β–Amyloid 1-42 (N-Terminal) Antibody

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Catalogue No : BS6005

Alternative Name for β–Amyloid 1-42 (N-Terminal) Antibody
Host   Reactivity Size Application stock price cart
BS6005 H,M,R 100ug WB IHC 258.00
Contact information

Email:shdiahds@163.com
Phone:+1-909-839-7620
Fax:+1-909-839-7620

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Product

1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.

Purification & Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity

β–Amyloid 1-42 antibody detects endogenous levels of β–Amyloid 1-42 protein.

Applications (Recommended Dilutions)

WB: 1:500~1:1000 IHC: 1:50~1:200

Western Blot(WB)

Western blot (WB) analysis of β–Amyloid 1-42 antibody in extracts from mouse AD brain tissue .

Immunohistochemistry (IHC)

Immunohistochemistry (IHC) analyzes of β–Amyloid 1-42 antibody in paraffin-embedded mouse AD brain tissue .

Storage&Stability

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Background

Proteolytic cleavage of the amyloid protein precursor (APP, also designated A4) leads to the formation of a 4 kDa Amyloidβ/A4 protein (also designatedβ–Amyloid).This protein is involved in the formation of neurofibrillary tanges and plaques that characterize the senile plaques of Alzheimer patients. Amyloid deposition is associated with a variety of neurological disorders in addition to Alzheimer’s disease, including type II diabetes and Down’s syndrome.