:    Pubmed No.:31694672 Porcine IGF-1R synonymous mutations in the intracellular domain affect cell proliferation and alter kinase activity PMCID:    Pubmed No.:32109480 The stemness of hepatocytes is maintained by high levels of lipopolysaccharide via YAP1 activation PMCID:    Pubmed No.:34112239 Bile acids increase intestinal marker expression via the FXR/SNAI2/miR-1 axis in the stomach PMCID:    Pubmed No.:34510400 Human Cancer Cells Sense Cytosolic Nucleic Acids Through the RIG-I–MAVS Pathway and cGAS–STING Pathway PMCID:    Pubmed No.:33490069 A Novel Function of Mitochondrial Phosphoenolpyruvate Carboxykinase as a Regulator of Inflammatory Response in Kupffer Cells. PMCID:    Pubmed No.:34970539 Enhanced responsiveness of platelets to vicagrel in IL‐10‐deficient mice through STAT3‐dependent up‐regulation of the hydrolase arylacetamide deacetylase in the intestine PMCID:    Pubmed No.:30825385 Luteolin ameliorates rat myocardial ischaemia–reperfusion injury through activation of peroxiredoxin II PMCID:    Pubmed No.:29782637 Pyrroloquinoline Quinone Prevents Estrogen Deficiency-Induced Osteoporosis by Inhibiting Oxidative Stress and Osteocyte Senescence PMCID:    Pubmed No.:30662347 Diastereoisomer-specific neurotoxicity of hexabromocyclododecane in human SH-SY5Y neuroblastoma cells PMCID:    Pubmed No.:31200309 PKCα mediated by the PI3K/Akt-FOXA1 cascade facilitates cypermethrin-induced hyperthyroidism PMCID:    Pubmed No.:33250241 Comparative Transcriptome Analysis Reveals the Protective Mechanism of Glycyrrhinic Acid for Deoxynivalenol-Induced Inflammation and Apoptosis in IPEC-J2 Cells PMCID:    Pubmed No.:33163144 Comparative Transcriptome Analysis Reveals the Protective Mechanism of Glycyrrhinic Acid for Deoxynivalenol-Induced Inflammation and Apoptosis in IPEC-J2 Cells PMCID:    Pubmed No.:33163144 MED1 Deficiency in Macrophages Accelerates Intimal Hyperplasia via ROS Generation and Inflammation PMCID:    Pubmed No.:34853629 Theaflavin 3, 3-Digallate Delays Ovarian Aging by Improving Oocyte Quality and Regulating Granulosa Cell Function PMCID:    Pubmed No.:34925699 Luteolin Confers Cerebroprotection after Subarachnoid Hemorrhage by Suppression of NLPR3 Inflammasome Activation through Nrf2-Dependent Pathway PMCID:    Pubmed No.:34777689 Impaired Autophagy Induced by oxLDL/β2GPI/anti-β2GPI Complex through PI3K/AKT/mTOR and eNOS Signaling Pathways Contributes to Endothelial Cell Dysfunction PMCID:    Pubmed No.:34221236 Protective effects of rutin on liver injury in type 2 diabetic db/db mice PMCID:    Pubmed No.:30138894 Discovery of novel 3-hydroxyandrosta-5,7-Diene-17-Carboxylic acid derivatives as anti-inflammatory bowel diseases (IBD) agents PMCID:    Pubmed No.:33933753 YY1: A novel therapeutic target for diabetic nephropathy orchestrated renal fibrosis PMCID:    Pubmed No.:31028762 PIM1 kinase promotes cell proliferation, metastasis and tumor growth of lung adenocarcinoma by potentiating the c-MET signaling pathway PMCID:    Pubmed No.:30583073 Association between ARID2 and RAS-MAPK pathway in intellectual disability and short stature PMCID:    Pubmed No.:33051312 Period1 mediates rhythmic metabolism of toxins by interacting with CYP2E1 PMCID:    Pubmed No.:33436540 Secreted KIAA1199 promotes the progression of rheumatoid arthritis by mediating hyaluronic acid degradation in an ANXA1-dependent manner PMCID:    Pubmed No.:33473125 Inhibition of AIM2 inflammasome activation alleviates GSDMD-induced pyroptosis in early brain injury after subarachnoid haemorrhage PMCID:    Pubmed No.:32001670 Dendritic cells-derived interferon-λ1 ameliorated inflammatory bone destruction through inhibiting osteoclastogenesis PMCID:    Pubmed No.:32488049 The circadian clock gene Bmal1 facilitates cisplatin-induced renal injury and hepatization PMCID:    Pubmed No.:32522976 Recombinant milk fat globule-EGF factor-8 reduces apoptosis via integrin β3/FAK/PI3K/AKT signaling pathway in rats after traumatic brain injury PMCID:    Pubmed No.:30154436 Isoform specific FBXW7 mediates NOTCH1 Abruptex mutation C1133Y deregulation in oral squamous cell carcinoma PMCID:    Pubmed No.:32792479 Melatonin alleviates hippocampal GR inhibition and depression-like behavior induced by constant light exposure in mice PMCID:    Pubmed No.:34794022 Heat stress affects fetal brain and intestinal function associated with the alterations of placental barrier in late pregnant mouse PMCID:    Pubmed No.:34695613 Effect of chlorogenic acid on alleviating inflammation and apoptosis of IPEC-J2 cells induced by deoxyniyalenol PMCID:    Pubmed No.:32961488 Novel biphenyl diester derivative AB-38b inhibits NLRP3 inflammasome through Nrf2 activation in diabetic nephropathy PMCID:    Pubmed No.:31768838 Nrf2 Down-Regulation by Camptothecin Favors Inhibiting Invasion, Metastasis and Angiogenesis in Hepatocellular Carcinoma PMCID:    Pubmed No.:34178646 Ursodeoxycholic acid protects against cisplatin-induced acute kidney injury and mitochondrial dysfunction through acting on ALDH1L2 PMCID:    Pubmed No.:32004633 Neuroprotective effects of INT-777 against Aβ1–42-induced cognitive impairment, neuroinflammation, apoptosis, and synaptic dysfunction in mice PMCID:    Pubmed No.:29935310 Neuroprotective effects of INT-777 against Aβ1–42-induced cognitive impairment, neuroinflammation, apoptosis, and synaptic dysfunction in mice PMCID:    Pubmed No.:29935310 Cerebroprotection by salvianolic acid B after experimental subarachnoid hemorrhage occurs via Nrf2- and SIRT1-dependent pathways PMCID:    Pubmed No.:29966698 Astragaloside IV reduces neuronal apoptosis and parthanatos in ischemic injury by preserving mitochondrial hexokinase-II PMCID:    Pubmed No.:30502455 Targeting the ILK/YAP axis by LFG-500 blocks epithelial–mesenchymal transition and metastasis PMCID:    Pubmed No.:33879841 Discovery of a Potent Kelch-Like ECH-Associated Protein 1-Nuclear Factor Erythroid 2-Related Factor 2 (Keap1–Nrf2) Protein–Protein Interaction Inhibitor with Natural Proline Structure as a Cytoprotective Agent against Acetaminophen-Induced Hepatotoxicity PMCID:    Pubmed No.:31283229 Sirtuin 1 alleviates diabetic neuropathic pain by regulating synaptic plasticity of spinal dorsal horn neurons PMCID:    Pubmed No.:30649099 Bmi1 Overexpression in Mesenchymal Stem Cells Exerts Antiaging and Antiosteoporosis Effects by Inactivating p16/p19 Signaling and Inhibiting Oxidative Stress PMCID:    Pubmed No.:30895687 Nrf2 antioxidant pathway suppresses Numb-mediated epithelial–mesenchymal transition during pulmonary fibrosis PMCID:    Pubmed No.:29362432 Upregulated osterix promotes