Product Name :
p-ERβ (S105) Peptide Applications :
Blocking Background :
Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including ERa and ERb, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. They are located in the nucleus, though some estrogen receptors associate with the cell surface membrane and can be rapidly activated by exposure of cells to estrogen. ERa and ERb have been shown to be differentially activated by various ligands. Receptor-ligand interactions trigger a cascade of events, including dissociation from heat shock proteins, receptor dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. Alternative Name :
ER BETA; ER BETA; ER-beta; Erb; ESR 2; ESR 2; ESR B; ESR B; ESR BETA; ESR BETA; ESR2; ESR2; ESR2; ESRB; ESRB; ESTRB; Estrogen Receptor 2; Estrogen Receptor 2; Estrogen receptor beta; NR3A2; Nuclear receptor subfamily 3 group A member 2; Swiss-Prot :
Q92731 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide p-ERβ (S105). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using AP0318 p-ERβ (S105) pAb.
p-ERβ (S105) Peptide Applications :
Blocking Background :
Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including ERa and ERb, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. They are located in the nucleus, though some estrogen receptors associate with the cell surface membrane and can be rapidly activated by exposure of cells to estrogen. ERa and ERb have been shown to be differentially activated by various ligands. Receptor-ligand interactions trigger a cascade of events, including dissociation from heat shock proteins, receptor dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. Alternative Name :
ER BETA; ER BETA; ER-beta; Erb; ESR 2; ESR 2; ESR B; ESR B; ESR BETA; ESR BETA; ESR2; ESR2; ESR2; ESRB; ESRB; ESTRB; Estrogen Receptor 2; Estrogen Receptor 2; Estrogen receptor beta; NR3A2; Nuclear receptor subfamily 3 group A member 2; Swiss-Prot :
Q92731 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide p-ERβ (S105). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using AP0318 p-ERβ (S105) pAb.
Blocking peptide available as AP0318PP