Product Name :
p-DNAM 1(S329) Peptide Applications :
Blocking Background :
DNAM 1 is a receptor expressed by peripheral blood T lymphocytes that is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T lymphocytes. DNAM 1 is broadly expressed on T cells, NK cells, platelets, monocytes and a subset of B cells. DNAM-1 is also expressed by a subset of CD3 positive thymocytes. This antibody is reported to inhibit T- and NK cell mediated cytotoxicity against tumour cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells. Alternative Name :
adhesion glycoprotein; CD226 antigen; CD226 molecule; DNAM 1; DNAM1; DNAX accessory molecule 1; platelet and T cell activation antigen 1; PTA1; T lineage specific activation antigen 1 antigen; TLiSA1; Swiss-Prot :
Q15762 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide p-DNAM 1(S329). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using AP0313 p-DNAM 1(S329) pAb.
p-DNAM 1(S329) Peptide Applications :
Blocking Background :
DNAM 1 is a receptor expressed by peripheral blood T lymphocytes that is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T lymphocytes. DNAM 1 is broadly expressed on T cells, NK cells, platelets, monocytes and a subset of B cells. DNAM-1 is also expressed by a subset of CD3 positive thymocytes. This antibody is reported to inhibit T- and NK cell mediated cytotoxicity against tumour cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells. Alternative Name :
adhesion glycoprotein; CD226 antigen; CD226 molecule; DNAM 1; DNAM1; DNAX accessory molecule 1; platelet and T cell activation antigen 1; PTA1; T lineage specific activation antigen 1 antigen; TLiSA1; Swiss-Prot :
Q15762 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide p-DNAM 1(S329). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using AP0313 p-DNAM 1(S329) pAb.
Blocking peptide available as AP0313PP