invasion and bone metastasis and predicts for a poor prognosis in breast cancer PMCID:    Pubmed No.:30631043 Alpinetin exerts anti-colitis efficacy by activating AhR, regulating miR-302/DNMT-1/CREB signals, and therefore promoting Treg differentiation PMCID:    Pubmed No.:30166541 Suppression of SUN2 by DNA methylation is associated with HSCs activation and hepatic fibrosis PMCID:    Pubmed No.:30282980 LYW-6, a novel cryptotanshinone derived STAT3 targeting inhibitor, suppresses colorectal cancer growth and metastasis PMCID:    Pubmed No.:31982491 Food reward depends on TLR4 activation in dopaminergic neurons PMCID:    Pubmed No.:33971268 Enhancing PPARγ by HDAC inhibition reduces foam cell formation and atherosclerosis in ApoE deficient mice PMCID:    Pubmed No.:32621955 Sinusoidal Electromagnetic Fields Increase Peak Bone Mass in Rats by Activating Wnt10b/β‐Catenin in Primary Cilia of Osteoblasts PMCID:    Pubmed No.:30779853 Timosaponin AIII Induces G2/M Arrest and Apoptosis in Breast Cancer by Activating the ATM/Chk2 and p38 MAPK Signaling Pathways PMCID:    Pubmed No.:33628174 Piperazine-Derived α1D/1A Antagonist 1- Benzyl-N- (3-(4- (2-Methoxyphenyl) Piperazine-1-yl) Propyl) -1H- Indole-2- Carboxamide Induces Apoptosis in Benign Prostatic Hyperplasia Independently of α1-Adrenoceptor Blocking PMCID:    Pubmed No.:33584271 Neuroprotective Effects of Shenqi Fuzheng Injection in a Transgenic SOD1-G93A Mouse Model of Amyotrophic Lateral Sclerosis PMCID:    Pubmed No.:34737697 Angelicin Alleviates Post-Trauma Osteoarthritis Progression by Regulating Macrophage Polarization via STAT3 Signaling Pathway PMCID:    Pubmed No.:34177582 PTEN Methylation Promotes Inflammation and Activation of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis PMCID:    Pubmed No.:34305608 Berberine Ameliorates Subarachnoid Hemorrhage Injury via Induction of Sirtuin 1 and Inhibiting HMGB1/Nf-κB Pathway PMCID:    Pubmed No.:32754040 Actin polymerization state regulates osteogenic differentiation in human adipose-derived stem cells PMCID:    Pubmed No.:33858321 FasL-PDPK1 Pathway Promotes the Cytotoxicity of CD8 + T Cells During Ischemic Stroke PMCID:    Pubmed No.:32036560 Ambient PM2.5 caused cardiac dysfunction through FoxO1-targeted cardiac hypertrophy and macrophage-activated fibrosis in mice PMCID:    Pubmed No.:31978653 Oestrogen receptor α regulates the odonto/osteogenic differentiation of stem cells from apical papilla via ERK and JNK MAPK pathways PMCID:    Pubmed No.:30069950 Electroacupuncture Pretreatment Prevents Cognitive Impairment Induced by Cerebral Ischemia–Reperfusion via Adenosine A1 Receptors in Rats PMCID:    Pubmed No.:34413765 TBX15/miR-152/KIF2C pathway regulates breast cancer doxorubicin resistance via promoting PKM2 ubiquitination PMCID:    Pubmed No.:34663310 Novel Regulatory Roles of Wnt1 in Infection-Associated Colorectal Cancer PMCID:    Pubmed No.:29626750 Cytoplasmic eIF6 promotes OSCC malignant behavior through AKT pathway PMCID:    Pubmed No.:34922580 NOD2 promotes dopaminergic degeneration regulated by NADPH oxidase 2 in 6-hydroxydopamine model of Parkinson’s disease PMCID:    Pubmed No.:30157869 linc00968 inhibits the tumorigenesis and metastasis of lung adenocarcinoma via serving as a ceRNA against miR-9-5p and increasing CPEB3 PMCID:    Pubmed No.:33159015 linc00968 inhibits the tumorigenesis and metastasis of lung adenocarcinoma via serving as a ceRNA against miR-9-5p and increasing CPEB3 PMCID:    Pubmed No.:33159015 Long-term every-other-day administration of DMAMCL has little effect on aging and age-associated physiological decline in mice PMCID:    Pubmed No.:31048563 Improving radio-chemotherapy efficacy of prostate cancer by co-deliverying docetaxel and dbait with biodegradable nanoparticles PMCID:    Pubmed No.:31858836 SIRT1 Decreases Emotional Pain Vulnerability with Associated CaMKIIα Deacetylation in Central Amygdala PMCID:    Pubmed No.:32005763 PDK1 Regulates the Maintenance of Cell Body and the Development of Dendrites of Purkinje Cells by pS6 and PKCγ PMCID:    Pubmed No.:32487697 5-(3,4-Difluorophenyl)-3-(6-methylpyridin-3-yl)-1,2,4-oxadiazole (DDO-7263), a novel Nrf2 activator targeting brain tissue, protects against MPTP-induced subacute Parkinson's disease in mice by inhibiting the NLRP3 inflammasome and protects PC12 cells aga PMCID:    Pubmed No.:30615919 Tobacco smoke induced hepatic cancer stem cell-like properties through IL-33/p38 pathway PMCID:    Pubmed No.:30691509 Dual Mechanisms of Novel CD73-Targeted Antibody and Antibody–Drug Conjugate in Inhibiting Lung Tumor Growth and Promoting Antitumor Immune-Effector Function PMCID:    Pubmed No.:32943546 Maggot excretions/secretions promote diabetic wound angiogenesis via miR18a/19a – TSP-1 axis PMCID:    Pubmed No.:32277954 Curcumin Sensitizes Prolactinoma Cells to Bromocriptine by Activating the ERK/EGR1 and Inhibiting the AKT/GSK-3β Signaling Pathway In Vitro and In Vivo PMCID:    Pubmed No.:34463926 Curcumin Sensitizes Prolactinoma Cells to Bromocriptine by Activating the ERK/EGR1 and Inhibiting the AKT/GSK-3β Signaling Pathway In Vitro and In Vivo PMCID:    Pubmed No.:34463926 Discovery of 2-oxy-2-phenylacetic acid substituted naphthalene sulfonamide derivatives as potent KEAP1-NRF2 protein-protein interaction inhibitors for inflammatory conditions PMCID:    Pubmed No.:32866756 IL‐1β/IL‐1R1 signaling induced by intranasal lipopolysaccharide infusion regulates alpha‐synuclein pathology in the olfactory bulb, substantia nigra and striatum PMCID:    Pubmed No.:32678959 Membrane‐tethered Notch1 exhibits oncogenic property via activation of EGFR–PI3K–AKT pathway in oral squamous cell carcinoma PMCID:    Pubmed No.:30515785 White light emitting diode induces autophagy in hippocampal neuron cells through GSK-3-mediated GR and RORα pathways PMCID:    Pubmed No.:30923260 Islet-cell autoantigen 69 mediates the antihyperalgesic effects of electroacupuncture on inflammatory pain by regulating spinal glutamate receptor subunit 2 phosphorylation through protein interacting with C-kinase 1 in mice PMCID:    Pubmed No.:30699097 Expression of a short antibody heavy chain peptide effectively antagonizes adenosine 2A receptor in vitro and in vivo PMCID:    Pubmed No.:32308059 Corydalis saxicola Bunting total alkaloids attenuate paclitaxel-induced peripheral neuropathy through PKCε/p38 MAPK/TRPV1 signaling pathway PMCID:    Pubmed No.:34281577 Piperine, as a TAS2R14 agonist, stimulates secretion of glucagon-like peptide-1 in human enteroendocrine cell line Caco-2 PMCID:    Pubmed No.:34881772 Alhagi honey polysaccharides attenuate