p-PKC θ (T538) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
p-PKC θ (T538) Peptide Applications :
Blocking Background :
Members of the protein kinase C (PKC) family of serine/threonine kinases play a key role in regulating the differentiation and growth of diverse cell types. PKC theta is a member of the PKC family, and its predominant expression in hematopoietic cells suggests that it may play a role in signal transduction and growth regulatory pathways unique to these cells. PKC theta is a Ca(2+)-independent PKC isoform that is selectively expressed in T lymphocytes (and muscle), and it is thought to play an important role in T cell receptor-induced activation. Among several PKC isoenzymes expressed in T cells, PKC theta is unique in being rapidly recruited to the site of TCR clustering. It has been shown that PKC theta is essential for TCR-mediated T-cell activation, but it is dispensable during TCR-dependent thymocyte development. Alternative Name :
Protein kinase C theta type; nPKC-theta; PRKCQ; PRKCT Swiss-Prot :
Q04759 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide p-PKC θ (T538). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using AP0292 p-PKC θ (T538) pAb.
p-PKC θ (T538) Peptide Applications :
Blocking Background :
Members of the protein kinase C (PKC) family of serine/threonine kinases play a key role in regulating the differentiation and growth of diverse cell types. PKC theta is a member of the PKC family, and its predominant expression in hematopoietic cells suggests that it may play a role in signal transduction and growth regulatory pathways unique to these cells. PKC theta is a Ca(2+)-independent PKC isoform that is selectively expressed in T lymphocytes (and muscle), and it is thought to play an important role in T cell receptor-induced activation. Among several PKC isoenzymes expressed in T cells, PKC theta is unique in being rapidly recruited to the site of TCR clustering. It has been shown that PKC theta is essential for TCR-mediated T-cell activation, but it is dispensable during TCR-dependent thymocyte development. Alternative Name :
Protein kinase C theta type; nPKC-theta; PRKCQ; PRKCT Swiss-Prot :
Q04759 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide p-PKC θ (T538). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using AP0292 p-PKC θ (T538) pAb.
Blocking peptide available as AP0292PP