p-eIF4B(Ser422) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
p-eIF4B(Ser422) Peptide Applications :
Blocking Background :
Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.It is phosphorylated at Ser-422 by RPS6KA1 and RPS6KB1.phosphorylation enhances the affinity of EIF4B for the EIF3 complex Alternative Name :
EIF 4B; EIF-4B; Eukaryotic initiation factor 4B; Eukaryotic translation initiation factor 4B; PRO1843; Swiss-Prot :
P23588 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide p-eIF4B(Ser422). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using AP0084 p-eIF4B(Ser422) pAb.
p-eIF4B(Ser422) Peptide Applications :
Blocking Background :
Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.It is phosphorylated at Ser-422 by RPS6KA1 and RPS6KB1.phosphorylation enhances the affinity of EIF4B for the EIF3 complex Alternative Name :
EIF 4B; EIF-4B; Eukaryotic initiation factor 4B; Eukaryotic translation initiation factor 4B; PRO1843; Swiss-Prot :
P23588 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide p-eIF4B(Ser422). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using AP0084 p-eIF4B(Ser422) pAb.
Blocking peptide available as AP0084PP