intestinal injury and immune suppression in cyclophosphamide-induced mice PMCID:    Pubmed No.:34128029 Crosstalk between soluble PDGF-BB and PDGFRβ promotes astrocytic activation and synaptic recovery in the hippocampus after subarachnoid hemorrhage PMCID:    Pubmed No.:31162947 JNK1 regulates RANKL-induced osteoclastogenesis via activation of a novel Bcl-2-Beclin1-autophagy pathway PMCID:    Pubmed No.:31295022 Diallyl disulfide alleviates inflammatory osteolysis by suppressing osteoclastogenesis via NF-κB–NFATc1 signal pathway PMCID:    Pubmed No.:30857415 Silica-induced initiation of circular ZC3H4 RNA/ZC3H4 pathway promotes the pulmonary macrophage activation PMCID:    Pubmed No.:29401612 Activation of silent information regulator 1 exerts a neuroprotective effect after intracerebral hemorrhage by deacetylating NF-κB/p65 PMCID:    Pubmed No.:33289070 Effect of gomisin A on osteoblast differentiation in high glucose-mediated oxidative stress PMCID:    Pubmed No.:31790903 Rare ginsenosides ameliorate lipid overload-induced myocardial insulin resistance via modulating metabolic flexibility PMCID:    Pubmed No.:31005715 The protective effect of WKYMVm peptide on inflammatory osteolysis through regulating NF-κB and CD9/gp130/STAT3 signalling pathway PMCID:    Pubmed No.:31837208 Novel Sesquiterpene Glycoside from Loquat Leaf Alleviates Type 2 Diabetes Mellitus Combined with Nonalcoholic Fatty Liver Disease by Improving Insulin Resistance, Oxidative Stress, Inflammation, and Gut Microbiota Composition PMCID:    Pubmed No.:34783554 trans 10, cis 12, but Not cis 9, trans 11 Conjugated Linoleic Acid Isomer Enhances Exercise Endurance by Increasing Oxidative Skeletal Muscle Fiber Type via Toll-like Receptor 4 Signaling in Mice PMCID:    Pubmed No.:34928153 trans 10, cis 12, but Not cis 9, trans 11 Conjugated Linoleic Acid Isomer Enhances Exercise Endurance by Increasing Oxidative Skeletal Muscle Fiber Type via Toll-like Receptor 4 Signaling in Mice PMCID:    Pubmed No.:34928153 Dietary Addition of Sodium Butyrate Contributes to Attenuated Feeding-Induced Hepatocyte Apoptosis in Dairy Goats PMCID:    Pubmed No.:30173520 Benzannulated 5,5-spiroketal sesquiterpenes from the roots of Angelica Pubescens PMCID:    Pubmed No.:33422712 Pulsed Electromagnetic Fields Ameliorate Skeletal Deterioration in Bone Mass, Microarchitecture, and Strength by Enhancing Canonical Wnt Signaling-Mediated Bone Formation in Rats with Spinal Cord Injury PMCID:    Pubmed No.:33108939 Butyrate Suppresses Glucose Metabolism of Colorectal Cancer Cells via GPR109a-AKT Signaling Pathway and Enhances Chemotherapy PMCID:    Pubmed No.:33855046 Resveratrol Improves Mitochondrial Biogenesis Function and Activates PGC-1α Pathway in a Preclinical Model of Early Brain Injury Following Subarachnoid Hemorrhage PMCID:    Pubmed No.:33968980 Imperatorin inhibits mitogen-activated protein kinase and nuclear factor kappa-B signaling pathways and alleviates neuroinflammation in ischemic stroke PMCID:    Pubmed No.:34674376 Hypoxia-inducible factor prolyl hydroxylase inhibitor roxadustat (FG-4592) protects against cisplatin-induced acute kidney injury PMCID:    Pubmed No.:29581249 Effects of ALA-PDT on the Healing of Mouse Skin Wounds Infected With Pseudomonas aeruginosa and Its Related Mechanisms. PMCID:    Pubmed No.:33344449 USP18 deubiquitinates and stabilizes Twist1 to promote epithelial-mesenchymal transition in glioblastoma cells PMCID:    Pubmed No.:32368392 Targeting PI3K/Akt/Nrf2 pathway by glabridin alleviates acetaminophen-induced hepatic injury in rats PMCID:    Pubmed No.:33932887 Selenium nanoparticles fabricated in laminarin polysaccharides solutions exert their cytotoxicities in HepG2 cells by inhibiting autophagy and promoting apoptosis PMCID:    Pubmed No.:31284007 N16 suppresses RANKL-mediated osteoclatogenesis by down-regulating RANK expression PMCID:    Pubmed No.:31751723 Paired associative stimulation improves synaptic plasticity and functional outcomes after cerebral ischemia PMCID:    Pubmed No.:31290455 Transplantation of human endometrial perivascular cells with elevated CYR61 expression induces angiogenesis and promotes repair of a full-thickness uterine injury in rat PMCID:    Pubmed No.:31215503 Circular RNA SIPA1L1 regulates osteoblastic differentiation of stem cells from apical papilla via miR-204-5p/ALPL pathway PMCID:    Pubmed No.:33138854 Inhibition of Uncoupling Protein 2 Enhances the Radiosensitivity of Cervical Cancer Cells by Promoting the Production of Reactive Oxygen Species PMCID:    Pubmed No.:32190174 Astragalus membranaceus Injection Suppresses Production of Interleukin-6 by Activating Autophagy through the AMPK-mTOR Pathway in Lipopolysaccharide-Stimulated Macrophages PMCID:    Pubmed No.:32724488 SOCS2 Inhibits Mitochondrial Fatty Acid Oxidation via Suppressing LepR/JAK2/AMPK Signaling Pathway in Mouse Adipocytes PMCID:    Pubmed No.:32733634 Activation of GPR55 attenuates cognitive impairment and neurotoxicity in a mouse model of Alzheimer's disease induced by Aβ1–42 through inhibiting RhoA/ROCK2 pathway PMCID:    Pubmed No.:34363866 A novel compound AB38b attenuates oxidative stress and ECM protein accumulation in kidneys of diabetic mice through modulation of Keap1/Nrf2 signaling PMCID:    Pubmed No.:31645661 Exploring the protective effects of schizandrol A in acute myocardial ischemia mice by comprehensive metabolomics profiling integrated with molecular mechanism studies PMCID:    Pubmed No.:32123298 Diabetes downregulates peptide transporter 1 in the rat jejunum: possible involvement of cholate-induced FXR activation PMCID:    Pubmed No.:32341465 Sirt1 inhibits renal tubular cell epithelial–mesenchymal transition through YY1 deacetylation in diabetic nephropathy PMCID:    Pubmed No.:32555442 Short-chain fatty acids exert opposite effects on the expression and function of p-glycoprotein and breast cancer resistance protein in rat intestine PMCID:    Pubmed No.:32555444 Fluoxetine induces lipid metabolism abnormalities by acting on the liver in patients and mice with depression PMCID:    Pubmed No.:30150788 Suppression of MIF-induced neuronal apoptosis may underlie the therapeutic effects of effective components of Fufang Danshen in the treatment of Alzheimer's disease PMCID:    Pubmed No.:29770796 Ruscogenin attenuates particulate matter-induced acute lung injury in mice via protecting pulmonary endothelial barrier and inhibiting TLR4 signaling pathway PMCID:    Pubmed No.:32855531 Effect of hyperglycemia on microglial polarization after cerebral ischemia-reperfusion injury in rats PMCID:    Pubmed