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Product Catalog
CB1 (F189) Antibody
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Catalogue No : BS2712
| Host | Reactivity | Size | Application | stock | price | cart |
| BS2712 | H,M,R | 100μg | WB IHC |  |
258.00 |  |
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Contact information
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Product
1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Purification & Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Specificity
CB1 (F189) antibody detects endogenous levels of CB1 protein
Applications (Recommended Dilutions)
WB: 1:500~1:1000 IHC: 1:50~1:200
Western Blot(WB)
Western blot (WB) analysis of CB1 (F189) antibody in extracts from HT-29 cells.
Immunohistochemistry (IHC)
Immunohistochemistry (IHC) analyzes of CB1 (F189) antibody in paraffin-embedded mouse brain tissue.
Storage&Stability
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Background
The cannabinoid receptors (CB1 and CB2) are G protein-coupled receptors that inhibit adenylate cyclase activity in response to psychoactive cannabinoids. CB1 is expressed in brain tissue and, in low levels, in testis. CB2 is expressed only by cells of the immune system. The cannabinoid receptors mediate most of the cannabinoid-induced responses in a dose-dependent, stereoselective manner. This response system is thought to be involved in specific brain functions, such as nociception, control of movement, memory and neuroendocrine regulation, as well as having a possible role in brain development. In addition, CB1 may mediate the addictive behavior involved with the use of psychoactive cannabinoids, such as THC in marijuana.