RRM2 polyclonal antibody 
Datasheet
COA
MSDS
SHIP
Product Name :
RRM2 polyclonal antibody Background :
Ribonucleotide reductase M2 subunit is one of two subunits that constitute ribonucleotide reductase, the enzyme that catalyzes the conversion of ribonucleotide 5'-diphosphates into 2'-deoxyribonucleotides, a rate-limiting step in the production of 2'-deoxyribonucleoside 5'-diphosphates (dNTP) required for DNA synthesis and repair that is required for DNA synthesis and repair. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
RRM2 polyclonal antibody detects endogenous levels of RRM2 protein. Immunogen :
Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human RRM2 (NP_001025.1). Conjugate :
Unconjugated Modification :
Unmodified
RRM2 polyclonal antibody Background :
Ribonucleotide reductase M2 subunit is one of two subunits that constitute ribonucleotide reductase, the enzyme that catalyzes the conversion of ribonucleotide 5'-diphosphates into 2'-deoxyribonucleotides, a rate-limiting step in the production of 2'-deoxyribonucleoside 5'-diphosphates (dNTP) required for DNA synthesis and repair that is required for DNA synthesis and repair. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
RRM2 polyclonal antibody detects endogenous levels of RRM2 protein. Immunogen :
Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human RRM2 (NP_001025.1). Conjugate :
Unconjugated Modification :
Unmodified
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Western blot analysis of extracts of HeLa cells, using RRM2 antibody at 1:1000 dilution. -
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma using RRM2 pAb at dilution of 1:100 (40x lens). -
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma using RRM2 pAb at dilution of 1:100 (40x lens). -
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma using RRM2 pAb at dilution of 1:100 (40x lens).
Downregulation of the long non‑coding RNA FOXD2‑AS1 inhibits cell proliferation, migration and invasion in osteosarcoma
PMCID: Pubmed No.:31115575
RRM2 Mediates the Anti-Tumor Effect of the Natural Product Pectolinarigenin on Glioblastoma Through Promoting CDK1 Protein Degradation by Increasing Autophagic Flux
PMCID: Pubmed No.:35651787
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.
Price/Size :
USD 368/1mg/vial
Tips:
For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).Describe :
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.Formula:
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.
Storage:
The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C.
Note :
This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.