No.:34052292 Oxymatrine alleviated hepatic lipid metabolism via regulating miR-182 in non-alcoholic fatty liver disease PMCID:    Pubmed No.:32679144 1‐L‐MT, an IDO inhibitor, prevented colitis‐associated cancer by inducing CDC20 inhibition‐mediated mitotic death of colon cancer cells PMCID:    Pubmed No.:29607498 mTORC1 promotes mineralization via p53 pathway PMCID:    Pubmed No.:33508145 Differential skeletal response in adult and aged rats to independent and combinatorial stimulation with pulsed electromagnetic fields and mechanical vibration PMCID:    Pubmed No.:31908035 Astaxanthin mitigates subarachnoid hemorrhage injury primarily by increasing sirtuin 1 and inhibiting the Toll‐like receptor 4 signaling pathway PMCID:    Pubmed No.:30048156 Thrombin/PAR-1 activation induces endothelial damages via NLRP1 inflammasome in gestational diabetes PMCID:    Pubmed No.:32059841 Porcine milk exosome miRNAs protect intestinal epithelial cells against deoxynivalenol-induced damage PMCID:    Pubmed No.:32145262 Thiomyristoyl ameliorates colitis by blocking the differentiation of Th17 cells and inhibiting SIRT2-induced metabolic reprogramming PMCID:    Pubmed No.:33310666 Ferulic acid attenuates oxidative DNA damage and inflammatory responses in microglia induced by benzo(a)pyrene PMCID:    Pubmed No.:31699670 Inhibition of GPR17 with cangrelor improves cognitive impairment and synaptic deficits induced by Aβ1–42 through Nrf2/HO-1 and NF-κB signaling pathway in mice PMCID:    Pubmed No.:34781121 JLX001 ameliorates cerebral ischemia injury by modulating microglial polarization and compromising NLRP3 inflammasome activation via the NF-κB signaling pathway PMCID:    Pubmed No.:34740080 5-HT2A Receptor and 5-HT Degradation Play a Crucial Role in Atherosclerosis by Modulating Macrophage Foam Cell Formation, Vascular Endothelial Cell Inflammation, and Hepatic Steatosis PMCID:    Pubmed No.:33536397 The RhoA/ROCK pathway mediates high glucose-induced cardiomyocyte apoptosis via oxidative stress, JNK, and p38MAPK pathways PMCID:    Pubmed No.:29745021 Serum- and glucocorticoid-inducible kinase 1 promotes insulin resistance in adipocytes via degradation of insulin receptor substrate 1 PMCID:    Pubmed No.:33724645 3-(1H-Benzo[d]imidazol-6-yl)-5-(4-fluorophenyl)-1,2,4-oxadiazole (DDO7232), a Novel Potent Nrf2/ARE Inducer, Ameliorates DSS-Induced Murine Colitis and Protects NCM460 Cells against Oxidative Stress via ERK1/2 Phosphorylation PMCID:    Pubmed No.:29887940 DNA damage checkpoint pathway modulates the regulation of skeletal growth and osteoblastic bone formation by parathyroid hormone-related peptide PMCID:    Pubmed No.:29805302 TIPRL, a Novel Tumor Suppressor, Suppresses Cell Migration, and Invasion Through Regulating AMPK/mTOR Signaling Pathway in Gastric Cancer PMCID:    Pubmed No.:32719745 Discovery of a Keap1-dependent peptide PROTAC to knockdown Tau by ubiquitination-proteasome degradation pathway PMCID:    Pubmed No.:29407955 The loss of dopaminergic neurons in DEC1 deficient mice potentially involves the decrease of PI3K/Akt/GSK3β signaling PMCID:    Pubmed No.:31884423 Epothilone B prevents lipopolysaccharide-induced inflammatory osteolysis through suppressing osteoclastogenesis via STAT3 signaling pathway PMCID:    Pubmed No.:32527985 Neuromedin B modulates phosphate-induced vascular calcification PMCID:    Pubmed No.:34674793 miR-103/107 promote ER stress-mediated apoptosis via targeting the Wnt3a/β-catenin/ATF6 pathway in preadipocytes PMCID:    Pubmed No.:29483204 Hsa-let-7c controls the committed differentiation of IGF-1-treated mesenchymal stem cells derived from dental pulps by targeting IGF-1R via the MAPK pathways PMCID:    Pubmed No.:29650947 A Novel Phytochemical, DIM, Inhibits Proliferation, Migration, Invasion and TNF-α Induced Inflammatory Cytokine Production of Synovial Fibroblasts From Rheumatoid Arthritis Patients by Targeting MAPK and AKT/mTOR Signal Pathway PMCID:    Pubmed No.:31396207 A Novel Derivative of the Natural Product Danshensu Suppresses Inflammatory Responses to Alleviate Caerulein-Induced Acute Pancreatitis PMCID:    Pubmed No.:30425719 Dietary Supplementation of L-Arginine and N-Carbamylglutamate Attenuated the Hepatic Inflammatory Response and Apoptosis in Suckling Lambs with Intrauterine Growth Retardation PMCID:    Pubmed No.:32322162 MFG-E8 attenuates inflammation in subarachnoid hemorrhage by driving microglial M2 polarization PMCID:    Pubmed No.:33245889 FGF21 promotes functional recovery after hypoxic-ischemic brain injury in neonatal rats by activating the PI3K/Akt signaling pathway via FGFR1/β-klotho PMCID:    Pubmed No.:30802446 Jmjd3 is involved in the susceptibility to depression induced by maternal separation via enhancing the neuroinflammation in the prefrontal cortex and hippocampus of male rats PMCID:    Pubmed No.:32084453 Protective effects of FGF10 on neurovascular unit in a rat model of neonatal hypoxic-ischemic brain injury PMCID:    Pubmed No.:32610105 Pretreatment with low-dose fimasartan ameliorates NLRP3 inflammasome-mediated neuroinflammation and brain injury after intracerebral hemorrhage PMCID:    Pubmed No.:30171865 Role of TREM-1 in the development of early brain injury after subarachnoid hemorrhage PMCID:    Pubmed No.:33727099 Decursinol angelate ameliorates 12-O-tetradecanoyl phorbol-13-acetate (TPA) -induced NF-κB activation on mice ears by inhibiting exaggerated inflammatory cell infiltration, oxidative stress and pro-inflammatory cytokine production PMCID:    Pubmed No.:31351099 Anthraquinone-type inhibitor of α-glucosidase enhances glucose uptake by activating an insulin-like signaling pathway in C2C12 myotubes PMCID:    Pubmed No.:31071387 Toosendanin Shows Potent Efficacy Against Human Ovarian Cancer through Caspase-Dependent Mitochondrial Apoptotic Pathway PMCID:    Pubmed No.:34521317 Chicoric Acid Improves Heart and Blood Responses to Hypobaric Hypoxia in Tibetan Yaks PMCID:    Pubmed No.:29433395 β‐arrestin 2 negatively regulates NOD2 signalling pathway through association with TRAF6 in microglia after cerebral ischaemia/reperfusion injury PMCID:    Pubmed No.:30793522 DNA Hypomethylation of GR Promoters is Associated with GR Activation and BDNF/AKT/ERK1/2‐Induced Hippocampal Neurogenesis in Mice Derived From Folic‐Acid‐Supplemented Dams PMCID:    Pubmed No.:30920123 Dysregulation of Krüppel-like factor 12 in the development of endometrial cancer PMCID:    Pubmed No.:30482501 Hypoxanthine Induces Muscular ATP Depletion and Fatigue via UCP2 PMCID:    Pubmed No.:33746782 ERα and/or ERβ activation ameliorates cognitive impairment, neurogenesis and apoptosis in type 2 diabetes mellitus mice PMCID:    Pubmed No.:30201537 Protective effects of melatonin on sepsis-induced liver injury and dysregulation of gluconeogenesis in rats through activating SIRT1/STAT3 pathway PMCID:    Pubmed No.:31234024 Metabolomic profiling of metoprolol-induced cardioprotection in a murine model of acute myocardial ischemia PMCID:    Pubmed No.:31972362 Curcumin regulates endogenous and exogenous metabolism via Nrf2-FXR-LXR pathway in NAFLD mice PMCID:    Pubmed No.:29860219 FTO inhibits UPRmt-induced apoptosis by activating JAK2/STAT3 pathway and reducing m6A level in adipocytes PMCID:    Pubmed No.:34212271 Exosomes derived from autologous dermal fibroblasts promote diabetic cutaneous wound healing through the Akt/β-catenin pathway PMCID:    Pubmed No.:33685347 Parathyroid hormone enhances the osteo/odontogenic differentiation of dental pulp stem cells via ERK and P38 MAPK pathways PMCID:    Pubmed No.:31276209 Sodium fluoride regulates the osteo/odontogenic differentiation of stem cells from apical papilla by modulating autophagy PMCID:    Pubmed No.:30767218 AIM2 promotes non‐small‐cell lung cancer cell growth through inflammasome‐dependent pathway PMCID:    Pubmed No.:30953357 LncRNA AK077216 promotes RANKL‐induced osteoclastogenesis and bone resorption via NFATc1 by inhibition of NIP45 PMCID:    Pubmed No.:30132869 Long Noncoding RNA ANRIL Supports Proliferation of Adult T-Cell Leukemia Cells through Cooperation with EZH2 PMCID:    Pubmed No.:30258009 Deficiency of the IRE1α-Autophagy Axis Enhances the Antitumor Effects of the Oncolytic Virus M1 PMCID:    Pubmed No.:29263275 Maternal Separation-Induced Histone Acetylation Correlates with BDNF-Programmed Synaptic Changes in an Animal Model of PTSD with Sex Differences PMCID:    Pubmed No.:33245480 Fucoxanthin Mitigates Subarachnoid Hemorrhage-Induced Oxidative Damage via Sirtuin 1-Dependent Pathway PMCID:    Pubmed No.:32876840 Inhibition of IRE1/JNK pathway in HK‐2 cells subjected to hypoxia‐reoxygenation attenuates mesangial cells‐derived extracellular matrix production PMCID:    Pubmed No.:33043579 NR4A1 counteracts JNK activation incurred by ER stress or ROS in pancreatic β‐cells for protection PMCID:    Pubmed No.:33124187 Design and Green Synthesis of Piperlongumine Analogs and Their Antioxidant Activity against Cerebral Ischemia-Reperfusion Injury PMCID:    Pubmed No.:31491086 Role of mitochondrial calcium uniporter‐mediated Ca2+ and iron accumulation in traumatic brain injury PMCID:    Pubmed No.:30756474 Low levels of AMPK promote epithelial‐mesenchymal transition in lung cancer primarily through HDAC4‐ and HDAC5‐mediated metabolic reprogramming PMCID:    Pubmed No.:32519437 Role of CSE-Produced H2S on Cerebrovascular Relaxation via RhoA-ROCK Inhibition and Cerebral Ischemia-Reperfusion Injury in Mice PMCID:    Pubmed No.:30406996 Emodin prevents renal ischemia-reperfusion injury via suppression of CAMKII/DRP1-mediated mitochondrial fission PMCID:    Pubmed No.:34793771 Hippocampal SIRT1 improves cognitive impairment by deacetylating tau protein in diabetic models PMCID:    Pubmed No.:34861210 A pentacyclic triterpene derivative possessing polyhydroxyl ring A suppresses growth of HeLa cells by reactive oxygen species-dependent NF-κB pathway PMCID:    Pubmed No.:30153443 Iso-suillin-induced DNA damage leading to cell cycle arrest and apoptosis arised from p53 phosphorylation in A549 cells PMCID:    Pubmed No.:34217708 Erythropoietin alleviates hepatic steatosis by activating SIRT1-mediated autophagy PMCID:    Pubmed No.:29522896 Integrating bioinformatics with pharmacological evaluation for illustrating the action mechanism of herbal formula Jiao'e mixture in suppressing lung carcinoma PMCID:    Pubmed No.:34400263 Ginseng root extract attenuates inflammation by inhibiting the MAPK/NF-κB signaling pathway and activating autophagy and p62-Nrf2-Keap1 signaling in vitro and in vivo PMCID:    Pubmed No.:34648903 Inhibitory effect of INT-777 on lipopolysaccharide-induced cognitive impairment, neuroinflammation, apoptosis, and synaptic dysfunction in mice PMCID:    Pubmed No.:30144494 Silymarin ameliorates the disordered glucose metabolism of mice with diet-induced obesity by activating the hepatic SIRT1 pathway PMCID:    Pubmed No.:33901577 Melatonin ameliorates excessive PINK1/Parkin-mediated mitophagy by enhancing SIRT1 expression in granulosa cells of PCOS PMCID:    Pubmed No.:32343612 The expression of diacylglycerol kinase isoforms α and ζ correlates with the progression of experimental autoimmune encephalomyelitis in rats PMCID:    Pubmed No.:34312706 Selective Antagonism of Bcl-xL Potentiates M1 Oncolysis by Enhancing Mitochondrial Apoptosis PMCID:    Pubmed No.:28750564 Atractylenolide III ameliorates cerebral ischemic injury and neuroinflammation associated with inhibiting JAK2/STAT3/Drp1-dependent mitochondrial fission in microglia PMCID:    Pubmed No.:30981186 Decreased immunoglobulin G in brain regions of elder female APOE4-TR mice accompany with Aβ accumulation PMCID:    Pubmed No.:30700991 LonP1 regulates mitochondrial network remodeling through the PINK1/Parkin pathway during myoblast differentiation PMCID:    Pubmed No.:32936696 Resveratrol chemosensitizes adriamycin‐resistant breast cancer cells by modulating miR‐122‐5p PMCID:    Pubmed No.:31155753 The influence of the Chuyou Yuyang granule on the Toll‐like receptor/nuclear factor‐κB signal pathway in Helicobacter pylori‐positive peptic ulcer patients PMCID:    Pubmed No.:31034651 Melatonin enhances SIRT1 to ameliorate mitochondrial membrane damage by activating PDK1/Akt in granulosa cells of PCOS PMCID:    Pubmed No.:34758863 The role of apatinib combined with paclitaxel (aluminum binding type) in platinum-resistant ovarian cancer PMCID:    Pubmed No.:32958014 Alpha-Mangostin Ameliorates Bleomycin-Induced Pulmonary Fibrosis in Mice Partly Through Activating Adenosine 5′-Monophosphate-Activated Protein Kinase PMCID:    Pubmed No.:31798444 MicroRNA-141-5p Acts as a Tumor Suppressor via Targeting RAB32 in Chronic Myeloid Leukemia PMCID:    Pubmed No.:32038235 YiQiFuMai Powder Injection Attenuates Coronary Artery Ligation-Induced Heart Failure Through Improving Mitochondrial Function via Regulating ROS Generation and CaMKII Signaling Pathways PMCID:    Pubmed No.:31031629 Effects of D-Chiro-Inositol on Glucose Metabolism in db/db Mice and the Associated Underlying Mechanisms PMCID:    Pubmed No.:32273844 Hederagenin Attenuates Cerebral Ischaemia/Reperfusion Injury by Regulating MLK3 Signalling PMCID:    Pubmed No.:32848779 Indoprofen exerts a potent therapeutic effect against sepsis by alleviating high mobility group box 1-mediated inflammatory responses PMCID:    Pubmed No.:34755645 Albumin fusion improves the pharmacokinetics and in vivo antitumor efficacy of canine interferon gamma PMCID:    Pubmed No.:30639219 Artemisinin Derivatives Inhibit Non-small Cell Lung Cancer Cells Through Induction of ROS-dependent Apoptosis/Ferroptosis PMCID:    Pubmed No.:34093811 Extracellular Glutamate-Induced mTORC1 Activation via the IR/IRS/PI3K/Akt Pathway Enhances the Expansion of Porcine Intestinal Stem Cells PMCID:    Pubmed No.:31382738 Probiotics Exert Protective Effect against Sepsis-Induced Cognitive Impairment by Reversing Gut Microbiota Abnormalities PMCID:    Pubmed No.:33284020 Clostridium butyricum Attenuates Chronic Unpredictable Mild Stress-Induced Depressive-Like Behavior in Mice via the Gut-Brain Axis PMCID:    Pubmed No.:30040410 Long-Term High-Fat Diet Decreases Hepatic Iron Storage Associated with Suppressing TFR2 and ZIP14 Expression in Rats PMCID:    Pubmed No.:30350980 A novel Notch1 missense mutation (C1133Y) in the Abruptex domain exhibits enhanced proliferation and invasion in oral squamous cell carcinoma PMCID:    Pubmed No.:29321718 Amelioration of non-alcoholic fatty liver disease by sodium butyrate is linked to the modulation of intestinal tight junctions in db/db mice PMCID:    Pubmed No.:33216087 The Neuropeptide Spexin Promotes the Osteoblast Differentiation of MC3T3-E1 Cells via the MEK/ERK Pathway and Bone Regeneration in a Mouse Calvarial Defect Model PMCID:    Pubmed No.:34951679 Heat exposure impairs porcine oocyte quality with suppressed actin expression in cumulus cells and disrupted F-actin formation in transzonal projections PMCID:    Pubmed No.:32647569 Protection of the enhanced Nrf2 deacetylation and its downstream transcriptional activity by SIRT1 in myocardial ischemia/reperfusion injury PMCID:    Pubmed No.:34403762 Lidocaine Inhibits Myoblast Cell Migration and Myogenic Differentiation Through Activation of the Notch Pathway PMCID:    Pubmed No.:33688167 Caveolin-1 knockout mice have altered serum N-glycan profile and sialyltransferase tissue expression PMCID:    Pubmed No.:34462883 NEDD4 Negatively Regulates GITR via Ubiquitination in Immune Microenvironment of Melanoma PMCID:    Pubmed No.:31824170 miR-141-3p regulates saturated fatty acid-induced cardiomyocyte apoptosis through Notch1/PTEN/AKT pathway via targeting PSEN1 PMCID:    Pubmed No.:34897970 Pro‑atherogenic activation of A7r5 cells induced by the oxLDL/β2GPI/anti‑β2GPI complex PMCID:    Pubmed No.:30085340 The positive role of vitronectin in radiation induced lung toxicity: the in vitro and in vivo mechanism study PMCID:    Pubmed No.:29661186 Hepatoprotective Effect of Apigenin Against Liver Injury via the Non-canonical NF-κB Pathway In Vivo and In Vitro PMCID:    Pubmed No.:32458347 Protective effects of Genistein on the cognitive deficits induced by chronic sleep deprivation PMCID:    Pubmed No.:32115816 Sarsasapogenin ameliorates diabetes‐associated memory impairment and neuroinflammation through down‐regulation of PAR‐1 receptor PMCID:    Pubmed No.:33885189 Protective effects of sarsasapogenin against early stage of diabetic nephropathy in rats PMCID:    Pubmed No.:29682805 Simvastatin prevents and ameliorates depressive behaviors via neuroinflammatory regulation in mice PMCID:    Pubmed No.:30699879 WD Repeat Domain 1 Deficiency Inhibits Neointima Formation in Mice Carotid Artery by Modulation of Smooth Muscle Cell Migration and Proliferation PMCID:    Pubmed No.:32868491 A novel compound AB-38b improves diabetes-associated cognitive decline in mice via activation of Nrf2/ARE pathway PMCID:    Pubmed No.:31132419 Isoflurane anesthesia in aged mice and effects of A1 adenosine receptors on cognitive impairment PMCID:    Pubmed No.:29345054 Inhibition of Autophagy with Chloroquine Enhanced Sinoporphyrin Sodium Mediated Photodynamic Therapy-induced Apoptosis in Human Colorectal Cancer Cells PMCID:    Pubmed No.:30662343 Interleukin-27 prevents LPS-induced inflammatory osteolysis by inhibiting osteoclast formation and function PMCID:    Pubmed No.:30972153 P27 deletion enhances hematopoiesis by paracrine action of IL22 secreted from bone marrow mesenchymal stem cells PMCID:    Pubmed No.:32269712 Chemokine receptor 7 overexpression promotes mesenchymal stem cell migration and proliferation via secreting Chemokine ligand 12 PMCID:    Pubmed No.:29317710 Inactivation of TSC1 promotes epithelial-mesenchymal transition of renal tubular epithelial cells in mouse diabetic nephropathy PMCID:    Pubmed No.:31235817 Inhibitory effects of isocryptotanshinone on gastric cancer PMCID:    Pubmed No.:29915371 A multifunctional DNA nano-scorpion for highly efficient targeted delivery of mRNA therapeutics PMCID:    Pubmed No.:29976947 Attenuation of melanogenesis by Nymphaea nouchali (Burm. f) flower extract through the regulation of cAMP/CREB/MAPKs/MITF and proteasomal degradation of tyrosinase PMCID:    Pubmed No.:30224716 Neuroprotective Effects of Rhynchophylline Against Aβ1–42-Induced Oxidative Stress, Neurodegeneration, and Memory Impairment Via Nrf2–ARE Activation PMCID:    Pubmed No.:34170454 DR7 encoded by human herpesvirus 6 promotes glioma development and progression PMCID:    Pubmed No.:30881135 Mas-related G protein-coupled receptor D participates in inflammatory pain by promoting NF-κB activation through interaction with TAK1 and IKK complex PMCID:    Pubmed No.:33080316 The biphasic effects of the oxLDL/β2GPI/anti-β2GPI complex on VSMC proliferation and apoptosis PMCID:    Pubmed No.:30738928 BMP9 inhibits the proliferation and migration of fibroblast-like synoviocytes in rheumatoid arthritis via the PI3K/AKT signaling pathway PMCID:    Pubmed No.:31203157 MCTR3 reduces LPS-induced acute lung injury in mice via the ALX/PINK1 signaling pathway PMCID:    Pubmed No.:33268042 Saikosaponin-d attenuated lipopolysaccharide-induced depressive-like behaviors via inhibiting microglia activation and neuroinflammation PMCID:    Pubmed No.:31926446 Inhibiting NLRP3 inflammasome with MCC950 ameliorates perioperative neurocognitive disorders, suppressing neuroinflammation in the hippocampus in aged mice PMCID:    Pubmed No.:32087497 Effects of interleukin-6 and IL-6/AMPK signaling pathway on mitochondrial biogenesis and astrocytes viability under experimental septic condition PMCID:    Pubmed No.:29674256 Neuroprotective effects of novel compound Tozan on cognition, neurogenesis and apoptosis in diabetes PMCID:    Pubmed No.:34734023 Syngeneic bone marrow transplantation in combination with PI3K inhibitor reversed hyperglycemia in later-stage streptozotocin-induced diabetes PMCID:    Pubmed No.:34988151 Impairment of Intestinal Monocarboxylate Transporter 6 Function and Expression in Diabetic Rats Induced by Combination of High-Fat Diet and Low Dose of Streptozocin: Involvement of Butyrate–Peroxisome Proliferator-Activated Receptor-γ Activation PMCID:    Pubmed No.:30923035 Prediction of Atorvastatin Pharmacokinetics in High-Fat Diet and Low-Dose Streptozotocin-Induced Diabetic Rats Using a Semiphysiologically Based Pharmacokinetic Model Involving Both Enzymes and Transporters PMCID:    Pubmed No.:31399507 ClC-3 chloride channel protein induces G1 arrest in hepatocellular carcinoma Hep3B cells PMCID:    Pubmed No.:29749557 The Role of CDR1as in Proliferation and Differentiation of Human Umbilical Cord-Derived Mesenchymal Stem Cells PMCID:    Pubmed No.:31281369 Polydatin protects SH-SY5Y in models of Parkinson's disease by promoting Atg5-mediated but parkin-independent autophagy PMCID:    Pubmed No.:31926197 Curcumin-activated autophagy plays a negative role in its anti-osteoclastogenic effect PMCID:    Pubmed No.:31678610 Paternal systemic inflammation induces offspring programming of growth and liver regeneration in association with Igf2 upregulation PMCID:    Pubmed No.:32882328 PSTPIP2 Inhibits the Inflammatory Response and Proliferation of Fibroblast-Like Synoviocytes in vitro PMCID:    Pubmed No.:30564127 MiR-27a-3p enhances the cisplatin sensitivity in hepatocellular carcinoma cells through inhibiting PI3K/Akt pathway PMCID:    Pubmed No.:34096570 Identification of extracellular vesicles-transported miRNAs in Erlotinib-resistant head and neck squamous cell carcinoma PMCID:    Pubmed No.:32157550 Quercetin improves nonalcoholic fatty liver by ameliorating inflammation, oxidative stress, and lipid metabolism in db/db mice PMCID:    Pubmed No.:31452288 hucMSCs Attenuate IBD through Releasing miR148b-5p to Inhibit the Expression of 15-lox-1 in Macrophages PMCID:    Pubmed No.:31275059 A Novel Putative Role of TNK1 in Atherosclerotic Inflammation Implicating the Tyk2/STAT1 Pathway PMCID:    Pubmed No.:32694928 Both LmCYP4G genes function in decreasing cuticular penetration of insecticides in Locusta migratoria PMCID:    Pubmed No.:32419293 C-peptide ameliorates high glucose-induced podocyte dysfunction through the regulation of the Notch and TGF-β signaling pathways PMCID:    Pubmed No.:33901627 Effect of simvastatin and microRNA-21 inhibitor on metastasis and progression of human salivary adenoid cystic carcinoma PMCID:    Pubmed No.:30021341 CXCR1/CXCR2 antagonist G31P inhibits nephritis in a mouse model of uric acid nephropathy PMCID:    Pubmed No.:30257327 Norfloxacin suppresses Leptospira-induced inflammation through inhibiting p65 and ERK phosphorylation and NLRP3 inflammasome activation PMCID:    Pubmed No.:34826552 The novel GLP-1/GIP dual agonist DA3-CH is more effective than liraglutide in reducing endoplasmic reticulum stress in diabetic rats with cerebral ischemia-reperfusion injury PMCID:    Pubmed No.:33500109 Essential oil from Fructus Alpinia zerumbet (fruit of Alpinia zerumbet (Pers.) Burtt.et Smith) protected against aortic endothelial cell injury and inflammation in vitro and in vivo PMCID:    Pubmed No.:30880260 Effects of Agriophyllum squarrosum extracts on glucose metabolism in KKAy mice and the associated underlying mechanisms PMCID:    Pubmed No.:31158442 Phenylethanoid glycosides of Callicarpa kwangtungensis Chun exert cardioprotective effect by weakening Na+-K+-ATPase/Src/ERK1/2 pathway and inhibiting apoptosis mediated by oxidative stress and inflammation PMCID:    Pubmed No.:32311484 Mechanisms dissection of the combination GRS derived from ShengMai preparations for the treatment of myocardial ischemia/reperfusion injury PMCID:    Pubmed No.:32946961 Activation of ERα and/or ERβ ameliorates cognitive impairment and apoptosis in streptozotocin-induced diabetic mice PMCID:    Pubmed No.:30096284 A balanced game: chicken macrophage response to ALV-J infection PMCID:    Pubmed No.:30841905 Dexmedetomidine Attenuates Neuroinflammatory–Induced Apoptosis after Traumatic Brain Injury via Nrf2 signaling pathway PMCID:    Pubmed No.:31478596 Baicalin Protects Mice Brain From Apoptosis in Traumatic Brain Injury Model Through Activation of Autophagy PMCID:    Pubmed No.:30686973 Carbon ion combined with tigecycline inhibits lung cancer cell proliferation by inducing mitochondrial dysfunction PMCID:    Pubmed No.:33065148 PGRN−/− TAMs-derived exosomes inhibit breast cancer cell invasion and migration and its mechanism exploration PMCID:    Pubmed No.:33181174 Effects of low-dose ALA-PDT on fibroblast photoaging induced by UVA irradiation and the underlying mechanisms PMCID:    Pubmed No.:31075320 HHQ-4, a quinoline derivate, preferentially inhibits proliferation of glucose-deprived breast cancer cells as a GRP78 down-regulator PMCID:    Pubmed No.:31022492 Fluoride induces apoptosis via inhibiting SIRT1 activity to activate mitochondrial p53 pathway in human neuroblastoma SH-SY5Y cells PMCID:    Pubmed No.:29609003 Upregulation of α enolase (ENO1) crotonylation in colorectal cancer and its promoting effect on cancer cell metastasis PMCID:    Pubmed No.:34547627 CTRP9 induces iNOS expression through JAK2/STAT3 pathway in Raw 264.7 and peritoneal macrophages PMCID:    Pubmed No.:31837806 METTL3 regulates skeletal muscle specific miRNAs at both transcriptional and post-transcriptional levels PMCID:    Pubmed No.:33740664 Role and mechanism of miR-4778-3p and its targets NR2C2 and Med19 in cervical cancer radioresistance PMCID:    Pubmed No.:30473219 Bmi-1 determines the stemness of renal stem or progenitor cells PMCID:    Pubmed No.:32819581 Porcine Milk Exosome MiRNAs Attenuate LPS-Induced Apoptosis through Inhibiting TLR4/NF-κB and p53 Pathways in Intestinal Epithelial Cells PMCID:    Pubmed No.:31429552 Paclitaxel‑resistant gastric cancer MGC‑803 cells promote epithelial‑to‑mesenchymal transition and chemoresistance in paclitaxel‑sensitive cells via exosomal delivery of miR‑155‑5p PMCID:    Pubmed No.:30365045 Shp2 regulates PM2.5-induced airway epithelial barrier dysfunction by modulating ERK1/2 signaling pathway PMCID:    Pubmed No.:34252507 MicroRNA-29b-3p enhances radiosensitivity through modulating WISP1-mediated mitochondrial apoptosis in prostate cancer cells PMCID:    Pubmed No.:33033519 Secreted Wnt6 mediates diabetes-associated centrosome amplification via its receptor FZD4 PMCID:    Pubmed No.:31618077 Yap regulates mitochondrial structural remodeling during myoblast differentiation PMCID:    Pubmed No.:29898377 Effects of ionizing radiation and HLY78 on the zebrafish embryonic developmental toxicity PMCID:    Pubmed No.:30321647 Tert-butylhydroquinone enhanced angiogenesis and astrocyte activation by activating nuclear factor-E2-related factor 2/heme oxygenase-1 after focal cerebral ischemia in mice PMCID:    Pubmed No.:31283926 Small intestine proteomics coupled with serum metabolomics reveal disruption of amino acid metabolism in Chinese hamsters with type 2 diabetes mellitus PMCID:    Pubmed No.:32428569 Acute exposure to deoxynivalenol inhibits porcine enteroid activity via suppression of the Wnt/β-catenin pathway PMCID:    Pubmed No.:30690062 Absent in melanoma 2 suppresses epithelial‐mesenchymal transition via Akt and inflammasome pathways in human colorectal cancer cells PMCID:    Pubmed No.:31210372 miR‐125a‐3p suppresses the growth and progression of papillary thyroid carcinoma cell by targeting MMP11 PMCID:    Pubmed No.:31489990 Luteolin attenuates high glucose-induced podocyte injury via suppressing NLRP3 inflammasome pathway PMCID:    Pubmed No.:30935950 Breviscapine provides a neuroprotective effect after traumatic brain injury by modulating the Nrf2 signaling pathway PMCID:    Pubmed No.:31042302 Astrocyte elevated gene‐1 induces autophagy in diabetic cardiomyopathy through upregulation of KLF4 PMCID:    Pubmed No.:30520133 Dietary betaine activates hepatic VTGII expression in laying hens associated with hypomethylation of GR gene promoter and enhanced GR expression PMCID:    Pubmed No.:29375826 Morphological and molecular response of small intestine to lactulose and hydrogen-rich water in female piglets fed Fusarium mycotoxins contaminated diet PMCID:    Pubmed No.:30805184 MiR-876-5p modulates head and neck squamous cell carcinoma metastasis and invasion by targeting vimentin PMCID:    Pubmed No.:30181714 Ezrin interacts with L-periaxin by the “head to head and tail to tail” mode and influences the location of L-periaxin in Schwann cell RSC96 PMCID:    Pubmed No.:31931020 Tprn is essential for the integrity of stereociliary rootlet in cochlear hair cells in mice PMCID:    Pubmed No.:30159668 YAP mediates the interaction between the Hippo and PI3K/Akt pathways in mesangial cell proliferation in diabetic nephropathy PMCID:    Pubmed No.:32816106 miRNA-320a inhibits glioma cell invasion and migration by directly targeting aquaporin 4 PMCID:    Pubmed No.:29484417 Androgen receptor induces EPHA3 expression by interacting with transcription factor SP1 PMCID:    Pubmed No.:29917167 Flavonoids extracted from mulberry (Morus alba L.) leaf improve skeletal muscle mitochondrial function by activating AMPK in type 2 diabetes PMCID:    Pubmed No.:31639486 Autophagy mediated by JNK1 resists apoptosis through TRAF3 degradation in osteoclastogenesis PMCID:    Pubmed No.:31654668 Insulin exacerbated high glucose-induced epithelial-mesenchymal transition in prostatic epithelial cells BPH-1 and prostate cancer cells PC-3 via MEK/ERK signaling pathway PMCID:    Pubmed No.:32561286 Luteolin alleviates NLRP3 inflammasome activation and directs macrophage polarization in lipopolysaccharide-stimulated RAW264.7 cells PMCID:    Pubmed No.:29423011 N-acetylcysteine prevents orchiectomy-induced osteoporosis by inhibiting oxidative stress and osteocyte senescence PMCID:    Pubmed No.:31396339 Inhibition of mitochondrial complex I by rotenone protects against acetaminophen-induced liver injury PMCID:    Pubmed No.:30787978 Pyrroloquinoline quinone prevents knee osteoarthritis by inhibiting oxidative stress and chondrocyte senescence PMCID:    Pubmed No.:30972174 Deletion of p16 prevents estrogen deficiency-induced osteoporosis by inhibiting oxidative stress and osteocyte senescence PMCID:    Pubmed No.:32194914 Mitochondrial-targeted antioxidant MitoQ provides neuroprotection and reduces neuronal apoptosis in experimental traumatic brain injury possibly via the Nrf2-ARE pathway PMCID:    Pubmed No.:30018728 Sodium aescinate provides neuroprotection in experimental traumatic brain injury via the Nrf2-ARE pathway PMCID:    Pubmed No.:32014567 Deletion of aquaporin-4 aggravates brain pathology after blocking of the meningeal lymphatic drainage PMCID:    Pubmed No.:30347264 Diet containing stearic acid increases food reward-related behaviors in mice compared with oleic acid PMCID:    Pubmed No.:32822805 Delayed metformin treatment improves functional recovery following traumatic brain injury via central AMPK-dependent brain tissue repair PMCID:    Pubmed No.:32858129 Curcumin provides neuroprotection in model of traumatic brain injury via the Nrf2-ARE signaling pathway PMCID:    Pubmed No.:29626606 Post-exercise Effects and Long-Term Training Adaptations of Hormone Sensitive Lipase Lipolysis Induced by High-Intensity Interval Training in Adipose Tissue of Mice. PMCID:    Pubmed No.:33324231 Docosahexaenoic acid inhibits hepatic stellate cell activation to attenuate liver fibrosis in a PPARγ-dependent manner PMCID:    Pubmed No.:31437794 Hesperetin derivative attenuates CCl4-induced hepatic fibrosis and inflammation by Gli-1-dependent mechanisms PMCID:    Pubmed No.:31473406 Protective effects of tauroursodeoxycholic acid on lipopolysaccharide-induced cognitive impairment and neurotoxicity in mice PMCID:    Pubmed No.:30986644 Geniposide, a sonic hedgehog signaling inhibitor, inhibits the activation of hepatic stellate cell PMCID:    Pubmed No.:31005778 Effect of silencing HIF-1α gene on testicle spermatogenesis function in varicocele rats PMCID:    Pubmed No.:31377879 Combination therapy with F5/35 fiber chimeric conditionally replicative adenoviruses expressing IL‐24 enhances the antitumor effect of temozolomide against melanoma PMCID:    Pubmed No.:30406970 The tail domain of PRRSV NSP2 plays a key role in aggrephagy by interacting with 14-3-3ε PMCID:    Pubmed No.:32811532 Chitosan-gold nanoparticles mediated gene delivery of c-myb facilitates osseointegration of dental implants in ovariectomized rat PMCID:    Pubmed No.:30307328
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.

Price/Size :

USD 368/1mg/vial



Tips: 

For phospho antibody, we provide phospho peptide(0.5mg) and non-phospho peptide(0.5mg).

Describe :

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.

Formula:

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.

Storage:

The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C. 


Note :

This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.
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